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Biomedical Engineering and Bioengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Keyword
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- 5-fluorouracil anti-cancer drug (1)
- Adipose-derived stem/stromal cells (1)
- Band gap (1)
- Cell-based therapy (1)
- Drug delivery (1)
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- Electrospinning. (1)
- Freeze-thaw (1)
- Galectin-3 (1)
- Inflammation (1)
- Integrin-binding peptides (1)
- Laboratory test (1)
- Magnetic ferrite-encapsulated titania nanotube arrays (1)
- N-methacrylate glycol chitosan hydrogel (1)
- Peripheral artery disease (1)
- Photoconvesion efficiency (1)
- Photoelctrochemical properties (1)
- Poly (vinyl alcohol) cryogel (1)
- Re-epithelialization (1)
- Reference shear modulus (1)
- Scaffold (1)
- Scaffold-based cell-delivery system (1)
- Shear modulus (1)
- Shear wave velocity (1)
- Small strain (1)
- Stress-strain (1)
- Tissue-mimicking construct (1)
- Titania nanotube arrays (1)
- Wound Healing (1)
Articles 1 - 5 of 5
Full-Text Articles in Biomedical Engineering and Bioengineering
Fabrication And Modification Of Titania Nanotube Arrays For Harvesting Solar Energy And Drug Delivery Applications, Ahmed El Ruby Abdel Rahman Mohamed
Fabrication And Modification Of Titania Nanotube Arrays For Harvesting Solar Energy And Drug Delivery Applications, Ahmed El Ruby Abdel Rahman Mohamed
Electronic Thesis and Dissertation Repository
The fast diminishing of fossil fuels in the near future, as well as the global warming caused by increasing greenhouse gases have motivated the urgent quest to develop advanced materials as cost-effective photoanodes for solar light harvesting and many other photocatalytic applications. Recently, titania nanotube arrays (TNTAs) fabricated by anodization process has attracted great interest due to their excellent properties such as: high surface area, vertically oriented, highly organized, one-dimensional, nanotubular structure, photoactivity, chemical stability and biocompatibility. This unique combination of excellent properties makes TNTAs an excellent photoanode for solar light harvesting. However, the relatively wide band gap energy of …
Design And Validation Of Delivery Systems For Galectin-3 For Skin Healing Applications, Karrington A. Mcleod
Design And Validation Of Delivery Systems For Galectin-3 For Skin Healing Applications, Karrington A. Mcleod
Electronic Thesis and Dissertation Repository
Chronic wounds present a significant burden to patients, causing pain, impairing limb function, and often resulting in the need for amputation. Treatment of chronic dermal wounds is challenging, with current therapies showing limited efficacy in clinical trials. As galectin-3 has been implicated in several wound healing processes, its efficacy as a therapeutic in skin healing was investigated in this study. An electrospun gelatin scaffold loaded with galectin-3 was developed as a delivery system. The influence of human recombinant galectin-3 in skin healing, when delivered topically and using an electrospun scaffold, was then investigated in wild type and diabetic mice. Electrospun …
Assessment Of The Non-Linear Stress-Strain Characteristics Of Poly (Vinyl Alcohol) Cryogel, Mojdeh Zakeri
Assessment Of The Non-Linear Stress-Strain Characteristics Of Poly (Vinyl Alcohol) Cryogel, Mojdeh Zakeri
Electronic Thesis and Dissertation Repository
Creation of tissue-mimicking constructs is of great importance in the field of biomedical engineering. Poly (vinyl Alcohol) (PVA) is a biomaterial capable of simulating a wide range of geometries and mechanical properties of biological tissues. It is nontoxic, biocompatible, and easy to produce. PVA can be physically crosslinked by repeated cycles of freezing and thawing. The final product of this process is called PVA cryogel (PVA-C). The mechanical properties of PVA-C can be accurately controlled by changing PVA molecular weight, PVA concentration, and number and duration of freeze/thaw cycles (FTC). In this study, the stress-strain behavior of PVA cryogel was …
Investigation Of Chitosan-Based Hydrogels As A Cell Delivery Platform For Adipose-Derived Stem/Stromal Cell Transplantation To Promote Angiogenesis In Ischemic Tissues, Jobanpreet Singh Dhillon
Investigation Of Chitosan-Based Hydrogels As A Cell Delivery Platform For Adipose-Derived Stem/Stromal Cell Transplantation To Promote Angiogenesis In Ischemic Tissues, Jobanpreet Singh Dhillon
Electronic Thesis and Dissertation Repository
Stem cell transplantation is under investigation to stimulate angiogenesis in patients with peripheral artery disease. To develop a cell-delivery platform that enhances cell retention and function post-transplantation, the response of human adipose-derived stem/stromal cells (ASCs) encapsulated within N-methacrylate glycol chitosan (MGC) hydrogels with or without integrin-binding RGD or IKVAV motifs was explored. ASC viability was enhanced in the MGC and MGC-RGD hydrogels relative to the MGC-IKVAV group under hypoxic (2% O2) culture conditions, with cell spreading and higher metabolic activity noted in MGC-RGD at 14 days. Analysis of angiogenic gene expression revealed similar patterns between all hydrogel …
Effect Of L-Ascorbic Acid And All-Trans Retinoic Acid On Smooth Muscle Cells Cultured On Pcl Scaffolds, Brandon Chaffay
Effect Of L-Ascorbic Acid And All-Trans Retinoic Acid On Smooth Muscle Cells Cultured On Pcl Scaffolds, Brandon Chaffay
Electronic Thesis and Dissertation Repository
The aim of vascular tissue engineering (VTE) is to fabricate tissues that are both mechanically and biologically competent similar to the native vessel they are intended to replace. To this end, the incorporation of sufficient extracellular matrix elastin and collagen is important. The objective of this thesis work was to evaluate the effect of two biochemical factors, l-ascorbic acid (AA) and all-trans retinoic acid (atRA), on elastin synthesis when coronary artery smooth muscle cells were cultured on 3D polycaprolactone (PCL) scaffolds. First, porous PCL scaffolds were fabricated using a solvent casting and particulate leaching approach. The effect of different …