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Biomedical Engineering and Bioengineering Commons

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Biomedical Devices and Instrumentation

California Polytechnic State University, San Luis Obispo

Master's Theses

COMSOL

Publication Year

Articles 1 - 2 of 2

Full-Text Articles in Biomedical Engineering and Bioengineering

Analysis Of Particles Thorough The Aortic Arch During Transcatheter Aortic Valve Replacement, Andrew Joseph Janicki Jun 2015

Analysis Of Particles Thorough The Aortic Arch During Transcatheter Aortic Valve Replacement, Andrew Joseph Janicki

Master's Theses

Ischemia caused by particles becoming dislodged during transcatheter aortic valve replacement (TAVR) is a possible complication of TAVR. The particles that become dislodged can travel out of the aortic valve, into the aortic arch, and then into either the brachiocephalic artery, the left common carotid artery, the left subclavian artery or continue into the descending aorta. If the particles continue into the descending aorta it poses no risk of causing ischemia however if it travels into the other arteries then it increases the possibility of the particle causing an ischemic event. The goal of this study is to determine what …


Hydrodynamic Focused Passive Separation Under Continuous Flow In A Microfluidic Chip, Jad Kanbar Sep 2012

Hydrodynamic Focused Passive Separation Under Continuous Flow In A Microfluidic Chip, Jad Kanbar

Master's Theses

A continuous flow, passive separation device was designed using an equivalent circuit to create variable flow rates for hydrodynamic focusing to drain channels and collection outlets. By varying the diameter of the sample inlet connection into the reservoir, the particle position was influenced significantly, which enabled desired separations. Additionally it was noted that the relative, horizontal position of the inlet also had a significant influence on particle position within the device. A dimensionless number, the Characteristic Sample Inlet, was developed to relate geometric properties of the inlet reservoir to downstream particle distribution. It was found that a 2:1 ratio between …