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Selected Works

Debbie Chachra

Articles 1 - 19 of 19

Full-Text Articles in Engineering

An Interactive Exploration Of Gender And Engineering: Unpacking The Experience, Debbie Chachra, Lynn Stein, Alisha Sarang-Sieminski, Caitrin Lynch, Yevgeniya Zastavker Oct 2012

An Interactive Exploration Of Gender And Engineering: Unpacking The Experience, Debbie Chachra, Lynn Stein, Alisha Sarang-Sieminski, Caitrin Lynch, Yevgeniya Zastavker

Debbie Chachra

The engineering student experience is understood to differ for male and female students; gendered interactions affect the development of academic and professional role confidence, as well as engineering identity. The purpose of this session is twofold. First, we aim to introduce participants to concepts of gender schemas, privilege, and identity using a range of interactive activities, including brainstorming and structured discussion. Second, we intend to share information about and obtain feedback on a Gender Discussion Exploration Kit, which the participants will be encouraged to review, use, and share at their home institutions.


Effect Of Applied Uniaxial Stress On Rate And Mechanical Effects Of Cross-Linking In Tissue-Derived Biomaterials, Debbie Chachra, Paul Gratzer, Christopher Pereira, J. Lee Jul 2012

Effect Of Applied Uniaxial Stress On Rate And Mechanical Effects Of Cross-Linking In Tissue-Derived Biomaterials, Debbie Chachra, Paul Gratzer, Christopher Pereira, J. Lee

Debbie Chachra

Conformational changes in collagen fibrils, and indeed the triple helix, can be produced by application of mechanical stress or strain. We have demonstrated that the rate of cross-linking in glutaraldehyde and epoxide homobifunctional reagents can be modulated by uniaxial stress (strain). Two poly(glycidyl ether) epoxides were used: Denacol® EX-810 (a small bifunctional reagent), and Denacol EX-512 (a large polyfunctional reagent). To prevent any possible effect from being masked by saturation of cross-linking sites, bovine pericardium was cross-linked to such an extent that the increase in collagen denaturation temperature, Td, was one-half of the maximal rise achievable with …


Outside The Classroom: Gender Differences In Extracurricular Activities Of Engineering Students, Debbie Chachra, Helen Chen, Deborah Kilgore, Sheri Sheppard Jul 2012

Outside The Classroom: Gender Differences In Extracurricular Activities Of Engineering Students, Debbie Chachra, Helen Chen, Deborah Kilgore, Sheri Sheppard

Debbie Chachra

Data from the Academic Pathways Study, a component of the NSF-funded Center for the Advancement of Engineering Education, were used to investigate engineering student involvement in extracurricular activities. The study design used a variety of methods: the results presented here are from longitudinal and cross-sectional surveys of engineering students as well as interviews with graduating seniors. Quantitative data from both surveys suggest that women place higher importance on extracurricular activities than their male counterparts, as well as reporting higher participation in both engineering-related and non-engineering-related extracurricular activities. In addition, the importance of non-engineering extracurricular activities and the level of involvement …


Work In Progress - Using Video And Self-Reflection To Enhance Undergraduate Teams, Nick Tatar, Debbie Chachra, Yevgeniya Zastavker, Jonathan Stolk Jul 2012

Work In Progress - Using Video And Self-Reflection To Enhance Undergraduate Teams, Nick Tatar, Debbie Chachra, Yevgeniya Zastavker, Jonathan Stolk

Debbie Chachra

Engineers today must be able to communicate and collaborate in teams. They also must be comfortable making adjustments within the team to maintain flow and progress toward project goals. With these goals in mind, students in a first-semester engineering seminar course were asked to videotape a team meeting in their design course and to write a self-reflection paper after viewing their video. After analyzing the video, students were asked to provide clear suggestions in their self-reflection paper for improving their own and their team's performance. Our preliminary analysis showed that video-supported reflections: 1) may be more effective than memory for …


Shelf-Life Of Bioprosthetic Heart Valves: A Structural And Mechanical Study, Maryse Julien, Dany Letouneau, Yves Marois, Alain Cardou, Martin King, Robert Guidoin, Debbie Chachra, J. Lee Jul 2012

Shelf-Life Of Bioprosthetic Heart Valves: A Structural And Mechanical Study, Maryse Julien, Dany Letouneau, Yves Marois, Alain Cardou, Martin King, Robert Guidoin, Debbie Chachra, J. Lee

