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Full-Text Articles in Biomedical Engineering and Bioengineering

Biosensing Enhancement Of Dengue Virus Using Microballoon Mixers On Centrifugal Microfluidic Platforms May 2015

Biosensing Enhancement Of Dengue Virus Using Microballoon Mixers On Centrifugal Microfluidic Platforms

Faculty of Engineering University of Malaya

Dengue is the current leading cause of death among children in several Latin American and Asian countries. Due to poverty in areas where the disease is prevalent and the high cost of conventional diagnostic systems, low cost devices are needed to reduce the burden caused by dengue infection. Centrifugal microfluidic platforms are an alternative solution to reduce costs and increase the availability of a rapid diagnostic system. The rate of chemical reactions in such devices often depends on the efficiency of the mixing techniques employed in their microfluidic networks. This paper introduces a micromixer that operates by the expansion and …


Development Of Novel Passive Check Valves For The Microfluidic Cd Platform Feb 2015

Development Of Novel Passive Check Valves For The Microfluidic Cd Platform

Faculty of Engineering University of Malaya

Microfluidic CD platforms are utilized to perform different biological processes and chemical analyses. In general, a microfluidic CD implements the centrifugal force that is created by the spinning of the platform to pump liquid through the microfluidic network of chambers and channels. Over the last few decades, a wide range of active and passive valving methods were proposed and tested on various microfluidic platforms. Most of the presented valves are too complex to design and involve lengthy fabrication processes. In this paper, easy to fabricate air and liquid check valves for centrifugal microfluidic platforms are presented: a Terminal Check Valve …


Ultrasound-Based Tissue Characterization And Classification Of Fatty Liver Disease: A Screening And Diagnostic Paradigm Feb 2015

Ultrasound-Based Tissue Characterization And Classification Of Fatty Liver Disease: A Screening And Diagnostic Paradigm

Faculty of Engineering University of Malaya

Fatty Liver Disease (FLD) is a progressively prevalent disease that is present in about 15% of the world population. Normally benign and reversible if detected at an early stage, FLD, if left undetected and untreated, can progress to an irreversible advanced liver disease, such as fibrosis, cirrhosis, liver cancer and liver failure, which can cause death. Ultrasound (US) is the most widely used modality to detect FLD. However, the accuracy of US-based diagnosis depends on both the training and expertise of the radiologist. US-based Computer Aided Diagnosis (CAD) techniques for FLD detection can improve accuracy, speed and objectiveness of the …