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Biomedical Engineering and Bioengineering Commons™
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Bioimaging and Biomedical Optics
Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research
- Keyword
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- Biosensors (1)
- Blood Flow Velocity Measurement and Motion Detection (1)
- Elasticity imaging (1)
- MRE (1)
- MRI (1)
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- Magnetic resonance elastography (1)
- Magnetic resonance imaging (1)
- Medical Ultrasound Imaging (1)
- Morphometrics (1)
- Nanotechnology (1)
- Oxidative damage (1)
- Peripheral arterial disease (1)
- Raman Spectroscopy (1)
- Shear wave (1)
- Single Walled Carbon Nanotubes (1)
- Speckle Pattern (1)
- Tendon (1)
- Transient elastography (1)
- Two-Dimensional (1)
- Ultrasound (1)
Articles 1 - 5 of 5
Full-Text Articles in Biomedical Engineering and Bioengineering
Preclinical Development Of Single Walled Carbon Nanotube-Based Optical Biosensors, Eric M. Hofferber
Preclinical Development Of Single Walled Carbon Nanotube-Based Optical Biosensors, Eric M. Hofferber
Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research
High resolution, long-term monitoring of key biological analytes would improve patient outcomes by providing earlier detection of disease states and improved efficacy of treatment. One class of biosensors that have gained much attention in recent years are optical biosensors. Optical probes are attractive biosensors due to their noninvasive nature of detection, as certain light can pass through tissue, water, and blood. Single walled carbon nanotubes (SWNT) are a specific type of optical biosensor that fluoresce in the near infrared range of the electromagnetic spectrum and offer unparalleled spatial and temporal resolution. SWNT have been applied as biosensors in vitro, …
Applications Of Novel Mri Technologies In Tissue Engineering And Disease Diagnosis, Vahid Khalilzad-Sharghi
Applications Of Novel Mri Technologies In Tissue Engineering And Disease Diagnosis, Vahid Khalilzad-Sharghi
Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research
Magnetic resonance imaging (MRI) and magnetic resonance elastography (MRE) are increasingly under investigation to explore their potential role in establishing effective evaluation methods for the procedure of tissue regeneration carried out in vitro, in vivo, and in disease diagnosis. To this end, there is a continuous pursuit of novel tools both in vitro and in vivo. For instance, there is a great need for the development and evaluation of an MR-compatible incubation system that enables simultaneous monitoring and culturing of cell and tissue constructs using MRI techniques. Such an imagingcompatible incubation system eliminates exposing the culture to the risks of …
Morphometric, Biochemical, And Raman Spectral Analyses Of Muscle Damage In Patients With Peripheral Arterial Disease: Providing Objective Criteria For Diagnosis And Treatment Monitoring, Kim Cluff
Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research
Peripheral arterial disease (PAD), which affects approximately 10 million Americans, is characterized by atherosclerosis of the non-coronary arteries. PAD produces a progressive accumulation of ischemic injury to the limbs that is reflected in a gradual worsening in the myofiber morphology and oxidative damage in the gastrocnemius muscle. In this study, we evaluated the hypothesis that quantitative morphological and biochemical parameters of gastrocnemius myofibers change in a consistent manner during the progression of PAD, provide an objective grading of muscle degeneration in the ischemic limb, and correlate to clinical stage of PAD. Myofiber morphometrics were determined precisely with mathematical equations that …
Two-Dimensional Blood Flow Velocity Estimation Using Ultrasound Speckle Pattern Dependence On Scan Direction And Velocity, Tiantian Xu
Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research
Cardiovascular disease is the leading cause death in the United States. Although emergency surgery and medicine can be used for cardiovascular disease treatment, the survivors will suffer for it afterwards. Ultrasound blood flow measurement provides a noninvasive way for cardiovascular diseases diagnosis. In this dissertation, three algorithms for blood flow velocity measurements were investigated and optimized. Feature tracking has been previously proposed for vector velocity measurement. In Chapter 3, the optimal amplitude and time thresholds for feature extraction were investigated to minimize flow estimate variance while providing sufficient spatial and temporal coverage of flow area. A new method of lateral …
Ultrasound Transient Shear Wave Elasticity Imaging For Tendon Tissue, Pengfei Song
Ultrasound Transient Shear Wave Elasticity Imaging For Tendon Tissue, Pengfei Song
Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research
Degeneration of tendon tissue is a common cause of tendon dysfunction with the symptoms of repeated episodes of pain and palpable increase of tendon thickness. Tendon mechanical properties are directly related to its physiological composition and the structural organization of the interior collagen fibers which could be altered by tendon degeneration due to overuse or injury. Thus, measuring mechanical properties of tendon tissue may represent a quantitative measurement of pain, reduced function, and tissue health. Ultrasound elasticity imaging has been developed in the last two decades and has proved to be a promising tool for tissue elasticity imaging. To date, …