Biomedical Engineering and Bioengineering Commons^™

Compact Dual Wedge Point Scanning Confocal Reflectance Microscope, William C. Warger Ii, Stephen A. Guerrera, Charles A. Dimarzio

Charles A. DiMarzio

Confocal reflectance microscopy has been shown to provide optical sectioning and resolution sufficient to provide useful information about skin to a depth below the epidermis. However, existing instruments are large and expensive, because of the need for fast twodimensional scanning in the pupil, and the associated relay optics. A more compact scanning system could lead to an affordable hand-held instrument for in vivo imaging. Several approaches are being considered with different advantages and disadvantages. Here we report one approach that incorporates a dual-wedge scanner within a point-scanning configuration. The dual-wedge scanner is implemented by replacing the two scanning mirrors and …