Engineering Commons^™

Emerging Technologies And Advanced Analyses For Non-Invasive Near-Surface Site Characterization, Aser Abbas

All Graduate Theses and Dissertations, Fall 2023 to Present

This dissertation introduces novel techniques for estimating the soil small-strain shear modulus (G_max) and damping ratio (D), crucial for modeling soil behavior in various geotechnical engineering problems. For G_max estimation, a machine learning approach is proposed, capable of generating two-dimensional (2D) images of the subsurface shear wave velocity, which is directly related to G_max. The dissertation also presents a method for estimating frequency dependent attenuation coefficients from ambient vibrations collected using 2D arrays of seismic sensors deployed across the ground surface. These attenuation coefficients can then be used in an inversion process …

Microfabrication Of Silicon Carbide And Metallized Polymers Using A Femtosecond Laser, Joseph Taylor Eddy

Theses and Dissertations

Femtosecond lasers deliver a high peak concentration of optical power while maintaining low average power. With an accompanying optical setup, this power can be focused and used for high-precision fabrication of metallized polymers via ablation, creating conductive structures on a thin film. These lasers can also be harnessed in tandem with hydrofluoric acid and the two-photon absorption principle to selectively etch silicon carbide, a very durable and machining-resistant semiconductor with desirable properties. This thesis presents improvements made to the Laser-Assisted Chemical Etching (LACE) technique and the ablation system. ��, the two- photon absorption coefficient of silicon carbide, is measured and …

Investigating Applications Of Deep Learning For Diagnosis Of Post Traumatic Elbow Disease, Hugh James

McKelvey School of Engineering Theses & Dissertations

Traumatic events such as dislocation, breaks, and arthritis of musculoskeletal joints can cause the development of post-traumatic joint contracture (PTJC). Clinically, noninvasive techniques such as Magnetic Resonance Imaging (MRI) scans are used to analyze the disease. Such procedures require a patient to sit sedentary for long periods of time and can be expensive as well. Additionally, years of practice and experience are required for clinicians to accurately recognize the diseased anterior capsule region and make an accurate diagnosis. Manual tracing of the anterior capsule is done to help with diagnosis but is subjective and timely. As a result, there is …

Design Of An Offner-Chrisp Imaging Spectrometer For A Planetary Fluorescence Instrument, Tristan Wells Carlson

McKelvey School of Engineering Theses & Dissertations

Spectrometers have been an integral part of space exploration in the late 20th and 21st centuries and will continue to provide quantitative measurements to answer exciting questions like, “Is or was there life on other planets?” PERISCOPE, Probe for Exploring Regolith and Ice by Subsurface Classification of Organics, Polycyclic aromatic hydrocarbons, and Elements, is a next generation spectrometer designed to explore icy worlds like Europa. It uses time-resolved ultraviolet (UV) fluorescence spectroscopy, a technique that identifies organic molecules, polycyclic aromatic hydrocarbons (PAH), and rare earth elements (REE). Photon wavelength discrimination is very important for this technique and is accomplished by …

Investigations Of External Resources And The Impact Of Imaging On Patient Flow In The Emergency Department, Marisa Shehan

All Theses

The problems associated with Emergency Department (ED) crowding are numerous, varied, and complex. Though overcrowded Emergency Departments are frequently attributed to overcrowded hospitals, crowding is also impacted by bottlenecks in patient flow. While discrete-event simulation (DES) is commonly used to model ED flow, external resources are typically excluded from these models due to their complexity and the limited amount of known information for these processes. Instead, external resources such as consults, labs, and imaging are modeled using estimation and/or educated guesswork. In this study, the impact of imaging on patient flow was assessed through data analysis of specific imaging factors, …

Three Dimensional Photonics Structures: Design And Applications, Mansoor Sultan

Theses and Dissertations--Electrical and Computer Engineering

Photonics is an emerging technology for light control, emission, and detection. Photonic devices control photons the same way electronic circuits control electrons in active or passive mode depending on the energy requirement of the device. This dissertation will discuss the design, fabrication, testing of photonic structures with applications including imaging and renewable energy. First, we developed a novel lithography method for fluoropolymer resist based on variable pressure electron beam lithography (VP-EBL). VP-EBL proves to be an efficient method for patterning a widely used, but challenging to process, fluoropolymer, Teflon AF. However, rather than solely mitigating charging, the ambient gas is …

