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Coronal Fractures Of The Distal Femoral Condyle: A Biomechanical Evaluation Of Four Internal Fixation Constructs, David J. Hak, James Nguyen, Shane Curtiss, Scott Hazelwood
Coronal Fractures Of The Distal Femoral Condyle: A Biomechanical Evaluation Of Four Internal Fixation Constructs, David J. Hak, James Nguyen, Shane Curtiss, Scott Hazelwood
Biomedical Engineering
This study evaluated different fixation methods in posterior femoral condyle coronal fractures. A standardised osteotomy was created in synthetic composite femurs and fixed with one of four methods (one 3.5 mm diameter screw, two 3.5 mm screws, one 6.5 mm screw, two 6.5 mm screws). The stiffness and mean loads to specified displacements were measured. The stiffness of two 6.5 mm screws was significantly greater than both single 3.5 mm screw (3567 versus 2584 N/mm; p = 0.0075) and double 3.5 mm screws (3567 versus 2080 N/mm; p = 0.003). There was no statistical difference in the stiffness of one …
Prevention Of Atrophic Nonunion Development By Recombinant Human Bone Morphogenetic Protein-7, Takeshi Makino, David J. Hak, Scott Hazelwood, Shane Curtiss, A. Hari Reddi
Prevention Of Atrophic Nonunion Development By Recombinant Human Bone Morphogenetic Protein-7, Takeshi Makino, David J. Hak, Scott Hazelwood, Shane Curtiss, A. Hari Reddi
Biomedical Engineering
Severe periosteal and soft tissue disruption at the time of fracture may result in the formation of an atrophic nonunion. We have developed a reproducible atrophic nonunion in an animal model. The purpose of this study was to evaluate whether the immediate application of recombinant human BMP-7 to the fracture site could rescue the healing process in this nonunion model. A total of 56 three month old Fisher 344 rats were utilized. A 1.25mm diameter K-wire was inserted into the femur in a retrograde fashion, and a mid-diaphyseal closed transverse fracture was created using a standard three point bending device. …