Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Engineering
Co-Assembly Behavior Of Neutral And Zwitterionic Amphiphilic Block Copolymers In The Fabrication Of Glassy Polymer Vesicles, Elina Ghimire
Co-Assembly Behavior Of Neutral And Zwitterionic Amphiphilic Block Copolymers In The Fabrication Of Glassy Polymer Vesicles, Elina Ghimire
Honors Theses
Polymersomes, also known as polymer vesicles, are hollow capsules fabricated through the solution assembly of amphiphilic block copolymers. Polymer vesicles have garnered a great deal of interest in materials science because of their potential application in areas such as drug delivery, diagnostics and imaging, gene therapy, and as nanoreactors. The goal of this project is to understand the factors that affect the arrangement of triblocks in vesicle membrane via the study of the co-assembly behavior of linear amphiphilic triblocks with different hydrophilic blocks. We investigated the self- and co-assembly behavior of amphiphilic triblock copolymers with neutral hydrophilic blocks. Moreover, we …
Investigating The Effect Of Hydrophilic Block Length On The Co-Assembly Behavior Of Amphiphilic Triblock Copolymers, Alexandra M. Garrett
Investigating The Effect Of Hydrophilic Block Length On The Co-Assembly Behavior Of Amphiphilic Triblock Copolymers, Alexandra M. Garrett
Honors Theses
Polymer vesicles and micelles have been of interest in the scientific community for the past few decades due to potential biomedical applications in areas such as drug delivery, nanoreactors, and biosensing. Polymer vesicles and micelles are formed through the self-assembly of amphiphilic block copolymers. The objective of this project is to gain a better understanding of the influence of hydrophilic block copolymer length and composition in controlling the resulting morphologies from the co-assembly of triblock copolymers. First, a hydrophobic block composed of poly(methyl acrylate) was synthesized using reversible addition-fragmentation chain-transfer (RAFT) polymerization mediated by a difunctional chain-transfer agent. The block …