Engineering Commons^™

Estimating Passive Material Properties And Fiber Orientation In A Myocardial Infarction Through An Optimization Scheme Using Mri And Fe Simulation, Dimitri Mojsejenko

Theses and Dissertations--Mechanical Engineering

Myocardial infarctions induce a maladaptive ventricular remodeling process that independently contributes to heart failure. In order to develop effective treatments, it is necessary to understand the way and extent to which the heart undergoes remodeling over the course of healing. There have been few studies to produce any data on the in-vivo material properties of infarcts, and much less on the properties over the time course of healing. In this paper, the in-vivo passive material properties of an infarcted porcine model were estimated through a combined use of magnetic resonance imaging, catheterization, finite element modeling, and a genetic algorithm optimization …

A Metrics-Based Sustainability Assessment Of Cryogenic Machining Using Modeling And Optimization Of Process Performance, Tao Lu

Theses and Dissertations--Mechanical Engineering

The development of a sustainable manufacturing process requires a comprehensive evaluation method and fundamental understanding of the processes. Coolant application is a critical sustainability concern in the widely used machining process. Cryogenic machining is considered a candidate for sustainable coolant application. However, the lack of comprehensive evaluation methods leaves significant uncertainties about the overall sustainability performance of cryogenic machining. Also, the lack of practical application guidelines based on scientific understanding of the heat transfer mechanism in cryogenic machining limits the process optimization from achieving the most sustainable performance.

In this dissertation, based on a proposed Process Sustainability Index (ProcSI …