Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Publication
Articles 1 - 2 of 2
Full-Text Articles in Engineering
Thiol–Ene Photopolymerization: A Simple Route To Pro-Antimicrobial Networks Via Degradable Acetals (Pandas), William Martin
Thiol–Ene Photopolymerization: A Simple Route To Pro-Antimicrobial Networks Via Degradable Acetals (Pandas), William Martin
Honors Theses
The World Health Organization (WHO) has brought the growing epidemic of antibiotic resistance bacteria to the attention of the public and has expressed the need for the development of new methods of defense. In this direction, bioactive aldehyde essential oils have been shown to effectively act as antibiotic and antifungal agents. These bioactive compounds, when used in their pure form, are volatile and lack environmental stability. In this thesis, we describe the synthesis of pro-antimicrobial networks via degradable acetals (PANDAs) using thiol-ene photopolymerization. PANDAs were used as a new model for the high loading and release of bioactive aldehyde-containing compounds …
Antimicrobial Materials Via Thiol-Ene Chemistry, Dahlia Amato
Antimicrobial Materials Via Thiol-Ene Chemistry, Dahlia Amato
Dissertations
With the increasing prevalence of antimicrobial resistance, the escalation of opportunistic/pathogenic infections is a looming global crisis. To avoid the pitfalls of conventional antibiotics, this dissertation focuses on developing macromolecular solutions to develop novel antimicrobial materials based on essential oils (thymol, carvacrol, and aldehydes). It is well established that essential oil derivatives exhibit high potency towards a wide range of pathogenic microbes. The rapid photopolymerization kinetics, limited by-products, and homogeneous network formation afforded by thiol-ene photopolymerization are utilized to either encapsulate essential oil derivatives or convert them into monomers which can subsequently be incorporated into new antimicrobial materials with new …