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Engineering Commons™

Open Access. Powered by Scholars. Published by Universities.®

2005

Biomedical Engineering and Bioengineering

Cleveland State University

Articles 1 - 3 of 3

Full-Text Articles in Engineering

Blood Flow Measurements With Magnetic Resonance Phase Velocity Mapping, George P. Chatzimavroudis Apr 2005

Blood Flow Measurements With Magnetic Resonance Phase Velocity Mapping, George P. Chatzimavroudis

Chemical & Biomedical Engineering Faculty Publications

Magnetic resonance (MR) phase velocity mapping (PVM) is a non-invasive technique that can measure the flow velocity in any spatial direction in an imaging slice. This technique has wide application in the clinical field in quantifying blood flow, as well as in non-biomedical areas. This review describes the value and/or potential of MR PVM as a diagnostic/monitoring technique in heart valve regurgitation and in the total cavo-pulmonary connection. A single slice placed in the aortic root can accurately quantify the aortic regurgitant volume. A multi-slice control volume method has high potential for the quantification of the mitral regurgitant volume. …

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Segmentation Of Non-Viable Myocardium In Delayed Enhancement Magnetic Resonance Images, Arunark Kolipaka, George P. Chatzimavroudis, Richard D. White, Thomas P. O’Donnell, Randolph M. Setser Apr 2005

Segmentation Of Non-Viable Myocardium In Delayed Enhancement Magnetic Resonance Images, Arunark Kolipaka, George P. Chatzimavroudis, Richard D. White, Thomas P. O’Donnell, Randolph M. Setser

Chemical & Biomedical Engineering Faculty Publications

Purpose: To evaluate six algorithms for segmenting non-viable left ventricular (LV) myocardium in delayed enhancement (DE) magnetic resonance imaging (MRI). Methods: Twenty-three patients with known chronic ischemic heart disease underwent DE-MRI. DE images were first manually thresholded using an interactive region-filling tool to isolate non-viable myocardium. Then, six thresholding algorithms, based on the image intensity characteristics of either LV blood pool (BP), viable LV myocardium, or both, were applied to each image. For the Mean−2SDBP algorithm, thresholds were equal to the mean BP intensity minus twice its standard deviation. For the Mean+2SDSemi, Mean+3SDSemi, Mean+2SDAuto …

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Relationship Between The Extent Of Non-Viable Myocardium And Regional Left Ventricular Function In Chronic Ischemic Heart Disease, Arunark Kolipaka, George P. Chatzimavroudis, Richard D. White, Michael L. Lieber, Randolph M. Setser Jan 2005

Relationship Between The Extent Of Non-Viable Myocardium And Regional Left Ventricular Function In Chronic Ischemic Heart Disease, Arunark Kolipaka, George P. Chatzimavroudis, Richard D. White, Michael L. Lieber, Randolph M. Setser

Chemical & Biomedical Engineering Faculty Publications

Purpose. To define the relationship between left ventricular (LV) regional contractile function and the extent of myocardial scar in patients with chronic ischemic heart disease and multi-vessel coronary artery disease. Methods. Twenty-three patients with chronic ischemic heart disease and 5 healthy volunteers underwent magnetic resonance imaging (MRI). In patients, the relative area ( Percent Scar) and transmural extent (Transmurality) of myocardial infarction were computed from short-axis delayed enhancement images. In each image, myocardial segments were categorized based on the extent of infarction they contained, with 6 categories each for Percent Scar and Transmurality: normal, from healthy volunteers; and 0%; 1–25%, …

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