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Biomedical Engineering and Bioengineering Commons

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Bioimaging and Biomedical Optics

Sarah Englander

2012

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Full-Text Articles in Biomedical Engineering and Bioengineering

Simultaneous Estimation And Segmentation Of T1 Map For Breast Parenchyma Measurement, Ye Xing, Yangming Ou, Sarah Englander, Mitchell D. Schnall, Dinggang Shen Feb 2012

Simultaneous Estimation And Segmentation Of T1 Map For Breast Parenchyma Measurement, Ye Xing, Yangming Ou, Sarah Englander, Mitchell D. Schnall, Dinggang Shen

Sarah Englander

Breast density has been shown to be an independent risk factor for breast cancer. In order to segment breast parenchyma, which has been proposed as a biomarker of breast cancer risk, we present an integrated algorithm for simultaneous T1 map estimation and segmentation, using a series of magnetic resonance (MR) breast images. The advantage of using this algorithm is that the step of T1 map estimation (E-Step) and the step of T1 map based tissue segmentation (S-Step) can benefit each other. Since the estimated T1 map can be noisy due to the complexity of T1 estimation method, the tentative tissue …