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Full-Text Articles in Engineering
Influence Of Natural Convection During Dendritic Array Growth Of Metal Alloys (Gradient Freeze Directional Solidification), Suyog N. Mahajan
Influence Of Natural Convection During Dendritic Array Growth Of Metal Alloys (Gradient Freeze Directional Solidification), Suyog N. Mahajan
ETD Archive
Purpose of this study was to examine the microstructural evolution of primary dendrites during Gradient Freeze Directional Solidification process in cylindrical Pb-5.8% Sb alloy samples to generate the ground- based research data to support a future microgravity experiment on the Space Station in a convection free environment. Pb-5.8Sb was selected for this study because of its ease of processing and availability of physical property data which will be required for predicting the dendrite morphology parameters, such as, primary dendrite spacing and dendrite trunk diameter. This alloy is also susceptible to thermosolutal convection caused by density inversion of the met in …
A Microfluidic Platform To Quantify Spatio-Temporal Diffusion Of Chemo-Gradients Within 3d Scaffolds: Applications In Axonal Biology, Michael A. Sawonik
A Microfluidic Platform To Quantify Spatio-Temporal Diffusion Of Chemo-Gradients Within 3d Scaffolds: Applications In Axonal Biology, Michael A. Sawonik
ETD Archive
Axonal outgrowth and guidance play an important role in wiring the developing and regenerating nervous system. The critical role of biomolecular gradients in facilitating this axonal sensitivity and directionality along specific trajectories needs to be elucidated for designing effective therapeutic treatments under injury or disease conditions. However, previous in vitro approaches based on micropipette assay or gel-turning assay proved to be unsuitable or inefficient for precise generation and quantification of diffusive gradients. In this study, we utilized a microfluidic device to generate and quantify physiologically-relevant biomolecular gradients in a simple and reliable manner. Using a combination of computational and experimental …
One-Dimensional Radial Diffusion Of Small Molecules (376 Da) In Bone Tissue, Kurt W. Farrell
One-Dimensional Radial Diffusion Of Small Molecules (376 Da) In Bone Tissue, Kurt W. Farrell
ETD Archive
The flow of nutrients through any biological tissue is important to maintain homeostasis. If the transport process is understood, medical research teams can better design medications, prosthetic implants, and tissue scaffolds. Additionally, transport rates help physicians to better understand disease states and wound healing, including minor injuries such as breaks and sprains, which will aid in better diagnoses. We developed a novel method that measures the rate of diffusion in vitro, of fluorescein sodium salt. Samples were incubated at 37°C in a 5 CO2 atmosphere for various periods of time. Samples were sliced and analyzed using Image-Pro Plus and MATLAB …
Investigations Of Anatomical Connectivity In The Internal Capsule Of Macaques With Diffusion Magnetic Resonance Imaging, Kyle Andrew Ignatius Taljan
Investigations Of Anatomical Connectivity In The Internal Capsule Of Macaques With Diffusion Magnetic Resonance Imaging, Kyle Andrew Ignatius Taljan
ETD Archive
Understanding anatomical connectivity is crucial for improving outcomes of deep brain stimulation surgery. Tractography is a promising method for noninvasively investigating anatomical connectivity, but connections between subcortical regions have not been closely examined by this method. As many connections to subcortical regions converge at the internal capsule (IC), we investigate the connectivity through the IC to three subcortical nuclei (caudate, lentiform nucleus, and thalamus) in 6 macaques. We show that a statistical correction for a known distance-related artifact in tractography results in large changes in connectivity patterns. Our results suggest that care should be taken in using tractography to assess …
Doug Ruthven And Jorg Karger: Their Individual And Collective Contributions To The Field Of Zeolite Science And Engineering, Dhananjai B. Shah
Doug Ruthven And Jorg Karger: Their Individual And Collective Contributions To The Field Of Zeolite Science And Engineering, Dhananjai B. Shah
Chemical & Biomedical Engineering Faculty Publications
Prof. Doug Ruthven and Prof. Jörg Kärger are two giants in the field of zeolite science and engineering. Over their academic careers encompassing almost forty years each, they have contributed significantly to the advancement of fundamental understanding of adsorption and diffusion in zeolites as well as their industrial applications. The author, in the beginning of his academic career, had an opportunity to spend two years as a post-doctoral fellow in Prof. Ruthven’s laboratory at the University of New Brunswick (1975–1977). This experience actually motivated me to spend my academic career in working in the field of zeolite adsorption and …
Anwendung Von Interferenz- Und Ir-Mikroskopie Zur Charakterisierung Und Untersuchung Des Stofftransportes In Nanoporösen Materialien, Lars Heinke, Christian Chmelik, Pavel Kortunov, Sergey Vasenkov, Douglas M. Ruthven, Dhananjai B. Shah, Jörg Kärger
Anwendung Von Interferenz- Und Ir-Mikroskopie Zur Charakterisierung Und Untersuchung Des Stofftransportes In Nanoporösen Materialien, Lars Heinke, Christian Chmelik, Pavel Kortunov, Sergey Vasenkov, Douglas M. Ruthven, Dhananjai B. Shah, Jörg Kärger
Chemical & Biomedical Engineering Faculty Publications
Die Anwendung der Interferenz-Mikroskopie bedeutet einen entscheidenden Durchbruch in der Untersuchung des Stofftransports von Gastmolekülen in nanoporösen Wirtsmaterialien. Diese Technik ermöglicht die Beobachtung der zeitaufgelösten intrakristallinen Konzentrationsprofile, die durch eine Änderung des umgebenden Gasdruckes entstehen. Dieser Ansatz wurde zur Untersuchung von Adsorptions- und Desorptionsprozessen in verschiedenen Zeolithsystemen verwendet. Die Vorteile dieser Technik, vor allem wenn sie mit Infrarotabsorptionsmessungen kombiniert wird, werden an Hand der experimentellen Resultate des Methanol-in-Ferrierit-Systems illustriert.