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Full-Text Articles in Aerospace Engineering
Nebulizer-Based Systems To Improve Pharmaceutical Aerosol Delivery To The Lungs, Benjamin M. Spence
Nebulizer-Based Systems To Improve Pharmaceutical Aerosol Delivery To The Lungs, Benjamin M. Spence
Theses and Dissertations
Combining vibrating mesh nebulizers with additional new technologies leads to substantial improvements in pharmaceutical aerosol delivery to the lungs across therapeutic administration methods. In this dissertation, streamlined components, aerosol administration synchronization, and/or Excipient Enhanced Growth (EEG) technologies were utilized to develop and test several novel devices and aerosol delivery systems. The first focus of this work was to improve the poor delivery efficiency, e.g., 3.6% of nominal dose (Dugernier et al. 2017), of aerosolized medication administration to adult human subjects concurrent with high flow nasal cannula (HFNC) therapy, a form of continuous-flow non-invasive ventilation (NIV). The developed Low-Volume Mixer-Heater (LVMH) …
Creation Of Prototype Aircrew Protection Equipment Based On Face Anthropometry, Martin E. Piccus, Gary A. Smith, Brian K. Standley, Tami L. Volk, Linda B. Wildes
Creation Of Prototype Aircrew Protection Equipment Based On Face Anthropometry, Martin E. Piccus, Gary A. Smith, Brian K. Standley, Tami L. Volk, Linda B. Wildes
Theses and Dissertations
The objective of this research is to develop a process which will analyze and group human faces, concentrating on the oxygen mask seal area, into a minimum number of generic yet distinct face types. The shape and size, or form, of the face is described by bending energies. This bending energy provides the features for the grouping of similar face types, while distinguishing representatives for each cluster. The face tariffs are the percentage of faces grouped under a representative face. The representative faces are then transformed Into three-dimensional solids using computer-aided design. A rapid prototype creates the solids or plugs …