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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Simultaneous Estimation And Segmentation Of T1 Map For Breast Parenchyma Measurement, Ye Xing, Yangming Ou, Sarah Englander, Mitchell D. Schnall, Dinggang Shen
Simultaneous Estimation And Segmentation Of T1 Map For Breast Parenchyma Measurement, Ye Xing, Yangming Ou, Sarah Englander, Mitchell D. Schnall, Dinggang Shen
Sarah Englander
Breast density has been shown to be an independent risk factor for breast cancer. In order to segment breast parenchyma, which has been proposed as a biomarker of breast cancer risk, we present an integrated algorithm for simultaneous T1 map estimation and segmentation, using a series of magnetic resonance (MR) breast images. The advantage of using this algorithm is that the step of T1 map estimation (E-Step) and the step of T1 map based tissue segmentation (S-Step) can benefit each other. Since the estimated T1 map can be noisy due to the complexity of T1 estimation method, the tentative tissue …
Terahertz Imaging For Cancer Detection, Benjamin A. St. Peter
Terahertz Imaging For Cancer Detection, Benjamin A. St. Peter
Masters Theses 1911 - February 2014
This project evaluates the ability of terahertz (THz) radiation to differentiate cancerous from non-cancerous human breast lumpectomy and mastectomy tissue. This is done by aiming a narrow-band THz beam at medical samples and measuring reflected power. THz images of specimens from Breast Conservation Surgery (BCS) were created using a gas laser source and mechanical scanning. The design and characterization of this system is discussed in detail. The images were correlated with optical histological micrographs of the same specimens and discrimination values of more than 70% were found for five of the six samples using Receiver Operating Characteristic (ROC) analysis.