Engineering Commons^™

Molecular Mechanisms Of Oxidative Stress On Molecular Motors, Addison Caspari-Linhardt

Honors Theses

Astronauts encounter many forms of ionizing radiation during space travel. Ionizing radiation has been seen to cause cancer, cataracts, radiation sickness, tissue damage, hereditary effects, and damage to the central nervous system. Ionizing radiation can damage DNA molecules through oxidation, as well as other vital proteins like molecular motors. Kinesin-1 is a molecular motor protein that essential to intracellular transport. Microtubules serve as the “roadway” for kinesin transport, where kinesin converts chemical energy from ATP hydrolysis into mechanochemical “steps” to move along the microtubules. Optical trapping has been used in previous research to measure single kinesin motor properties. We have …

Effects Of Static Mixer Geometry On Polyurethane Properties, Christian R. Dixon

Honors Theses

The field of additive manufacturing has gained significant academic interest in the past few decades with a recently developed type of three-dimensional (3D) printing. Reactive extrusion additive manufacturing combines precursor materials within a static mixer (SM) head, where polymerization begins before deposition. Variable static mixer geometries currently exist, but the relationship between mixer geometry and post-polymerization mechanical properties is undefined. To elucidate this relationship, a series of experiments with identical chemistry was performed using a high shear SM, a low shear SM, and a comparative batch reaction. While higher shear mixing trends with faster polymerization for step-growth polymerizations, consistent precursor …

Utilizing The Oxygen-Barrier Properties Of Poly(Isobutylene) To Enhance Photon Upconversion In Thermoplastic Elastomers, Haley Carroll

Honors Theses

Upconversion (UC) is the conversion of low energy light to higher energy light. It is utilized for a broad range of applications such as solar energy harvesting, microscopy of cellular biology, and cancer therapy. Specifically, triplet-triplet annihilation UC (TTA-UC) involves two dye species, a sensitizer and an annihilator, which are capable of upconverting noncoherent light such as sunlight. Traditionally, TTA-UC is achieved in solution, rubbers, or glasses, however, this work probes the capabilities of a thermoplastic elastomer (TPE) matrix to examine the effect of phase-separated morphology on the energy transfers necessary for TTA-UC. The system herein consists of poly(styrene-isobutylene-styrene) (SIBstar) …

An Open-Baffle Motional Feedback Loudspeaker, Matthew Quinlivan, William Harvie

Honors Theses

A dynamic loudspeaker mounted in an open baffle has the same parameters as a loudspeaker in free space. A subwoofer mounted in an open baffle has a small total quality factor and therefore the frequency above which the driver has a significant output is too high despite the subwoofer's low resonant frequency. To address this issue, we implemented a motional feedback circuit with the goal of introducing both velocity feedback and acceleration feedback into the loudspeaker system and thus altering the resonant frequency and total quality factor of the system. After verifying the efficacy of our feedback circuit with computer …

Creation Of A Wooden Model Toy Car As A Learning Module For Students Enrolled In Manufacturing 152, Patrick Brown

Honors Theses

This project involved the design and manufacture of a children’s wooden model toy car constructed on the CME factory floor. Apart from building a children’s toy, the purpose of this project was to introduce younger CME students to a high-quality product made efficiently in regards to manufacture time and total cost. The design for the car required the inclusion of principles from different manufacturing philosophies taught in the CME such as LEAN Manufacturing, which works to eliminate waste from a process, and Design for Manufacture and Assembly, which seeks to reduce cost and cycle time for a product. Through the …

Design And Analysis Of A Process To Convert Methanol Into Dimethyl Ether, Elisa M. White

Honors Theses

A recent economic downturn led to the loss of a contract for a company that sells methanol. The company has two options to recover some of the profit lost from the contract termination. One option is to sell the excess methanol at the spot market price, and the second option is to implement a process to convert the excess methanol into dimethyl ether. This project investigated the implementation of a process to convert the methanol from the lost contract into dimethyl ether. The process was simulated in AVEVA Process Simulation to estimate the size of equipment needed. A toller provided …

Analysis On Fuel Options For Scramjet Engines With The Study To Lower The Starting Mach Number, Sumantra Luitel, Gagan Dangi

Honors Theses

The main objectives of this report were to perform analysis of an ideal scramjet engine, to assess the influence of fuel on endurance factor, and the possibility of lowering the starting Mach Number of the scramjet. In the first part, an ideal cycle parametric analysis was conducted on three different fuels i.e. Liquid Hydrogen (LH2), Jet Propellant 7 (JP-7), and Rocket Propellant (RP-1), taking into account their availability, physical properties, current uses, and potential uses. The detailed analysis is done largely relying on a 9 step Parametric Cycle Analysis technique to study how fuel properties influence the variation of seven …

Evaluating The Effects Of Seismic Loading On Concrete Reinforced Versus Precast Concrete Slab Floor Systems, Mahima Maharjan

Honors Theses

This thesis is part of the senior design capstone project of Ole Miss Department of Civil Engineering. The seismic loadings for the commercial buildings project located in Oxford, Mississippi are evaluated to fulfill the honor thesis requirement. This thesis follows the codes from American Concrete Institute (ACI), International Building Code (IBC), and ASCE-7/SEI (Minimum Design Loads and Associated Criteria for Buildings and Other Structures/Structural Engineering Institute) to design the gravitational loadings and seismic loadings.

