Open Access. Powered by Scholars. Published by Universities.®
Biomedical Engineering and Bioengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Keyword
-
- Droplet interface bilayer (2)
- Biofuel production (1)
- Biomass (1)
- Biomimetic model (1)
- Biomimetics (1)
-
- Blade strike impact (1)
- Clostridium thermocellum (1)
- Consolidated bioprocessing (1)
- Directed evolution (1)
- Doppler (1)
- Droplet interface bilayers (1)
- Femtosecond laser machining (1)
- Functionalization (1)
- Gait Analysis (1)
- Hydrogen (1)
- Hydropower (1)
- Integrin (1)
- LFA-1 I-domain (1)
- Lipid bilayer (1)
- Lipids self-assembly (1)
- Liquid interface (1)
- Metabolic engineering (1)
- Microbial community (1)
- Microbial electrolysis (1)
- Microfluidics (1)
- Model membrane (1)
- Mortality (1)
- Nanofabrication (1)
- Non-Contact Techniques (1)
- Photoplethysmography (1)
Articles 1 - 10 of 10
Full-Text Articles in Biomedical Engineering and Bioengineering
Non-Contact Techniques For Human Vital Sign Detection And Gait Analysis, Farnaz Foroughian
Non-Contact Techniques For Human Vital Sign Detection And Gait Analysis, Farnaz Foroughian
Doctoral Dissertations
Human vital signs including respiratory rate, heart rate, oxygen saturation, blood pressure, and body temperature are important physiological parameters that are used to track and monitor human health condition. Another important biological parameter of human health is human gait. Human vital sign detection and gait investigations have been attracted many scientists and practitioners in various fields such as sport medicine, geriatric medicine, bio-mechanic and bio-medical engineering and has many biological and medical applications such as diagnosis of health issues and abnormalities, elderly care and health monitoring, athlete performance analysis, and treatment of joint problems. Thoroughly tracking and understanding the normal …
Susceptibility Of Riverine Fishes To Anthropogenically-Linked Trauma: Strikes From Hydropower Turbine Blades, Ryan K. Saylor
Susceptibility Of Riverine Fishes To Anthropogenically-Linked Trauma: Strikes From Hydropower Turbine Blades, Ryan K. Saylor
Doctoral Dissertations
Hydropower accounts for nearly 40% of renewable electricity generation in the US; however, dams significantly impact the surrounding aquatic ecosystems. One of the most visible impacts of hydropower―beyond the dam itself―is the direct negative impacts (injury or death) to fish populations that must pass through hydropower turbines to access desired downstream habitat. During passage, fishes face many potential stressors that can cause severe injuries and often leads to high rates of mortality. In this dissertation, I have focused on quantifying how fishes respond to impacts from turbine blades that may occur during turbine passage. Laboratory research into blade strike impact …
Engineered Switch Protein Inspired By Novel Protein Affinity Transition Mode, Liang Fang
Engineered Switch Protein Inspired By Novel Protein Affinity Transition Mode, Liang Fang
Doctoral Dissertations
Many natural proteins involved in complex biological processes such as ligand binding and protein folding demonstrate multiple, allosterically-regulated conformational states, with protein activity regulated by effector molecules. The alpha L integrin and its inserted domain (I domain) is one example of such a protein. The binding of the effector molecule such as talin or filamin to the cytoplasmic domain of the integrin increases the binding affinity between I- domain and its ligand intercellular adhesion molecule-1, known as ICAM-1.There are multiple models attempting to describe the mechanism responsible for the change in binding affinity. According to research conducted by our lab, …
Engineering Platforms For Advancing Plant Synthetic Biology, Tayler Marie Schimel Mcneillie
Engineering Platforms For Advancing Plant Synthetic Biology, Tayler Marie Schimel Mcneillie
Doctoral Dissertations
This work describes research aimed at adapting advanced engineering systems for plant biotechnology. The droplet interface bilayer (DIB) is a robust and versatile platform for replicating model cell membranes, providing a bottom-up approach for synthetic cell- and tissue-like structures. In this work, a microfluidic device featuring five inlets, one for the continuous oil phase and four discrete aqueous channels for droplet generation was designed. Droplet production rates were controlled by adjusting the applied pressure of each inlet; and thus, altering the droplet sequence for capturing linear DIB networks in a downstream hydrodynamic trapping array. This microfluidic system provides a high-throughput …
Managing Exoelectrogenic Microbial Community Development Through Bioprocess Control For Conversion Of Biomass-Derived Streams, Alex James Lewis
Managing Exoelectrogenic Microbial Community Development Through Bioprocess Control For Conversion Of Biomass-Derived Streams, Alex James Lewis
Doctoral Dissertations