Debbie Chachra

This study was undertaken to evaluate the influence of storage conditions on the shelf-life of porcine bioprosthetic valves. Fifty-five unimplanted porcine bioprostheses have been evaluated. The valves were stored in 0.5% buffered glutaraldehyde solution for different periods of time (7, 23 and 32 months). Twenty-eight valves were refrigerated while the remaining valves were stored at room temperature. The pH of the glutaraldehyde solution at room temperature decreased with time of storage, while that kept in the refrigerator remained stable over the course of the study. Macroscopic observations showed that the valve tissues kept at room temperature, especially for the periods …


Drowning In Method, Thirsty For Values: A Call For Cultural Inquiry, Jonathan Stolk, Mark Somerville, Debbie Chachra Jul 2012

Drowning In Method, Thirsty For Values: A Call For Cultural Inquiry, Jonathan Stolk, Mark Somerville, Debbie Chachra

Debbie Chachra

A decade or more has passed since publication of most calls for reform in engineering education. In the ensuing time, there has been significant work on the design, implementation, and transferability of appropriate methodsand techniques - accompanied by, in most cases, little discussion of the values and beliefs of the people involved. But many theories of change rely on a fundamental shift in human beliefs and values, and purport that institutionalization of methods is impossible without this shift. Given this, now may be a reasonable time to re-visit the questions: What are the values of people involved in engineering education, …


Beyond Course-Based Engineering Ethics Instruction Commentary On “Topics And Cases For Online Education In Engineering”, Debbie Chachra Jul 2012

Beyond Course-Based Engineering Ethics Instruction Commentary On “Topics And Cases For Online Education In Engineering”, Debbie Chachra

Debbie Chachra

Discusses how online forums and materials could be used to enhance face-to-face courses in engineering and science ethics.


Lumbar Vertebral Density And Mechanical Properties In Aged Ovariectomized Rats Treated With Estrogen And Norethindrone Or Norgestimate, Carla Vanin, Neil Maclusky, Debbie Chachra, Mehran Kasra, Marc Grynpas, Robert Casper Jul 2012

Lumbar Vertebral Density And Mechanical Properties In Aged Ovariectomized Rats Treated With Estrogen And Norethindrone Or Norgestimate, Carla Vanin, Neil Maclusky, Debbie Chachra, Mehran Kasra, Marc Grynpas, Robert Casper

Debbie Chachra

OBJECTIVE: This study was designed to investigate the effects of estrogen alone or combined with two different progestins, norethindrone or norgestimate, on bone density and compressive mechanical properties in an aged rat model.

STUDY DESIGN: Twenty 11-month-old female Sprague-Dawley rats were sham operated (intact control) and 80 wee overiectomized. Three groups of 20 ovariectomized rats were implanted with Silastic silicon rubber (Dow Corning, Midland, Mich.) capsules containing 5% estradiol (wt/wt) in cholesterol. All rats in the intact control (group 1) and the ovariectomized (group 2) and the first of the overiectomized plus estrogen (group 3) groups were injected subcutaneously daily …


Fluoride Treatment Increased Serum Igf-1, Bone Turnover, And Bone Mass, But Not Bone Strength, In Rabbits, C. Turner, L. Garetto, A. Dunipace, W. Zhang, M. Wilson, Marc Grynpas, Debbie Chachra, R. Mcclintock, M. Peacock, G. Stookey Jul 2012

Fluoride Treatment Increased Serum Igf-1, Bone Turnover, And Bone Mass, But Not Bone Strength, In Rabbits, C. Turner, L. Garetto, A. Dunipace, W. Zhang, M. Wilson, Marc Grynpas, Debbie Chachra, R. Mcclintock, M. Peacock, G. Stookey

Debbie Chachra

We hypothesized that fluoride partly acts by changing the levels of circulating calcium-regulating hormones and skeletal growth factors. The effects of oral fluoride on 24 female, Dutch-Belted, young adult rabbits were studied. The rabbits were divided into two study groups, one control and the other receiving about 16 mg fluoride/rabbit/day in their drinking water. After 6 months of fluoride dosing, all rabbits were euthanized and bone and blood samples were taken for analyses. Fluoride treatment increased serum and bone fluoride levels by over an order of magnitude (P < 0.001), but did not affect body weight or the following serum biochemical variables: urea, creatinine, phosphorus, total protein, albumin, bilirubin, SGOT, or total alkaline phosphatase. No skeletal fluorosis or osteomalacia was observed histologically, nor did fluoride affect serum PTH or Vitamin D metabolites (P > 0.4). BAP was increased 37% (P < 0.05) by fluoride; serum TRAP was increased 42% (P < 0.05); serum IGF-1 was increased 40% (P < 0.05). Fluoride increased the vertebral BV/TV by 35% (P …