Furthermore, a reinforced concrete slab flooring system is replaced with a precast slab flooring system to analyze the most seismic performance effective floor system for the …

Wearables And Wearable Data In Tele-Health Applications, Jack Mazza

Honors Theses

With the sudden emergence of Covid-19, Tele-Health has been forced into the forefront of healthcare. With no human contact, regular in-person doctor or clinic visits could not be made. Unfortunately, there is a gap in patient data for healthcare professionals when making diagnoses remotely. Fortunately, many users are constantly collecting some primary health data through wearables that have become commonplace in users' homes. Tapping into this unused data could provide healthcare professionals with a better picture of patients' health remotely. In this thesis, I will determine whether this wearable data can be a viable addition to Tele-Health applications, providing additional …

Apiary Wagon Frame, Katelyn Franklin, Ryoma Thomas

Honors Theses

The objective of this thesis to demonstrate how our senior capstone project team took a product from a concept to a mass production manufacturing operation, using the knowledge and experience gained through our four years in the Haley Barbour Center for Manufacturing Excellence (CME). Our product, the Apiary Wagon Frame, is an opportunity to reduce the barrier to entry into the hobbyist beekeeping community. In the design process for the Apiary Wagon Frame, we tested several prototypes and different fabrication methods, ending with a product capable of holding twenty hive frames. After building our final prototype, the group created a …

Analyzing The Effects Of E-Hook Peptides On Kinesin-1, Ashton Ward Murrah, Baylee Hope Howard

Honors Theses

Cancer is the second leading cause of death in the United States. Cancerous growth is a result of oncogenes, or mutated genes that increase the rate of cell division in an uncontrolled manner. Cell division, which consists of mitosis and cytokinesis phases, is dependent upon the active movement of kinesin motor proteins along microtubules to rearrange the cytoskeleton for equitable distribution of genetic material to daughter cells. As kinesins are vital to this process, if we could prevent kinesin from binding to the microtubules, cell division would cease.

The goal of this study is to develop a method to prevent …

Improving The Efficacy Of Epinephrine Delivery For Anaphylaxis Through Development Of A Novel Auto-Injector Device And Increased User Education, Jennifer Ansley Myers

Honors Theses

Anaphylaxis is a life-threatening condition caused by the body’s overreaction to a certain allergen. The most widely accepted treatment for this condition is immediate administration of epinephrine, a hormone secreted by the adrenal glands that initiates the body’s fight or flight response, through an intramuscular injection. In most cases, patients that experience anaphylaxis are prescribed an epinephrine auto-injector to carry with them at all times which contains a single dose of epinephrine. Though these devices have been widely accepted for many years, there are many problems caused by their design and the lack of training that their users receive. The …

Design And Production Of A Bathtub Caddy, John Marquez

Honors Theses

The purpose of this thesis is to document and discuss the design and manufacturing process used to produce a bathtub caddy on a large-scale production process for the Center for Manufacturing Excellence Senior Capstone Project. This project was carried out over the Fall of 2020 and Spring 2021 semesters by a team consisting of an Undergraduate Chemical Engineering Undergraduate, two Mechanical Engineering Undergraduate, a Finance Undergraduate, and an Accounting Undergraduate. The objective of this project was to design the product and then a manufacturing process that could be used to at first produce a prototype before planning a ramp up …

Aveva Competition 2021: Dimethyl Ether Production Process, Nicholas Gaouette

Honors Theses

The following study was conducted to assess the economic and process feasibility of a dimethyl ether (DME) production process. A portion of the methanol produced by an existing facility would be used to produce DME through a dehydration reaction. DME production is being considered as a means to compensate for lost methanol revenue, as methanol prices have recently decreased and an excess supply is present on the open market.