Injectable Ct/Mri Contrast Agent For Gastrointestinal Tumor Tracking, Luna Zhang

McKelvey School of Engineering Theses & Dissertations

Gastrointestinal cancers remain to be of the most common and deadly cancers worldwide. Early detection and treatments are crucial for reducing mortality and improving patient outcome. Radiation therapy is a non-invasive localized tumor treatment method, and utilizes radiation to kill the cancerous cells and shrink tumors at specific sites. Precise localization at the target tumor site is therefore important before radiation therapy, especially for gastrointestinal tumor sites located in the moving bowel. Currently, invasive endoscopies along with ink tattoos are used for identifying tumor location, which often require sedation and bring much discomfort. Imaging tests, including CT and MRI, play …

Quantifying Blood Flow Patterns In The Pediatric Heart Using Blood Speckle Imaging, Harrison Dean

Biomedical Engineering Undergraduate Honors Theses

Congenital Heart Disease (CHD) is the most common type of congenital disease worldwide. Echocardiography using Doppler ultrasound is typically used to diagnose and monitor CHD; however, it is angle-dependent in nature and as a result is limited in its ability to accurately evaluate ventricular function. Blood Speckle Imaging (BSI) is a novel, angle-independent imaging modality that provides detailed blood flow information and visualization within a given area using speckle-tracking. In this study, velocity-field information obtained from BSI was used to calculate flow parameters such as kinetic energy (KE) and circulation using a custom created MATLAB program. BSI was performed on …

Design Of Multi-Layered Lenses For Resolusion Enhancement, S. M. Zia Uddin

Theses and Dissertations

Lenses are important optical device having numerous applications in our day-to-day life. As the conventional lenses, we use concave or convex lenses. These lenses are made with natural materials and the image quality imperfect. Furthermore, they are bulky, and design is complex. Consequently, mass production is difficult.

The shapes of entrance and exit faces of lenses has impact on its imaging capability. The Lens material also play a vital role for reconstructing the image. Flat lenses can be considered as a good alternative of the conventional lenses. One of the advantages of this Flat lenses is that it can restore …

Saturation Behaviors In Deep Turbulence, Jeffrey R. R. Beck

Dissertations, Master's Theses and Master's Reports

Distributed-volume atmospheric turbulence near the ground significantly limits the performance of incoherent imaging and coherent beam projection systems operating over long horizontal paths. Defense, military and civilian surveillance, border security, and target identification systems are interested in terrestrial imaging and beam projection over very long horizontal paths, but atmospheric turbulence can blur the imagery and aberrate the laser beam such that they are beyond usefulness. While many post-processing and adaptive optics techniques have been developed to mitigate the effects of turbulence, many of these techniques do not work as expected in stronger volumetric turbulence, or in many cases don't work …

Development And Characterization Of An Iot Network For Agricultural Imaging Applications, Jacob D. Wahl

Master's Theses

Smart agriculture is an increasingly popular field in which the technology of wireless sensor networks (WSN) has played a large role. Significant research has been done at Cal Poly and elsewhere to develop a computer vision (CV) and machine learning (ML) pipeline to monitor crops and accurately predict crop yield numbers. By autonomously providing farmers with this data, both time and money are saved. During the past development of a prediction pipeline, the primary focuses were CV and ML processing while a lack of attention was given to the collection of quality image data. This lack of focus in previous …

Flash Lab: A High-Speed Imaging Laboratory, Cody D. Hatch

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

To help students become better acquainted with high-speed instrumentation and measurement techniques, a high-speed imaging laboratory for the College of Engineering is equipped with a high-speed camera and schlieren imaging device. The laboratory will be used for labs in classes, such as Instrumentation, Thermal/Fluids Lab, Experimental Solids, and Mechanical Experiments. In addition, graduate students will use it for research purposes. The laboratory also has the potential to have a course associated with it that would include the image processing techniques for a variety of applications (e.g., a course on high-speed imaging). The scope of this project will be to create …

Wireless Sensor Network Optimization For Radio Tomographic Imaging, Grant T. Nafziger

