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Full-Text Articles in Biomedical Engineering and Bioengineering
Localized Intra-Arterial Drug Delivery Device For Stroke Treatment, Benjamin Yip
Localized Intra-Arterial Drug Delivery Device For Stroke Treatment, Benjamin Yip
Biomedical Engineering Undergraduate Honors Theses
Strokes are one of the leading causes of death and long-term disability in the United States, and according to the Centers for Disease Control and Prevention more than 795,000 people experience a stroke every year. Around 87% of all strokes are ischemic strokes making it the most common form of stroke. While ischemic strokes are treatable, current devices and methods still result in high mortality rates and high risks of hemorrhaging after treatment. The aim of this study is to design and test a prototype of a novel device for the localized delivery of thrombolytics to treat ischemic strokes. The …
Clot Analogs For The Development Of Improved Treatment Methods In Ischemic Stroke, Charles A. Rieth
Clot Analogs For The Development Of Improved Treatment Methods In Ischemic Stroke, Charles A. Rieth
Biomedical Engineering Undergraduate Honors Theses
According to the CDC, nearly 800,000 individuals experience stroke each year in the United States [1]. Greater than 70% of strokes are of ischemic etiology and involve the occlusion of key arteries in the cardiovascular system [2]. Tissue plasminogen activator (IV-tPA) is the current gold standard for thrombolytic approaches [3]; however, this therapeutic is only effective between 3 and 4.5 hours from the patient’s last know well [4]. As a result, less than 5% of acute ischemic stroke patients receive IV-tPA. In order to increase the viability of AIS treatment as a whole, it is essential that thrombolytic techniques are …