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LSU Master's Theses

Theses/Dissertations

Imaging

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Full-Text Articles in Engineering

Poly (Lactic Co-Glycolic) Acid Nanoparticles: Synthesis Using Millifluidic Chip And Interaction With Red Blood Cells, Sumit Libi Jan 2015

Poly (Lactic Co-Glycolic) Acid Nanoparticles: Synthesis Using Millifluidic Chip And Interaction With Red Blood Cells, Sumit Libi

LSU Master's Theses

Nanoparticles (NPs) have recently been developed for application as drug carriers in different fields, including biomedical engineering. This study was focused on the use of a millifluidic chip for synthesis of polymeric poly (lactic co-glycolic acid) (PLGA) NPs and the understanding of PLGA NPs interaction and effect on red blood cells (RBCs). A method for NPs synthesis on a millifluidic chip was developed, exploiting the precise flow control offered by this device. PLGA NPs ranging from 230nm to 350nm in diameter were produced. Smaller NPs of lower polydispersity were synthesized at higher flow rates of the aqueous phase; increase in …


Assessment Of Shearing Phenomenon And Porosity Of Porous Media Using Microfocus Computed Tomography, Bashar Adeeb Alramahi Jan 2004

Assessment Of Shearing Phenomenon And Porosity Of Porous Media Using Microfocus Computed Tomography, Bashar Adeeb Alramahi

LSU Master's Theses

Microfocus x-ray computed tomography (μCT) is a powerful non-destructive scanning technique to study the internal fabric of granular materials. In this thesis, μCT was applied to two cases. The first case involves studying the behavior of particles in a triaxial specimen during shearing. Three-dimensional translation and rotation of the particles were tracked throughout the shearing process, and they were used to calculate the local strain distributions. Moreover, the local dilatancy angle distribution was calculated throughout experiment. These distributions were compared to study the changes in the behavior of the particles at different stages of the test. It was noticed that …