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Full-Text Articles in Biomedical Engineering and Bioengineering
Using Computer Vision To Track Anatomical Structures During Cochlear Implant Surgery, Nicholas Bach
Using Computer Vision To Track Anatomical Structures During Cochlear Implant Surgery, Nicholas Bach
McKelvey School of Engineering Theses & Dissertations
There is a steep learning curve for surgeons performing cochlear implant surgeries. We aimed to use computer vision to track anatomical features with the goal of helping surgeons perform cochlear implant surgery without damaging the cochlea. We compared nine algorithms in total, seven object tracking algorithms and two optical flow algorithms utilizing the LucasKanade method, on manually created cochlear implant surgery videos to determine the accuracy associated with each. Compared with eight other algorithms, we observed that an iterative pyramidal implementation of the Lucas-Kanade (IPLK) method, implemented through OpenCV, performed the best. The IPLK method had the lowest error rate …
Injectable Ct/Mri Contrast Agent For Gastrointestinal Tumor Tracking, Luna Zhang
Injectable Ct/Mri Contrast Agent For Gastrointestinal Tumor Tracking, Luna Zhang
McKelvey School of Engineering Theses & Dissertations
Gastrointestinal cancers remain to be of the most common and deadly cancers worldwide. Early detection and treatments are crucial for reducing mortality and improving patient outcome. Radiation therapy is a non-invasive localized tumor treatment method, and utilizes radiation to kill the cancerous cells and shrink tumors at specific sites. Precise localization at the target tumor site is therefore important before radiation therapy, especially for gastrointestinal tumor sites located in the moving bowel. Currently, invasive endoscopies along with ink tattoos are used for identifying tumor location, which often require sedation and bring much discomfort. Imaging tests, including CT and MRI, play …
Focused Ultrasound-Mediated Drug Delivery To The Brainstem, Dezhuang Ye
Focused Ultrasound-Mediated Drug Delivery To The Brainstem, Dezhuang Ye
McKelvey School of Engineering Theses & Dissertations
Brainstem gliomas are tumors that occur in the brainstem, the brain region that connects the brain to the spinal cord and controls vital body functions. The critical anatomic location of the brainstem precludes surgical intervention and limits the use of invasive therapeutic techniques. Moreover, the frequently intact blood-brain barrier (BBB) of most brainstem gliomas prevents therapeutic agents from reaching the diseased site. The currently available techniques for brain drug delivery are either invasive (e.g., convection-enhanced delivery) or lack targeting to the diseased site (e.g., intranasal brain drug delivery). Novel techniques that can noninvasively overcome the BBB are critically needed for …