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Biomedical Engineering and Bioengineering Commons

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Biomedical Devices and Instrumentation

Electronic Theses and Dissertations

Theses/Dissertations

2021

Diagnostics

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Full-Text Articles in Biomedical Engineering and Bioengineering

Detecting Viral Particles In Vitro Using Photoacoustic Flow Cytometry, Anie-Pier Samson Dec 2021

Detecting Viral Particles In Vitro Using Photoacoustic Flow Cytometry, Anie-Pier Samson

Electronic Theses and Dissertations

The Covid-19 pandemic is a powerful example of just how damaging the rapid spread of an unknown virus can be. Viruses have the ability to spread rapidly amongst individuals if not treated and controlled. The first key step towards treatment is the timely and specific diagnosis of the virus causing the infection. An innovative method for the rapid detection of viral particles in solution consists of tagging the viral particles paired with using photoacoustic flow cytometry to irradiate the particles and get a signal. The high affinity of Streptavidin for Biotin can be used to bind Streptavidin-coated microspheres to biotinylated …