Work In Progress - A Provisional Competency Assessment System, Mark Somerville, Debbie Chachra, Jonathan Chambers, Ellen Cooney, Kristen Dorsey, John Geddes, Gill Pratt, Kathryn Rivard, Ann Schaffner, Lynn Stein, Jonathan Stolk, Stephen Westwood, Yevgeniya Zastavker Jul 2012

Work In Progress - A Provisional Competency Assessment System, Mark Somerville, Debbie Chachra, Jonathan Chambers, Ellen Cooney, Kristen Dorsey, John Geddes, Gill Pratt, Kathryn Rivard, Ann Schaffner, Lynn Stein, Jonathan Stolk, Stephen Westwood, Yevgeniya Zastavker

Debbie Chachra

Over the last two years Olin College has been defining and implementing a provisional system to develop and assess student competency levels. The system particularly emphasizes the importance of creating a community of practice that includes not only faculty but also staff and students. In this paper we provide an overview of the design process, and comment on the results of our first year of implementing the system.


The Effect Of Different Hormone Replacement Therapy Regimens On The Mechanical Properties Of Rat Vertebrae, Debbie Chachra, M. Kasra, Carla Vanin, N. Maclusky, R. Casper, Marc Grynpas Jul 2012

The Effect Of Different Hormone Replacement Therapy Regimens On The Mechanical Properties Of Rat Vertebrae, Debbie Chachra, M. Kasra, Carla Vanin, N. Maclusky, R. Casper, Marc Grynpas

Debbie Chachra

The purpose of this study was to examine the effects of estrogen replacement, in concert with three different progestin regimens, on the mechanical properties of rat lumbar vertebrae. Ninety-two Sprague-Dawley rats (11 months old) were divided into six groups for treatment. The first group was an intact control, the second group (OVX) was ovariectomized only, and the third group (estrogen-only) was ovariectomized and received continuous estrogen through a 17-estradiol implant. The remaining groups were ovariectomized and received estrogen and progestin (norethindrone, NET) therapy; 3 g of NET was injected daily (estrogen plus continuous NET), or 6 g of NET was …


The Effect Of Fluoride Treatment On Bone Mineral In Rabbits, Debbie Chachra, C. Turner, A. Dunipace, Marc Grynpas Jul 2012

The Effect Of Fluoride Treatment On Bone Mineral In Rabbits, Debbie Chachra, C. Turner, A. Dunipace, Marc Grynpas

Debbie Chachra

Fluoride therapy has been used clinically for many years, but its use remains controversial and many basic questions remain unanswered. Accordingly, this study returns to an animal model to study the effects of high doses of fluoride on bone mineral in rabbits. Twelve rabbits, aged 3½ months at the start of the study, received drinking water fluoridated at 100 ppm while their 12 control counterparts drank distilled water. All rabbits were sacrificed after 6 months. Fluoride was readily incorporated into femoral cortical bone (7473 ± 966 ppm F versus 1228 ± 57 ppm in controls; P < 0.00005). Fluoride therapy led …


Differential Effects Of Ovariectomy On The Mechanical Properties Of Cortical And Cancellous Bone In Rat Femora And Vertebrae, Debbie Chachra, J.M. Lee, M. Kasra, Marc Grynpas Mar 2012

Differential Effects Of Ovariectomy On The Mechanical Properties Of Cortical And Cancellous Bone In Rat Femora And Vertebrae, Debbie Chachra, J.M. Lee, M. Kasra, Marc Grynpas

Debbie Chachra

The purpose of this study was to evaluate the effects of ovariectomy on the mechanical properties of bone in the aged Sprague-Dawley rat model of osteoporosis. Eight female rats were sacrificed at the start of the study, at the age of four months. Twenty-four remaining rats were then bilaterally ovariectomized (OVX), and another twenty-four served as controls. Eight rats from each group were sacrificed at five, ten or fifteen weeks. The mean density of L1 vertebral bodies from OVX rats was lower than in their control counterparts, as was the compressive modulus, the ultimate compressive stress and the toughness. The …


Bone Quality In Animal Models Of Osteoporosis, Marc Grynpas, Debbie Chachra, Kathleen Lundon Mar 2012

Bone Quality In Animal Models Of Osteoporosis, Marc Grynpas, Debbie Chachra, Kathleen Lundon

Debbie Chachra

The use of animal models is a very powerful tool for the preclinical assessment of potential therapies for osteoporosis. However, the effective use of animal models has two prerequisites. The first is the use of appropriate techniques to assess the overall effects of therapy on bone. As spontaneous fractures do not occur in any species other than humans, the efficacy of a therapy cannot be assessed by its impact on fracture incidence. Instead, a suite of parameters (collectively referred to as ‘bone quality’), including bone architecture, mineralization and mechanical properties, is examined. While techniques such as histomorphometry and dual-energy x-ray …


