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Full-Text Articles in Engineering
Quartz-Mems: Wet Chemical Etching Assisted By Electromagnetic Energy Sources For The Development Of Quartz Crystal To Be Used For Microelectromechanical Systems, William J. Clower
Quartz-Mems: Wet Chemical Etching Assisted By Electromagnetic Energy Sources For The Development Of Quartz Crystal To Be Used For Microelectromechanical Systems, William J. Clower
Doctoral Dissertations
Quartz crystal resonators have been the most commonly used timing devices to date. Today's timing market requires devices to be as small as possible and consume smaller amounts of energy. Because of the market demand, many startup companies have formed to develop silicon resonators as timing devices. Silicon resonators have poor noise and temperature performance (due to its linear temperature versus frequency coefficient). At the moment the only advantage that silicon resonators have over quartz crystal resonators is a small form factor. The photolithography processing method currently being used in industry is a very tedious task, requiring multiple etching steps …
Thermoelectric Elisa For Quantification Of 8ohdg In A Microfluidic Device, Gergana Nestorova
Thermoelectric Elisa For Quantification Of 8ohdg In A Microfluidic Device, Gergana Nestorova
Doctoral Dissertations
This research demonstrates the feasibility of a novel method for performing thermoelectric enzyme-linked immunosorbent assay (ELISA) in a microfluidic device. The feasibility of the thermoelectric ELISA is demonstrated by measuring the concentration of 8-hydroxy 2-deoxyguanosine (8OHdG) in urine samples from amyloid precursor protein (APP) transgenic mice. The detection method is based on formation of a complex between 8OHdG and anti-8OHdG capture antibody conjugated to biotin. The complex is immobilized over the measuring junctions of a thermopile via biotin streptavidin interaction. The concentration of the analyte is determined by using enzyme linked secondary IgG antibody specific to the primary one. The …
Multiscale Modeling Study Of Methanol Oxidation By Ion-Modified Mdh Enzymes, Purnima Kharidehal
Multiscale Modeling Study Of Methanol Oxidation By Ion-Modified Mdh Enzymes, Purnima Kharidehal
Doctoral Dissertations
Enzymes have been considered as molecular electrocatalysts due to their extraordinary characteristics such as their ability to accelerate reactions enormously, to operate under physiological conditions, and to produce fewer by-products during a catalytic reaction. However, enzyme based fuel cells have been reported to have power output and stability limitations, which are restricting the use of this kind of fuel cell to small electronic devices. Methanol dehydrogenase (MDH) is one such enzyme, which oxidizes methanol and other primary alcohols to their corresponding aldehydes. The active site of MDH contains a divalent cation (Ca2+), a co-factor pyrrolo-quinoline quinone (PQQ), several amino acids, …