Engineering Commons^™

Multiscale Spatio-Temporal Modeling Of Cell Population In Tissue Architecture And Drug Delivery Nanoparticles, Mohammad Aminul Islam

Doctoral Dissertations

"Multiscale nature of a biological system span at many order of magnitudes in time and space. Molecular interaction at lower scale is connected with the higher scale behavior of tissue or organism. Integrating the dynamics and information at different time and space can give a fundamental physiological understanding of the higher level phenomena. But complex features, functions, interconnectivity between different scales and lack of information on the fundamental physiological property make the model difficult and computationally challenging. The multiscale modeling approach can bridge the gap between different scale by a systemic integration of the complex dynamic behavior.

Here, the focus …

A Systems And Cost Analysis Of Human Rated Mars Entry, Descent, And Landing Vehicles, Paul Daniel Friz

Doctoral Dissertations

"Cost is one of the biggest obstacles to sending humans to Mars. However, spacecraft costs are typically not taken into consideration until after the preliminary vehicle and mission concepts have been designed. Once costs have been estimated, managers and project teams often lack confidence that the final cost of the mission will match the preliminary estimates. The present work provides a robust methodology for using cost as a valid metric early in the design phase of future human Mars Entry, Descent, and Landing (EDL) vehicles. This is done in three parts. First, state of the art parametric costing methods are …

Hydrodynamics Of Trickle Bed Reactors (Tbrs) Packed With Industrial Catalyst Using Advanced Measurement Techniques, Mohammed Jaber Al-Ani

Doctoral Dissertations

"The impacts of the packing characteristics on the hydrodynamics od a trickle bed reactor (TBR) have been investigated using advanced measurements techniques of Gamma-ray densitometry (GRD) and Optical fiber probe and conventional measurement techniques of high-frequency differential pressure transducer and load cell. Two different reactor sizes of bench and pilot plant scale were used. Bench-scale TBR carried out the experiments to assess phase distribution and catalyst utilization with 1.18 cm inside diameter and 72 cm length at ambient pressure and temperature. The mixture of catalyst and fine particles displayed considerable improvements in the phase distribution, liquid holdup profile, and catalyst …

Microstructural Evolution Of Zirconium Carbide (Zrcₓ) Ceramics Under Irradiation Conditions, Raul Florez

Doctoral Dissertations

A comprehensive understanding of the microstructural evolution of Zirconium Carbide (ZrC₂) ceramics under irradiation conditions is required for their successful implementation in advanced Gen-IV gas-cooled nuclear reactors. The research presented in this dissertation focusses on elucidating the ion and electron irradiation response of ZrC₂ ceramics. In the first part of the research, the microstructural evolution was characterized for ZrC₂ ceramics irradiated with 10 MeV Au³⁺ ions up to doses of 30 displacement per atom (dpa) at 800 ºC. Coarsening of the defective microstructure, as a function of dose, was revealed by transmission electron microscopy analysis. …

Investigating The Use Of Different Types Of Sealant Materials For Cement Remedial Applications, Murad Mohammedahmed Abdulfarraj

Doctoral Dissertations

"The overall objective is to investigate the ability of several material to mitigate cement failures such as channels, fractures, and micro-annuli in oil and gas wells. The sealant material that can also be used in the wells that are used for geologic storage of carbon dioxide CO₂. Evaluating the sealant material is critical to improve the zonal isolation of the wells, which would lead to safer operations. The approach of this dissertation is to utilize particles gel that has been used successfully in conformance control application, and epoxy resin systems, that have superior seal characteristics compared to conventional …