Theses and Dissertations

Radio tomographic imaging (RTI) is a form of device-free, passive localization (DFPL) that uses a wireless sensor network (WSN) typically made up of affordable, low-power transceivers. The intent for RTI is to have the ability to monitor a given area, localizing and tracking obstructions within. The specific advantages rendered by RTI include the ability to provide imaging, localization, and tracking where other well developed methods like optical surveillance fall short. RTI can function through optical obstructions such as smoke and even physical obstructions like walls. This provides a tool that is particularly valuable for tactical operations like emergency response and …

Development Of High-Speed Photoacoustic Imaging Technology And Its Applications In Biomedical Research, Yun He

McKelvey School of Engineering Theses & Dissertations

Photoacoustic (PA) tomography (PAT) is a novel imaging modality that combines the fine lateral resolution from optical imaging and the deep penetration from ultrasonic imaging, and provides rich optical-absorption–based images. PAT has been widely used in extracting structural and functional information from both ex vivo tissue samples to in vivo animals and humans with different length scales by imaging various endogenous and exogenous contrasts at the ultraviolet to infrared spectrum. For example, hemoglobin in red blood cells is of particular interest in PAT since it is one of the dominant absorbers in tissue at the visible wavelength.The main focus of …

In Vivo Metabolic And Vascular Response To Hypoxia In Twist Knockdown Murine Breast Cancer, Brandon Sturgill

Graduate Theses and Dissertations

Twist transcription factor is often overexpressed in aggressive tumors. Although needed in early embryonic development for organogenesis, Twist is known to induce an epithelial to mesenchymal transition in cells. In cancer, epithelial to mesenchymal transitions can lead to increased motility and invasiveness. It has also been linked to metabolic reprogramming and increased metastatic risk. Furthermore, metabolic preferences can increase proliferation, enhance metastatic potential, and influence the site of metastasis. We hypothesize that Twist directly affects the metabolism of cancer cells. We expect to see in vivo what we have seen in vitro; Twist overexpression should promote a shift away from …

Modeling And Validation Of Tissue Optical Properties In The Photon Transport Regime, Katelyn Heath

Biomedical Engineering Undergraduate Honors Theses

Early detection of changes in epithelial cells, such as the development of neoplastic formations seen in epithelial dysplasia, can indicate regions of the epithelial tissue that are at a high risk for cancerous formation. Using concepts from diffuse reflectance spectroscopy, a Monte Carlo model was developed to predict the reflectance measured by a detector at a small source-detector separation on a microendoscope. The Monte Carlo results were then used to calculate a mathematical relationship between the reflectance and distance that can be used to determine optical properties in a tissue sample. This model was validated with liquid phantoms of specified …

Vector Flow Imaging In Pediatric Cardiology - Extracting And Validating Data, Mason Belue

Biomedical Engineering Undergraduate Honors Theses

In the field of bedside cardiac diagnostic imaging, Doppler Ultrasound (DU) is the gold standard for diagnosing heart conditions. The largest benefit of DU is its ability to noninvasively image cardiac flow and allow the estimation of blood velocity and quantification of anatomical disease. However, to get correct velocity estimation, the position of the transducer in relation to the flow field needs to be known. This is the problem of angle/direction dependency and limits DUs accuracy when imaging in areas where perfect alignment or exact position of the transducer in relation to flow field is not possible or known, such …

Counterfeit Detection With Multispectral Imaging, Ian Spatz

Electrical Engineering Undergraduate Honors Theses

Multispectral imaging is becoming more practical for a variety of applications due to its ability to provide hyper specific information through a non-destructive analysis. Multispectral imaging cameras can detect light reflectance from different spectral bands of visible and nonvisible wavelengths. Based on the different amount of band reflectance, information can be deduced on the subject. Counterfeit detection applications of multispectral imaging will be decomposed and analyzed in this thesis. Relations between light reflectance and objects’ features will be addressed. The process of the analysis will be broken down to show how this information can be used to provide more insight …

Enhancing The Resolution Of Imaging Systems By Spatial Spectrum Manipulation, Wyatt Adams

