Open Access. Powered by Scholars. Published by Universities.®
Biomedical Engineering and Bioengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Biomedical Engineering and Bioengineering
An Investigation Of The Applicability Of Sugar And Wax Valves For Rapid Molecular Diagnostics, Rui Shen, Jacqueline C. Linnes
An Investigation Of The Applicability Of Sugar And Wax Valves For Rapid Molecular Diagnostics, Rui Shen, Jacqueline C. Linnes
The Summer Undergraduate Research Fellowship (SURF) Symposium
Paper-based Loop-mediated Isothermal Amplification (LAMP) of nucleic acids is a low-cost molecular diagnostic method to detect biological pathogens and has been successfully combined with lateral flow devices. This invention is a low-cost visual detection technique of various disease. However, existing assays require multiple user-activated steps and are relatively complicated to use at the point of care due to steps like the heating process. This project aimed to investigate an ideal valve for integrating LAMP onto the lateral flow assay. An ideal valve needs to be able to stop the fluid flow for 20-60 minutes under 65 degree to complete the …