Open Access. Powered by Scholars. Published by Universities.®

Biomedical Engineering and Bioengineering Commons

Open Access. Powered by Scholars. Published by Universities.®

Biomedical Devices and Instrumentation

Biomedical Engineering Undergraduate Honors Theses

Theses/Dissertations

2020

Articles 1 - 3 of 3

Full-Text Articles in Biomedical Engineering and Bioengineering

Characterization Of Oxone Mediated Tempo-Oxidized Nano Cellulose Mixed-Matrix Membranes During Ultrafiltration And Hemodialysis, Kristyn Robling May 2020

Characterization Of Oxone Mediated Tempo-Oxidized Nano Cellulose Mixed-Matrix Membranes During Ultrafiltration And Hemodialysis, Kristyn Robling

Biomedical Engineering Undergraduate Honors Theses

The ninth leading cause of death in the United States is kidney disease, and hemodialysis is the process most commonly prescribed for treatment. It utilizes a selectively permeable membrane filter to remove toxins such as urea from the blood and retain necessary protein levels. However, traditional filters, such as cellulose triacetate, used during dialysis can be inefficient in terms of separation performance and reduction of fouling. Recent exploration of nanoparticles has resulted in the creation of Oxone Mediated TEMPO-Oxidized Nano Cellulose which has properties that are believed to increase hydrophilicity, increase tensile capacity, decrease membrane resistance and lower fouling, making …


Redesign And Quantitative Assessment Of An Accelerated Venous Valve Fatigue Apparatus, Megan Kueh May 2020

Redesign And Quantitative Assessment Of An Accelerated Venous Valve Fatigue Apparatus, Megan Kueh

Biomedical Engineering Undergraduate Honors Theses

Chronic venous insufficiency (CVI) is a form of cardiovascular disease that is caused when valves in the leg become incompetent. Current treatment methods serve to manage symptoms, but there are currently no ways to treat the underlying cause of CVI. A venous valve prosthetic made from a xenograft of a bovine jugular vein is one possible treatment method currently in the research phase. Prosthetic valves must be tested with an accelerated wear tester prior to approval for clinical testing. Although such testers exist for heart valves, physiological differences between heart and venous valves restrict the use those testers on venous …


Analysis Of Blood Purification Studies On Oxone Mediated Tempo-Oxidized Nano Cellulose Mixed-Matrix Membranes, Tony Roller May 2020

Analysis Of Blood Purification Studies On Oxone Mediated Tempo-Oxidized Nano Cellulose Mixed-Matrix Membranes, Tony Roller

Biomedical Engineering Undergraduate Honors Theses

End-stage renal disease (ESRD) is currently the ninth leading cause of death in the United States, and of the 661,00 Americans diagnosed with ESRD, approximately 468,800 were on hemodialysis in 2016. Hemodialysis refers to a technique where a machine combined with a membrane, often referred to as an artificial kidney, is used to clean blood by removing any waste such as urea, potassium, and other smaller waste products while preserving the concentrations and integrity of cells and proteins in the blood. It has been shown in artificial blood studies that cellulose nanomaterials, like TEMPO/Oxidized cellulose nanoparticles (TOCNs), can be integrated …