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Development Of A Comsol Microdialysis Model, Towards Creation Of Microdialysis On A Chip With Improved Geometries And Recovery, Patrick Pysz
Development Of A Comsol Microdialysis Model, Towards Creation Of Microdialysis On A Chip With Improved Geometries And Recovery, Patrick Pysz
Graduate Theses and Dissertations
Microdialysis (µD) sampling is a diffusion-limited sampling method that has been widely used in different biomedical fields for greater than 35 years. Device calibration for in vivo studies is difficult for current non-steady state analytes of interest correlated with both inflammatory response and microbial signaling molecules (QS); which exist in low ng/mL to pg/mL with molecular weights over a wide range of 170 Da to 70 kDa. The primary performance metric, relative recovery (RR), relating the collected sample to the extracellular space concentration varies from 10% to 60% per analyte even under controlled bench-top conditions. Innovations in microdialysis device design …
Optimization Of Miniaturized Resonant Microwave Cavities For Use In Q-Thrusters, Joshua Steven Pennington
Optimization Of Miniaturized Resonant Microwave Cavities For Use In Q-Thrusters, Joshua Steven Pennington
Graduate Theses and Dissertations
A gedankenexperiment was considered to compare a hypothetical thruster that used no reaction mass to propulsion methods currently in use. A brief discussion of previous research work done on closed resonant cavity thrust devices was conducted. Using the previous work as a template, a simulation plan was devised. Computational models of resonant microwave cavities were constructed and investigated using COMSOL software. These COMSOL simulations were verified against known analytical solutions using Matlab software as a computational tool. Multiphysics simulations were created to study the microwave heating environment of the resonant cavities. From the COMSOL study outputs, the electromagnetic field magnitude, …
A Computational Study Of The Potential For Lng Tanker Polystyrene Foam Insulation Failure Under Fire Exposure, Jeffrey David Martinez
A Computational Study Of The Potential For Lng Tanker Polystyrene Foam Insulation Failure Under Fire Exposure, Jeffrey David Martinez
Graduate Theses and Dissertations
Liquefied natural gas is shipped across the oceans in large marine carriers. The carriers house the LNG using several different insulation systems. One of these systems involves large aluminum spheres insulated with polystyrene foam. Polystyrene foam is very susceptible to heat degradation. This raised issues as to the extent of possible insulation failure caused by a large ship fire. Experiments were done investigating the nature of polystyrene’s thermal degradation, notably by Brauman, Chen, and Matzinger and Butler. A large scale investigation was also performed by Sandia National Laboratory. However, computational modeling of the degradation was lacking. This work set out …