Biomedical Engineering and Bioengineering Commons^™

Developing And Characterizing A Novel Tempo Cnf Hydrogel Adjuvant And Delivery System For Aquatic Vaccines, Kora Kukk

Electronic Theses and Dissertations

Aquaculture is a large part of the food production sector which is greatly expanding. One of the largest losses in aquaculture is due to pathogens. Current solutions for protecting farmed finfish from pathogens can be very expensive with variable efficiency. Current disease prevention strategies include vaccination. Types of vaccines include immersion vaccines, feed vaccines, and injectable vaccines. The most popular solution is oil-based injectable vaccines due to its protection. However, the oil-based adjuvant used in most of these formulations causes adverse reactions in the fish including reduced growth. These vaccines require multiple administrations throughout the fish’s lifetime causing unwanted handling …