Fluoride And Mineralized Tissues, Debbie Chachra, Anya Vieira, Marc Grynpas Feb 2012

Fluoride And Mineralized Tissues, Debbie Chachra, Anya Vieira, Marc Grynpas

Debbie Chachra

This review focuses on the interaction of fluoride with the material properties of bone and teeth, which is of clinical, scientific, and public health interest. These tissues are composed primarily of collagen (protein) and hydroxyapatite (mineral), and their mechanical function depends on the properties of the constituents, their proportions, the interface, and the three-dimensional structure. Changing any of these may have clinical consequences. Fluoride interacts with mineralized tissues in a number of ways. At low doses, the fluoride may be passively incorporated into the mineral, stabilizing it against dissolution; this is one of the mechanisms by which municipally fluoridated water …


A New Tool To Assess The Mechanical Properties Of Bone Due To Collagen Degradation, C. Wynnyckyj, S. Omelon, K. Savage, M. Damani, Debbie Chachra, Marc Grynpas Feb 2012

A New Tool To Assess The Mechanical Properties Of Bone Due To Collagen Degradation, C. Wynnyckyj, S. Omelon, K. Savage, M. Damani, Debbie Chachra, Marc Grynpas

Debbie Chachra

Current clinical tools for evaluating fracture risk focus only on the mineral phase of bone. However, changes in the collagen matrix may affect bone mechanical properties, increasing fracture risk while remaining undetected by conventional screening methods such as dual energy x-ray absorptiometry (DXA) and quantitative ultrasound (QUS). The mechanical response tissue analyzer (MRTA) is a non-invasive, radiation-free potential clinical tool for evaluating fracture risk. The objectives of this study were two-fold: to investigate the ability of the MRTA to detect changes in mechanical properties of bone as a result of treatment with 1 M potassium hydroxide (KOH) and to evaluate …


From Pollen To Polyester, Debbie Chachra Nov 2011

From Pollen To Polyester, Debbie Chachra

Debbie Chachra

Polyester bees are all over the Northeast. The interesting thing about them is that they dig underground tunnels, about the width of your pinky finger, where they lay their eggs. To protect their larvae from heat, cold, fungus, bacteria and other dangers, the bees line these chambers with a clear, cellophanelike substance. The larvae then live underground for most of their lives in these reinforced cells.


Outcomes Of A Longitudinal Administration Of The Persistence In Engineering Survey, Ozgur Eris, Debbie Chachra, Helen Chen, Sheri Sheppard, Larry Ludlow, Camelia Rosca, Tori Bailey, George Toye Oct 2011

Outcomes Of A Longitudinal Administration Of The Persistence In Engineering Survey, Ozgur Eris, Debbie Chachra, Helen Chen, Sheri Sheppard, Larry Ludlow, Camelia Rosca, Tori Bailey, George Toye

Debbie Chachra

BACKGROUND Understanding more about student decisions to leave engineering may leadto higher retention. This study builds on the literature and focuses on theexperiences of a cohort of students who aimed to complete their undergraduatework in 2007. PURPOSE (HYPOTHESIS) This paper presents the outcomes of the longitudinal administration of thePersistence in Engineering survey. The goal was to identify correlates of persistencein undergraduate engineering education and professional engineeringpractice. DESIGN/METHOD The survey was administered seven times over four years to a cohort of studentswho had expressed interest in studying engineering. At the end of thestudy, the participants were categorized as persisters or non-persisters.Repeated …


Persistence, Engagement, And Migration In Engineering Programs, Matthew Ohland, Sheri Sheppard, Gary Lichtenstein, Ozgur Eris, Debbie Chachra, Richard Layton Jun 2011

Persistence, Engagement, And Migration In Engineering Programs, Matthew Ohland, Sheri Sheppard, Gary Lichtenstein, Ozgur Eris, Debbie Chachra, Richard Layton

Debbie Chachra

Records from the Multiple-Institution Database forInvestigating Engineering Longitudinal Development indicatethat engineering students are typical of students in other majorswith respect to: persistence in major; persistence by gender andethnicity; racial/ethnic distribution; and grade distribution. Datafrom the National Survey of Student Engagement show that thissimilarity extends to engagement outcomes including course challenge,faculty interaction, satisfaction with institution, and overallsatisfaction. Engineering differs from other majors most notablyby a dearth of female students and a low rate of migration into themajor. Noting the similarity of students of engineering and othermajors with respect to persistence and engagement, we proposethat engagement is a precursor to persistence. We …