Engineering Commons^™

Pharmaceutical Scheduling Using Simulated Annealing And Steepest Descent Method, Bryant Jamison Spencer

Graduate Theses, Dissertations, and Problem Reports

In the pharmaceutical manufacturing world, a deadline could be the difference between losing a multimillion-dollar contract or extending it. This, among many other reasons, is why good scheduling methods are vital. This problem report addresses Flexible Flowshop (FF) scheduling using Simulated Annealing (SA) in conjunction with the Steepest Descent heuristic (SD).

FF is a generalized version of the flowshop problem, where each product goes through S number of stages, where each stage has M number of machines. As opposed to a normal flowshop problem, all ‘jobs’ do not have to flow in the same sequence from stage to stage. The …

Towards A Framework For Smart Manufacturing Adoption In Small And Medium-Sized Enterprises, Sameer Mittal

Graduate Theses, Dissertations, and Problem Reports

Smart Manufacturing (SM) paradigm adoption can scale production with demand without compromising on the time for order fulfillment. A smart manufacturing system (SMS) is vertically and horizontally connected, and thus it can minimize the chances of miscommunication. Employees in an SME are aware of the operational requirements and their responsibilities. The machine schedules are prepared based on the tasks a machine must perform. Predictive maintenance reduces the downtime of machines. Design software optimizes the product design. Production feasibility is checked with the help of simulation. The concepts of product life cycle management are considered for waste reduction. Employee safety, and …

Chemometric Calibration Of Surface Enchanced Raman Spectra For Quantitative Analysis, Xiaofei Shi

Graduate Theses, Dissertations, and Problem Reports

Raman spectroscopy, recognized as a powerful analytical technique, has been widely employed in many fields especially in the detection of hazard material containing in food or water. However, multiplexed analyte quantification based on Raman spectra remains a challenge due to the difficulties in accurate and precise modeling of the relationship between multiple analyte concentrations and dense spectral data with noise.

In this work, a statistical procedure was developed to efficiently generate high-quality calibration models quantifying the analyte concentrations versus spectra relationship. The resulting calibration models are able to provide estimated concentration ranges (which reflect both point and uncertainty estimates) for …

Development Of A Task Analysis Tool To Estimate Shoulder Strain During A Lifting Task, Christopher Wayne Moore

Graduate Theses, Dissertations, and Problem Reports

Musculoskeletal disorders of the shoulder have a huge impact on the workplace and employees. Due to the complexity and high mobility of the shoulder, developing a task analysis tool with a focus on the shoulder is difficult, and while there are some ergonomic analysis tools that do consider the shoulder to varying degrees in the analysis, none focus purely on the shoulder. Therefore, this research was undertaken in an attempt to develop a shoulder-based task analysis tool for the shoulder. However, since the scope of work involving the shoulder is so vast, the tool in this research focuses on unobstructed, …

Analysis Of User Preference With N95 And Powered Air-Purifying Respirators In A Healthcare Work Environment, Brittany Renee Carver

Graduate Theses, Dissertations, and Problem Reports

For those working in the healthcare field, personal protective equipment is vital. Healthcare workers are often first responders when it comes to dealing with patients who are infected or when a disease outbreak occurs. The Occupational Safety and Health Administration (OSHA) requires all healthcare operations to provide employee protection against blood borne pathogens. With the increase of life-threatening disease outbreaks, such as SARS in 2003 and Ebola in 2014, it is of the upmost importance to make sure respirators are best suited for users and acceptable for long term use. It has been shown through previous studies that due to …

Analysis Of The Integration Of Dfm Techniques And Effective Machining Parameter Selection In Metal Parts Manufacturing, Omar Ahmed Al-Shebeeb

Graduate Theses, Dissertations, and Problem Reports

This dissertation investigates the minimization of part design with self-locating features. The research focuses primarily on self-fastening characteristics, standardization of parts, and minimal use of fasteners. Further, the present research studies the design for base parts in the construction of a moving joint system, in order to locate potential part and system design improvements. This process may then be extended to industrial applications in the manufacturing industry. Relatively little work to date has examined the significance of Design for Manufacturing Techniques (DFMT), with their inherent machine element systems and machining parameters to investigate which DFMT has the most influence on …

Performance Study Of An Unconventional Breathresponse Papr Against A N95 Ffr And Conventional Paprs, Huihui Yang

Graduate Theses, Dissertations, and Problem Reports

Healthcare workers (HCWs) are the first responders when infectious pathogens occur. Powered air-purifying respirators (PAPRs) are one of the most widely used personal protective equipment for healthcare workers. Currently, few studies have been performed with HCWs in the actual healthcare work environments to assess discomforts, acceptance and protective efficiency towards wearing and use of PAPRs. The main purpose of this dissertation was to introduce and assess a brand new unconventional PAPR (Koken breath-response PAPR). The protection performance and user preferance of this unconventional PAPR were studided and compared to that of a N95 FFR and traditional PAPRs.

Firstly, a laboratory …

Energy Efficiency Evaluation Of Blower Heater Non-Purge Compressed Air Dryers, Alexandra M. Botts

Graduate Theses, Dissertations, and Problem Reports

There are several compressed air dryers available for industrial use including, refrigerant, desiccant, and membrane. This research focuses on twin tower regenerative closed loop desiccant dryers, specifically: blower heater non-purge (BHNP) with and without cooling water pumps, Compressed-air Heater Purge (CHP), Blower Heater Purge (BHP), and Pressure Swing Heaterless (PSH). These styles of dryers are used mainly in industries that require extremely dry air such as, food manufacturing, medical air, or sensitive technology manufacturers. The research was conducted by collecting and analyzing real time current draw data on air compressors and associated dryers at eight different facilities (13 compressor systems) …

Can Fitts' Throughput Be A Predictor Of Muscle Fatigue – A Study Based On Metacarpal Gloves?, Sachin Sah

Graduate Theses, Dissertations, and Problem Reports

In this study, Fitts’ throughput was used to estimate throughput for metacarpal gloves. Fitts’ throughput combines speed and accuracy during target transfer/movement tasks into a single performance index. It was hypothesized that the throughput will be affected by the glove condition and it will exhibit a relationship with the physiological response of hand muscles and perceived exertions. Fifteen healthy participants (10 males, 5 females) were recruited for data collection. Each participant performed a series of target transfer tasks using four glove conditions: (1) a pigskin leather (glove 1); (2) a synthetic fiber glove (glove 2); (3) a goat-grain leather glove …

Effect Of Metacarpal Gloves On Pinch And Grip Strength, Aaron Anthony Fonner

Graduate Theses, Dissertations, and Problem Reports

Hand Injuries are common in industrial settings. In 2014 alone, there were 137,440 total cases of hand injuries in the United States that required days away from work. Hand injuries can be classified into six general categories: lacerations, fractures and dislocations, soft tissue injuries and amputations, infections, burns and high pressure injuries. Some of these injuries can be prevented with proper personal protective equipment. In recent times, metacarpal gloves are widely used to protect the workers against hand/metacarpal injuries in various industries including mining. The benefits of wearing metacarpal gloves for protection are unquestionable, but little is known about how …