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Biomedical Engineering and Bioengineering Commons™
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- Gait (2)
- Rehabilitation (2)
- Stroke (2)
- Adaptive Optics (1)
- Balance (1)
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- Biplane (1)
- Bone fragility (1)
- Cast Materials (1)
- Clubfoot (1)
- Complex-valued correlation (1)
- Connectivity (1)
- FMRI (1)
- Fluoroscopy (1)
- Fracture toughness (1)
- Hindfoot (1)
- Human Activity Recognition (1)
- Image Processing (1)
- Intracortical vascular porosity (1)
- Kinematics (1)
- Material Testing (1)
- Micro-computed tomography (1)
- Osteocyte (1)
- Osteogenesis imperfecta (1)
- Photoreceptors (1)
- Plasticity (1)
- Ponseti Method (1)
- Remote Monitoring System (1)
- Retina (1)
- SMS (1)
- Sensorimotor (1)
Articles 1 - 9 of 9
Full-Text Articles in Biomedical Engineering and Bioengineering
Markerless Kinematics Of Pediatric Manual Wheelchair Mobility, Jacob Robert Rammer
Markerless Kinematics Of Pediatric Manual Wheelchair Mobility, Jacob Robert Rammer
Dissertations (1934 -)
Pediatric manual wheelchair users face substantial risk of orthopaedic injury to the upper extremities, particularly the shoulders, during transition to wheelchair use and during growth and development. Propulsion strategy can influence mobility efficiency, activity participation, and quality of life. The current forefront of wheelchair biomechanics research includes translating findings from adult to pediatric populations, improving the quality and efficiency of care under constrained clinical funding, and understanding injury mechanisms and risk factors. Typically, clinicians evaluate wheelchair mobility using marker-based motion capture and instrumentation systems that are precise and accurate but also time-consuming, inconvenient, and expensive for repeated assessments. There is …
A Fourier Description Of Covariance, And Separation Of Simultaneously Encoded Slices With In-Plane Acceleration In Fmri, Mary C. Kociuba
A Fourier Description Of Covariance, And Separation Of Simultaneously Encoded Slices With In-Plane Acceleration In Fmri, Mary C. Kociuba
Dissertations (1934 -)
Functional magnetic resonance imaging (fMRI) studies aim to identify localized neural regions associated with a cognitive task performed by the subject. An indirect measure of the brain activity is the blood oxygenation level dependent (BOLD) signal fluctuations observed within the complex-valued spatial frequencies measured over time. The standard practice in fMRI is to discard the phase information after image reconstruction, even with evidence of biological task-related change in the phase time-series. In the first aim of this dissertation, a complex-valued time-series covariance is derived as a linear combination of second order temporal Fourier frequency coefficients. As opposed to magnitude-only analysis, …
Structural-Functional Brain Connectivity Underlying Integrative Sensorimotor Function After Stroke, Benjamin Thomas Kalinosky
Structural-Functional Brain Connectivity Underlying Integrative Sensorimotor Function After Stroke, Benjamin Thomas Kalinosky
Dissertations (1934 -)
In this dissertation research project, we demonstrated the relationship between the structural and functional connections across the brain in stroke survivors. We used this information to predict arm function in stroke survivors, suggesting that the tools developed through this research will be useful for prescribing individualized rehabilitation strategies in people after stroke. Current clinical methods for rehabilitating sensorimotor function after stroke are not based on the locus of injury in the brain. Instead, therapies are generalized, treating symptoms such as weakness and spasticity. This results in outcomes that are highly variable, with severity of impairment immediately following stroke as the …
Noninvasive Assessment Of Photoreceptor Structure And Function In The Human Retina, Robert Francis Cooper
Noninvasive Assessment Of Photoreceptor Structure And Function In The Human Retina, Robert Francis Cooper
Dissertations (1934 -)
The human photoreceptor mosaic underlies the first steps of vision; thus, even subtle defects in the mosaic can result in severe vision loss. The retina can be examined directly using clinical tools; however these devices lack the resolution necessary to visualize the photoreceptor mosaic. The primary limiting factor of these devices is the optical aberrations of the human eye. These aberrations are surmountable with the incorporation of adaptive optics (AO) to ophthalmoscopes, enabling imaging of the photoreceptor mosaic with cellular resolution. Despite the potential of AO imaging, much work remains before this technology can be translated to the clinic. Metrics …