Bioelectrochemical systems are an emerging technology capable of utilizing aqueous waste streams generated during biomass conversion of lignocellulosic feedstocks to produce valuable co-products and thus, have potential to be integrated into biorefineries. In a microbial electrolysis cell, organic compounds are converted to electrons, protons, and CO2 by fermentative and exoelectrogenic bacteria in the anode compartment. By having the ability to extract electrons from waste streams, these systems can treat water while also producing hydrogen, and thus can improve the efficiency of biomass to fuel production by minimizing external hydrogen requirement and enabling water recycle. The overall goal of this …
Characterization And Manipulation Of Lipid Self-Assembly To Construct Stable, Portable Synthetic Lipid Bilayers, Guru Anand Venkatesan
Characterization And Manipulation Of Lipid Self-Assembly To Construct Stable, Portable Synthetic Lipid Bilayers, Guru Anand Venkatesan
Doctoral Dissertations
The overarching goal of this research work is to further our understanding of lipid self-assembly and its organization at an oil-water interface to support the development of synthetic lipid bilayer systems that can be used in biologically relevant fields such as membrane biophysics, protein electrophysiology, development of synthetic biomolecules, drugs, nanoparticles and other applications. Self-assembly kinetics and interfacial properties of lipid monolayers formed at a liquid-air and liquid-liquid interface are characterized using Langmuir-Blodgett trough and pendant drop tensiometer. Insights gained from these studies not only allow us to answer questions related to droplet interface bilayer (DIB; a promising technique to …
In Silico Driven Metabolic Engineering Towards Enhancing Biofuel And Biochemical Production, Richard Adam Thompson
In Silico Driven Metabolic Engineering Towards Enhancing Biofuel And Biochemical Production, Richard Adam Thompson
Doctoral Dissertations
The development of a secure and sustainable energy economy is likely to require the production of fuels and commodity chemicals in a renewable manner. There has been renewed interest in biological commodity chemical production recently, in particular focusing on non-edible feedstocks. The fields of metabolic engineering and synthetic biology have arisen in the past 20 years to address the challenge of chemical production from biological feedstocks. Metabolic modeling is a powerful tool for studying the metabolism of an organism and predicting the effects of metabolic engineering strategies. Various techniques have been developed for modeling cellular metabolism, with the underlying principle …
Improving Droplet Interface Bilayers As Models For Cell Membranes, Graham Jeffery Taylor
Improving Droplet Interface Bilayers As Models For Cell Membranes, Graham Jeffery Taylor
Doctoral Dissertations
This work describes research aimed at improving the droplet interface bilayer (DIB) platform for creating and characterizing biologically relevant model cell membranes. Improvements are made possible in part through the development of a portable, compact platform for controlling temperature with DIBs. Feedback-controlled heating allows studies to be conducted across a range of temperatures, from ambient up to at least 80°C, and also provides new understanding of methods to form DIBs using mixtures of total lipids extracted from bacterial and eukaryotic cells. The membranes formed from total lipid extracts (TLE) are introduced along with evidence that model membranes formed using lipid …
Femtosecond Laser Patterned Templates And Imprinted Polymer Structures, Deepak Rajput
Femtosecond Laser Patterned Templates And Imprinted Polymer Structures, Deepak Rajput
Doctoral Dissertations
Femtosecond laser machining is a direct-write lithography technique by which user-defined patterns are efficiently and rapidly generated at the surface or within the bulk of transparent materials. When femtosecond laser machining is performed with tightly focused amplified pulses in single-pulse mode, transparent substrates like fused silica can be surface patterned with high aspect ratio (>10:1) and deep (>10 μm) nanoholes. The main objective behind this dissertation is to develop single-pulse amplified femtosecond laser machining into a novel technique for the production of fused silica templates with user-defined patterns made of high aspect ratio nanoholes. The size of the …
Modification And Evaluation Of Continuous Roll Prediction Model For Front Drive Mowers, Xinyan Wang
Modification And Evaluation Of Continuous Roll Prediction Model For Front Drive Mowers, Xinyan Wang
Doctoral Dissertations
The recently approved ASAE Standard S547 “Tip-Over Protective Structure (TOPS) for Front Wheel Drive Turf and Landscape Equipment” addressed a continuous roll prediction model for Roll-Over Protective Structure (ROPS) design. The existing model described in this Standard did not take into account the influence of the mower deck on the rollover behavior. In order to evaluate the accuracy of the original model, according to the ASAE S547 requirement, a 4.05 meters long and 3.42 meters wide slope of 35 degrees was constructed at the University of Tennessee. Lateral upset tests for Deere F925 front drive mower with regular and inverted …