The first milestone in the study was the construction of a working process model within AVEVA Process Simulation. This steady-state process model would provide information essential to further design and optimization …

Process Design And Optimization Of A Once-Through Dimethyl Ether Process Using Aveva Process Simulation, Jerrod Scott

Honors Theses

The primary purpose of the project on which I wrote this thesis was to design an optimize a once-through dimethyl ether process utilizing a software called AVEVA Process Simulation. The process was initially modeled and optimized to minimize the EAOC of the distillation column. The result of that effort was an optimized column with six stages with the feed entering the column at stage six. It had a height of 3 m, diameter of 0.44 m, and an EAOC of $65,100. This optimized solution was submitted to a Toller. The Toller provided available equipment to model the plant. From here, …

Introduction Of New Value Stream Through Vermicomposting Process, James Spalding, Joseph Harris

Honors Theses

The purpose of our project is to analyze whether a waste byproduct can be monetized into a viable profit stream for Wonderbird Spirits. Spent grain, a waste byproduct created by the distillation process, is currently the company’s biggest source of material waste. The CME project team designed and built a trommel to aid liquid-solid separation of the spent grain so that the solid portion can be repurposed as feedstock for a vermicomposting setup. We also suggest vermicomposting setup for the distillery based on the needs and capabilities of Wonderbird Spirits. We present financial analyses detailing the cost of creating the …

A Study Of Deep Reinforcement Learning In Autonomous Racing Using Deepracer Car, Mukesh Ghimire

Honors Theses

Reinforcement learning is thought to be a promising branch of machine learning that has the potential to help us develop an Artificial General Intelligence (AGI) machine. Among the machine learning algorithms, primarily, supervised, semi supervised, unsupervised and reinforcement learning, reinforcement learning is different in a sense that it explores the environment without prior knowledge, and determines the optimal action. This study attempts to understand the concept behind reinforcement learning, the mathematics behind it and see it in action by deploying the trained model in Amazon's DeepRacer car. DeepRacer, a 1/18^th scaled autonomous car, is the agent which is trained …

An Investigation Into Cognitive Radio System Performance, Courtney Hardy, Lucas F. Feather, William S. Guy

Honors Theses

The objective of this thesis is to explore cognitive radio performance through an in-depth literature review and an implementation of a software-defined radio prototyping system. Specifically, this thesis investigates the spectrum-sensing aspect of cognitive radio by comparing two spectrum-sensing methods. It was found in the literature review that a system utilizing matched filter detection would provide higher probability of detection in low signal-to-noise ratio environments when compared to a system utilizing energy detection. These spectrum sensing methods were thus implemented and compared in the cognitive radio systems presented in this thesis. Additionally, experiments were conducted to determine the most efficient …

Ethylbenzene Production Case Study And Optimization, Brandon Borek

Honors Theses

The objective of this project was to investigate the process of producing ethylbenzene from the liquid-phase reaction of ethylene and benzene and perform parametric and topological optimizations to increase the net present value of the production facility. To do so, the base case conditions of the process were modeled and quantified economically followed by an investigation into the existing process to determine conditions that could be altered to improve the economic viability of the project. After optimizing the parametric conditions and topology of the process, the net present value of the project was increased by 305 million dollars to 191 …

Design Of An Undergraduate Laboratory Experiment Utilizing A Stirred-Tank, Jacketed Bioreactor, Brennen Middleton

Honors Theses

Bioreactors are utilized in many industries, such as the food, alternative fuel, and pharmaceutical industries, to design and manufacture products. Unlike the similar chemical batch reactors utilized in many chemical processing facilities, bioreactor utilization requires engineers to consider a wider range of operating conditions and parameters. This results in a more complex reaction system and controls network. Due to this, it is imperative for chemical and biomedical engineering students to not only understand the theory surrounding these reactor systems, but also understand how to properly design and perform operating procedures with these systems. Thus, it was determined to create an …

Going Green: A Comparative Analysis Of Green Urbanism In Paris And Shanghai, Jeanne Torp

Honors Theses

As climate change becomes more pressing with each day and as we scramble to slow down the challenges it poses, adapting the means of operation within our cities will become an invaluable tool for reducing humanity’s carbon footprint. This paper seeks to study the ways in which green infrastructure in global cities can be used to do just that—adapting to and mitigating the effects of challenges resulting from climate change. In order to provide a broad overview of the effectiveness of such green infrastructure systems across the globe, this research will focus on two cities that vary greatly in their …

Senior Design Capstone: Using An Engineering Design Process To Create A Sawzall Wobble Fixture For Milwaukee Tools, Tyler Moore

Honors Theses

The overall objective of this design project was to successfully design a fixture to expedite the repairs of Sawzalls at the Milwaukee Tools repairs facility in Greenwood, Mississippi. This project was executed in accordance with guidelines set forth by the Senior Capstone Design class at the University of Mississippi as well as the quality engineers sponsoring the project at Milwaukee Tools. The fixture was created utilizing an engineering design process with the goal of allowing technicians to press two Sawzall wobbles onto an angled Sawzall wobble shaft using an arbor press with just one press. By beginning with a straightforward …