Dissertations, Master's Theses and Master's Reports

Much research effort has been spent in the 21st century on superresolution imaging techniques, methods which can beat the diffraction limit. Subwavelength composite structures called ``metamaterials" had initially shown great promise in superresolution imaging applications in the early 2000s, owing to their potential for nearly arbitrary capabilities in controlling light. However, for optical frequencies they are often plagued by absorption and scattering losses which can decay or destroy their interesting properties. Similar issues limit the application of other superresolution devices operating as effective media, or metal films that can transfer waves with large momentum by supporting surface plasmon polaritons. In …

Optical Vortex And Poincaré Analysis For Biophysical Dynamics, Anindya Majumdar

Dissertations, Master's Theses and Master's Reports

Coherent light - such as that from a laser - on interaction with biological tissues, undergoes scattering. This scattered light undergoes interference and the resultant field has randomly added phases and amplitudes. This random interference pattern is known as speckles, and has been the subject of multiple applications, including imaging techniques. These speckle fields inherently contain optical vortices, or phase singularities. These are locations where the intensity (or amplitude) of the interference pattern is zero, and the phase is undefined.

In the research presented in this dissertation, dynamic speckle patterns were obtained through computer simulations as well as laboratory setups …

Microwave Detection Of Surface Breaking Cracks In Metallic Structures Under Heavy Corrosion And Paint, John Robert Gallion

Masters Theses

"We live in the world of "aging infrastructures". In this environment, critical and heavily utilized infrastructure, i.e. ships, planes, bridges, etc., are operating at or beyond their designed age. Replacement is no longer an option and "retirement for cause" is the current approach to maintenance and replacement. Consequently, there is an ever-increasing demand for efficient and robust nondestructive evaluation (NDE) methods that can determine the physical health of these structures. Large structures, which are primarily made of metals, either steel or aluminum, are susceptible to high-stress cracking and corrosion. Stress-induced cracks in heavily corroded steel, used in bridges, railroads, storage …

Fluorescence Guided Tumor Imaging: Foundations For Translational Applications, Jessica P. Miller

McKelvey School of Engineering Theses & Dissertations

Optical imaging for medical applications is a growing field, and it has the potential to improve medical outcomes through its increased sensitivity and specificity, lower cost, and small instrumentation footprint as compared to other imaging modalities. The method holds great promise, ranging from direct clinical use as a diagnostic or therapeutic tool, to pre-clinical applications for increased understanding of pathology. Additionally, optical imaging uses non-ionizing radiation which is safe for patients, so it can be used for repeated imaging procedures to monitor therapy, guide treatment, and provide real-time feedback. The versatile features of fluorescence-based optical imaging make it suited for …

Radio Tomographic Imaging Using A Modified Maximum Likelihood Estimator For Image Reconstruction In Various Environments, Antwon R. Gallagher

Theses and Dissertations

Radio Tomographic Imaging (RTI) is an emerging Device-Free Passive Localization (DFPL) technology. Radio Tomographic Imaging (RTI) involves using a set of small low cost wireless transceivers to create a Wireless Sensor Network (WSN) around an Area of Interest (AoI). Furthermore, the Received Signal Strength (RSS) between transceiver pairs is utilized to reconstruct an image from the signal attenuation caused by an object disrupting the links. This image can then be utilized for multiple applications ranging from localization to target detection and tracking. This enhances the importance of image resolution in order to capture the actual size of the objects as …

Development Of Low Frequency Electron Paramagnetic Resonance Methods And Instrumentation For Biological Applications, Laura A. Buchanan

Electronic Theses and Dissertations

EPR is a powerful biophysical tool that can be used to measure tumor physiology. With the addition of magnetic field gradients, the spectral properties of paramagnetic species can be mapped. To facilitate EPR imaging, methods and instrumentation at frequencies between 250 MHz and 1 GHz were developed.

