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Full-Text Articles in Biomedical Engineering and Bioengineering
Biological Effective Dose (Bed) Distribution Matching For Obtaining Brachytherapy Prescription Doses & Dosimetric Optimization For Hybrid Seed Brachytherapy, Jakub Pritz
USF Tampa Graduate Theses and Dissertations
Radioactive seed implant brachytherapy is a common radiotherapy treatment method for prostate cancer. In current clinical practice, a seed consists of a single isotope, such as 125I or 103Pd. A seed containing a mixture of two isotopes has been proposed for prostate cancer treatment. This study investigates a method for defining a prescription dose for new seed compositions based on matching the biological equivalent dose (BED) of a reference plan.
Ten prostate cancer cases previously treated using single isotope seeds (5 using 125I seeds and 5 using 103Pd seeds) were selected for this study. Verification of …