Open Access. Powered by Scholars. Published by Universities.®
Biomedical Engineering and Bioengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 3 of 3
Full-Text Articles in Biomedical Engineering and Bioengineering
Mechanical Properties Of Bone Due To Sost Expression: Nanoindentation Assessment Of Murine Femurs, Amir Rafie
Mechanical Properties Of Bone Due To Sost Expression: Nanoindentation Assessment Of Murine Femurs, Amir Rafie
Master's Theses
In the human genome, the SOST gene codes for a protein sclerostin. Sclerostin is an osteocyte-expressed negative regulator of bone formation. When the SOST gene is not coded, bone formation is reduced in individuals during skeletal maturation. This study utilizes nanoindentation methods to test for the mechanical properties of bones that both express and do not express the SOST gene. 100 transgenic murine femurs were obtained from Lawrence Livermore Labs in the form of 6 and 8 month SOST transgenic mice, 6 and 12 month SOST knockout mice, and wild type control littermates for each of the 4 age groups. …
Modeling The Zimmer Fitmore And Ml Taper Implantation, Tyler Kazuo Franklin
Modeling The Zimmer Fitmore And Ml Taper Implantation, Tyler Kazuo Franklin
Master's Theses
With more young adults requiring total hip
arthroplasties the need for bone saving implants becomes
more important. The Zimmer Fitmore is a new bone saving
implant that utilizes an implantation technique that
reduces the damage to the muscle tissue allowing for
patients to have a short recovery time as well as a new
design that allows it to rest on the medial cortex. There
has been anecdotal evidence that this device leads to early
revision within six months of implantation due to failures
occurring in the medial cortex. The main goal of this
study was to computationally model the Zimmer …
Bacterial Growth On Metal And Non-Metal Surfaces In A Static Bioreactor, Rolan Yuk Loong Liong
Bacterial Growth On Metal And Non-Metal Surfaces In A Static Bioreactor, Rolan Yuk Loong Liong
Master's Theses
Research was conducted to observe bacterial growth on the surface of metals in a static bioreactor. Metal and non-metal samples were subjected to bacterial exposure (1 day and 9 days). The metal samples were surface treated prior to bacterial exposure. The microstructures of the surface treated samples were analyzed by optical microscopy. After exposure, the microstructures of the samples were analyzed by scanning electron microscopy (SEM). The analysis suggested that microbial attachment on the surface was related to the underlying microstructure of steel. The preferential attachment of microbes could potentially be influenced by cathodic and anodic regions created by the …