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Full-Text Articles in Biomedical Engineering and Bioengineering

Effect Of Prostaglandin E2 On Mechanical Stresses Applied By Mc3t3-E1 Osteoblast-Like Cells On A Soft Hydrogel Substrate, Abhijit Deb Roy Aug 2011

Effect Of Prostaglandin E2 On Mechanical Stresses Applied By Mc3t3-E1 Osteoblast-Like Cells On A Soft Hydrogel Substrate, Abhijit Deb Roy

Master's Theses

Osteoblasts are sensitive to mechanical stimuli and release Prostaglandin E2 (PGE2) when exposed to a fluid shear stress. The exact mechanism by which these cells sense mechanical stress is not well established. A study of the stresses applied by the osteoblasts, under the influence of PGE2, on a hydrogel provided information regarding intercellular-communication via changes in the substrate surface pattern.

A digital image correlation program was developed using the Levenberg-Marquardt optimization algorithm to analyze images and compare the deformations between pairs of images. Comparisons of images before and after the addition of PE2 to the media showed differences in the …


Near Infrared Imaging System, Barbara Adu-Baffour May 2011

Near Infrared Imaging System, Barbara Adu-Baffour

Honors Scholar Theses

This senior project is to design and fabricate a near infrared imaging system using laser diodes for imaging biological tissues. The device will have three major sections comprising the signal source, detection and data analysis sections.

In the source signal section, a circuit would be designed and built which will contain two laser diodes with different wavelengths (780nm and 830nm). Each of the two laser diodes will modulated at different frequencies to enable a spatial coding system. The detection section of the device will have an optical detector channel which will be designed to detect signals from all the laser …