Biomechanical Characerization And Evaluation Of Conservative Clubfoot Correction, Tamara Loren Cohen
Biomechanical Characerization And Evaluation Of Conservative Clubfoot Correction, Tamara Loren Cohen
Dissertations (1934 -)
Congential talipes equinovarus, or clubfoot, affects approximately 200,000 newborns worldwide each year and presents with equinovarus of the hindfoot, as well as cavus and adduction of the midfoot. In addition to bone malformation and displacement, soft tissue contractures encapsulate the medial and posterior aspects of the affected foot. The Ponseti method is a conservative treatment that progressively repositions the clubfoot through weekly casting, followed by bracing. Concerns exist regarding the variability in outcomes, resistance to treatment, and risk of relapse, which occur in approximately 10% of the population. Potential factors contributing to variability and resistant clubfoot include cast material performance, …
Computational Approaches For Remote Monitoring Of Symptoms And Activities, Ferdaus Kawsar
Computational Approaches For Remote Monitoring Of Symptoms And Activities, Ferdaus Kawsar
Dissertations (1934 -)
We now have a unique phenomenon where significant computational power, storage, connectivity, and built-in sensors are carried by many people willingly as part of their life style; two billion people now use smart phones. Unique and innovative solutions using smart phones are motivated by rising health care cost in both the developed and developing worlds. In this work, development of a methodology for building a remote symptom monitoring system for rural people in developing countries has been explored. Design, development, deployment, and evaluation of e-ESAS is described. The system’s performance was studied by analyzing feedback from users. A smart phone …
Biplanar Fluoroscopic Analysis Of In Vivo Hindfoot Kinematics During Ambulation, Janelle Ann Cross
Biplanar Fluoroscopic Analysis Of In Vivo Hindfoot Kinematics During Ambulation, Janelle Ann Cross
Dissertations (1934 -)
The overall goal of this project was to develop and validate a biplanar fluoroscopic system and integrated software to assess hindfoot kinematics. Understanding the motion of the foot and ankle joints may lead to improved treatment methods in persons with foot and ankle pathologies. During gait analysis, skin markers are placed on the lower extremities, which are defined as four rigid-body segments with three joints representing the hip, knee and ankle. This method introduces gross assumptions on the foot and severely limits the analysis of in depth foot mechanics. Multi-segmental models have been developed, but are susceptible to skin motion …
Characterization Of Bone Material Properties And Microstructure In Osteogenesis Imperfecta/Brittle Bone Disease, John Robert Jameson
Characterization Of Bone Material Properties And Microstructure In Osteogenesis Imperfecta/Brittle Bone Disease, John Robert Jameson
Dissertations (1934 -)
Osteogenesis imperfecta (OI) is a genetic disorder primarily associated with mutations to type I collagen and resulting in mild to severe bone fragility. To date, there is very little data quantifying OI cortical bone mechanics. The purpose of this dissertation was to investigate bone microstructure, mineralization, and mechanical properties in adolescents with OI. Characterization studies were performed on small osteotomy specimens obtained from the extremities during routine corrective surgeries. Nanoindentation was used to examine the longitudinal elastic modulus and hardness at the material level for mild OI type I vs. severe OI type III. Both modulus and hardness were significantly …
Dynamic Balance Control During Treadmill Walking In Chronic Stroke Survivors, Eric Richard Walker
Dynamic Balance Control During Treadmill Walking In Chronic Stroke Survivors, Eric Richard Walker
Dissertations (1934 -)
Maintaining dynamic balance is an important component of walking function that is likely impaired in chronic stroke survivors, evidenced by an increased prevalence of falls. Dynamic balance control requires maintaining the center of mass (COM) within the base of support during movement. During walking, dynamic balance control is achieved largely by modifying foot placement to adjust the base of support. However, chronic stroke survivors have difficulty with both precision control of foot placement, as well as reduced control of COM movement. The objective of this dissertation was to characterize dynamic balance control strategies during walking in chronic stroke survivors. Additionally, …