Parametric Design Of Flywheel For An Electric Punch Press, Prashant Dhakal

Honors Theses

Almost all designs start with a design requirement. These may be weight, volume, clearance, and even custom calculations. Finding a solution that meets these requirements often involves tedious and time-consuming iterations. Once the solution has been found, the design must be optimized to find the best possible solution. Finding the ‘best possible design’ requires substantial time and effort dedicated to iterating and analyzing the potential model solutions. This is where Parametric design comes into play. The Parametric design aids in specifying the key parameters of the design and makes changes interactively, with the model updating automatically. The purpose of this …

Design, Analysis, And Optimization Of A Process To Produce Dimethyl Ether From Methanol, Thomas Mathwig

Honors Theses

The company that the engineering team works for is facing a contract loss with one of its customers of methanol. To avoid economic losses, a process has been proposed for converting the unused methanol to dimethyl ether (DME) through a dehydration reaction. After a preliminary simulation of the base case and optimization of the distillation column, an Equivalent Annual Operating Cost (EAOC) of $140,000 was calculated for the column. The EAOC was the sum of the annualized capital investment and the annual operating cost. Determining the process to be worth pursuing, a Toller was brought in to provide rental equipment …

Computational Study On Suppression Of Airfoil Flow Separation Using High-Frequency Translational Surface Actuation, Bibek Gupta

Honors Theses

Flow separation is a phenomenon that occurs when pressure increases in the streamwise direction of a flow, making a distinctive boundary layer or separation bubble. It causes aircraft to experience an increase in drag and noise and a decrease in a lift, hence degrading their aviation performance. This study uses numerical simulations to understand better the effects of high-frequency translational surface actuation (HFTSA) on flow separation control. The numerical simulations mimic the experimental parameters of an experiment performed by Okoye et al. on using the HFTSA system to control flow separation. A symmetrical airfoil structure of chord length of 0.3 …

Analyzing The Lifecycle Of A Modular Cutting Board From Design To Production, Caitlin O'Connor, Achintya Prasad

Honors Theses

This Capstone project is intended to demonstrate the process of product development for a modular cutting board from design to production by applying manufacturing principles, utilizing the stage-gate format, and developing a marketing plan. The guiding principles for the project would be the implementation of lean manufacturing and analyzing the quality, performance, lifecycle cost, and time needed for market introduction. Team voting and assignment occurred in Manufacturing 451 in Fall 2020, and the project was completed during Spring 2021. Teams were required to meet outside of class time in order to discuss ideas and build designs. Lab times were scheduled …

Sizing And Economics Of Solar Powered Indoor Swimming Pool, Aman Bhatta

Honors Theses

With increasing global population and aspiration for higher standards for living, there is a rapid increase in demand for energy. With the concerns of climate change becoming ever more pressing, a shift from the conventional energy source to an alternative green version to meet the energy demand could be of significant interest. A large amount of energy is required to maintain water temperature in the swimming pool at a human comfort temperature. Several studies have been performed to calculate and evaluate the feasibility of powering thermal systems for swimming pools using solar energy. Still, extensive analysis using solar thermal energy …

Hinging, Propping, And Latching Mechanisms For Sunseeker Solar Car, Zachary Ruppenthal

Honors Theses

In this project, designs for the hinging, propping, and latching mechanisms on the 2021 Sunseeker Solar Car were created. These designs allow for the car’s array of solar panels to be held at any desired angle to maximize collection of solar power and give the team access to the battery and driver compartment. Removable telescoping prop rods with pin attachments are used to set the array at a desired angle. The hinging mechanism allows for the array to be lifted vertically prior to rotation in order to avoid interference with the car’s roll cage. To accomplish this, two four-bar linkages …

Versatile Home Workspace Environment, Kayli Holmes

Honors Theses

Since the initial spread of COVID-19, many individuals around the world have experienced a rapid shift from an external workplace, to needing a dedicated workspace within the home. While some individuals have been faced with new distractions like family members and pets, others have been faced with the struggle of having a workspace in common areas, where relaxation and socialization normally occur. Due to the needs for many people to work from home and be isolated from coworkers, it is essential for living spaces to be adaptable to meet these needs. Producing an effective separation can help lead to overall …

Charge Tracing For Determining Electrical Facility Effects On Electric Spacecraft Propulsion Systems., Joseph Backe

Honors Theses

Electric Propulsion Systems are the future of deep space travel. Since its design in 2016 Western Michigan University has been testing a Hall-Thruster from a previous Senior Design Group. One issue with Electric Propulsion Systems is tracing where the electrons go after being used to ionize propellant for spacecraft acceleration. Induced magnetic fields on Earth alter the electron paths found in the vacuum of space.

One solution is the EP TEMPEST. The EP TEMPEST is an electron tracer designed by the Air Force Research Laboratory. The goal of this project is to design an electron tracer like the EP TEMPEST …