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Full-Text Articles in Biomedical Engineering and Bioengineering
Alternating Current Electrokinetics Based Capacitive Affinity Biosensor: A Point-Of-Care Diagnostic Platform, Haochen Cui
Alternating Current Electrokinetics Based Capacitive Affinity Biosensor: A Point-Of-Care Diagnostic Platform, Haochen Cui
Doctoral Dissertations
Capacitive bioaffinity detection using microelectrodes is considered as a promising label-free method for point-of-care diagnosis, though with challenges in sensitivity, specificity and the time “from sample to result.” This work presents an alternating current (AC)-electrokinetic based capacitive affinity sensing method that is capable of realizing rapid in-situ detection of specific biomolecular interactions such as probe-analyte binding. The capacitive biosensor presented here employs elevated AC potentials at a fixed frequency for impedimetric interrogation of the microelectrodes. Such an AC signal is capable of inducing dielectrophoresis (DEP) and AC electrothermal (ACET) effects, so as to realize in-situ enrichment of macro and even …
A Magnetic Actuated Fully Insertable Robotic Camera System For Single Incision Laparoscopic Surgery, Xiaolong Liu
A Magnetic Actuated Fully Insertable Robotic Camera System For Single Incision Laparoscopic Surgery, Xiaolong Liu
Doctoral Dissertations
Minimally Invasive Surgery (MIS) is a common surgical procedure which makes tiny incisions in the patients anatomy, inserting surgical instruments and using laparoscopic cameras to guide the procedure. Compared with traditional open surgery, MIS allows surgeons to perform complex surgeries with reduced trauma to the muscles and soft tissues, less intraoperative hemorrhaging and postoperative pain, and faster recovery time. Surgeons rely heavily on laparoscopic cameras for hand-eye coordination and control during a procedure. However, the use of a standard laparoscopic camera, achieved by pushing long sticks into a dedicated small opening, involves multiple incisions for the surgical instruments. Recently, single …