At low spin concentrations, the rapid scan background signal is often many times larger than the EPR signal of interest. To help remove the background contribution, a data acquisition procedure that takes advantage of a cross-loop resonator and bipolar power supplies was developed at 250 MHz. In this procedure, two scans are collected. …

Experimental And Model-Based Terahertz Imaging And Spectroscopy For Mice, Human, And Phantom Breast Cancer Tissues, Tyler Bowman

Graduate Theses and Dissertations

The goal of this work is to investigate terahertz technology for assessing the surgical margins of breast tumors through electromagnetic modeling and terahertz experiments. The measurements were conducted using a pulsed terahertz system that provides time and frequency domain signals. Three types of breast tissues were investigated in this work. The first was formalin-fixed, paraffin-embedded tissues from human infiltrating ductal and lobular carcinomas. The second was human tumors excised within 24-hours of lumpectomy or mastectomy surgeries. The third was xenograft and transgenic mice breast cancer tumors grown in a controlled laboratory environment to achieve more data for statistical analysis.

Experimental …

Optical Mapping Of Cardiac Electromechanics, Hanyu Zhang

All ETDs from UAB

Sudden cardiac arrest is a leading cause of death in the world. One of the common causes of sudden cardiac arrest is acute regional ischemia due to coronary occlusion. However, the mechanism of arrhythmia onset in this setting is still unclear. Previous stud-ies suggest that abnormal mechanical stretch during acute regional ischemia may play a role in initiating arrhythmia through triggering ectopic electrical activation. Optical map-ping has been widely used in cardiac electrophysiological research in the past decades. Compared with conventional electrical mapping techniques, optical mapping offers a number of advantages. But a major limitation of optical mapping is that …

Leveraging 3d Models For Sar-Based Navigation In Gps-Denied Environments, Zachary A. Reid

Browse all Theses and Dissertations

This thesis considers the use of synthetic aperture radar (SAR) to provide absolute platform position information in scenarios where GPS signals may be degraded, jammed, or spoofed. Two algorithms are presented, and both leverage known 3D ground structure in an area of interest, e.g. provided by LIDAR data, to provide georeferenced position information to airborne SAR platforms. The first approach is based on the wide-aperture layover properties of elevated reflectors, while the second approach is based on correlating backprojected imagery with digital elevation imagery. Both of these approaches constitute the system we have designated: SARNAV. Building on 3D backprojection, localization …

Development Of A Capacitive Photocurrent Scanning Microscope With Carrier Depletion Super-Resolution., Austin Levi Carver

Electronic Theses and Dissertations

This dissertation discusses the development and refinement of a new two-dimensional imaging technique, funded in part through a NSF MRI equipment development grant. Capacitive-Photocurrent (CPC) spectroscopy allows for the probing of samples without the requirement of free-carrier collection. The CPC technique allows for the studying of various states within a material. With this electronic measurement technique, we developed a scanning technique, scanning-CPC, that provides two-dimensional material property images without requiring environments that must be high-vacuum, humidity-controlled, or temperature-controlled. This new technique also provides two-dimensional, electronic mapping without damaging samples. With this successful result, we then modified an existing resolution improving …

Impact Of Near-Field-To-Far-Field Transformation On Sar Images Formed In An Indoor Non-Anechoic Environment, Jacob D. Compaleo

Browse all Theses and Dissertations

This work investigates the impact of the near-field-to-far-field transformation (NFFFT) algorithm on phase history measurement collections completed in the Sensors and Signals Exploitation Laboratory (SSEL). SSEL is an indoor non-anechoic environ- ment that is at risk to some measurement interferences such as multiple bounces. Complete 360-degree phase history measurements of scale model aircraft are con- ducted at varying range values within the near-field limit. These measurements are calibrated with the Mie series scattering solution for a sphere. After calibration, the measurements are transformed using the NFFFT, with radar cross-section (RCS) estimated. RCS of the transformed data is compared with the …

Novel Pet Systems And Image Reconstruction With Actively Controlled Geometry, Ke Li

McKelvey School of Engineering Theses & Dissertations

Positron Emission Tomography (PET) provides in vivo measurement of imaging ligands that are labeled with positron emitting radionuclide. Since its invention, most PET scanners have been designed to have a group of gamma ray detectors arranged in a ring geometry, accommodating the whole patient body. Virtual Pinhole PET incorporates higher resolution detectors being placed close to the Region-of-Interest (ROI) within the imaging Field-of-View (FOV) of the whole-body scanner, providing better image resolution and contrast recover. To further adapt this technology to a wider range of diseases, we proposed a second generation of virtual pinhole PET using actively controlled high resolution …