Open Access. Powered by Scholars. Published by Universities.®

Engineering Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 61 - 73 of 73

Full-Text Articles in Engineering

The Role Of Filler-Matrix Interaction On Viscoelastic Response Of Biomimetic Nanocomposite Hydrogels, Alireza Sarvestani, Xuezhong He, Esmaiel Jabbari Jan 2015

The Role Of Filler-Matrix Interaction On Viscoelastic Response Of Biomimetic Nanocomposite Hydrogels, Alireza Sarvestani, Xuezhong He, Esmaiel Jabbari

Esmaiel Jabbari

The effect of a glutamic acid (negatively charged) peptide (Glu6), which mimics the terminal region of the osteonectin glycoprotein of bone on the shear modulus of a synthetic hydorgel/apatite nanocomposite, was investigated. One end of the synthesized peptide was functionalized with an acrylate group (Ac-Glu6) to covalently attach the peptide to the hydrogel phase of the composite matrix. The addition of Ac-Glu6 to hydroxyapatite (HA) nanoparticles (50 nm in size) resulted in significant reinforcement of the shear modulus of the nanocomposite (~100% increase in elastic shear modulus). The reinforcement effect of the Glu6 peptide, a sequence in the terminal region …


Targeted Delivery With Peptidomimetic Conjugated Self-Assembled Nanoparticles, Esmaiel Jabbari Jan 2015

Targeted Delivery With Peptidomimetic Conjugated Self-Assembled Nanoparticles, Esmaiel Jabbari

Esmaiel Jabbari

No abstract provided.


Fabrication And Characterization Of Poly(Propylene Fumarate) Scaffolds With Controlled Pore Structures Using 3-Dimensional Printing And Injection Molding, Kee-Won Lee, Shanfeng Wang, Lichun Lu, Esmaiel Jabbari, Bradford L. Currier, Michael J. Yaszemski Jan 2015

Fabrication And Characterization Of Poly(Propylene Fumarate) Scaffolds With Controlled Pore Structures Using 3-Dimensional Printing And Injection Molding, Kee-Won Lee, Shanfeng Wang, Lichun Lu, Esmaiel Jabbari, Bradford L. Currier, Michael J. Yaszemski

Esmaiel Jabbari

Poly(propylene fumarate) (PPF) is an injectable, biodegradable polymer that has been used for fabricating preformed scaffolds in tissue engineering applications because of in situ crosslinking characteristics. Aiming for understanding the effects of pore structure parameters on bone tissue ingrowth, 3-dimensional (3D) PPF scaffolds with controlled pore architecture have been produced in this study from computer-aided design (CAD) models. We have created original scaffold models with 3 pore sizes (300, 600, and 900 µm) and randomly closed 0%, 10%, 20%, or 30% of total pores from the original models in 3 planes. PPF scaffolds were fabricated by a series steps involving …


Comparison Of Interdiffusion At Polystyrene–Poly(Vinyl Methyl Ether) And Polystyrene–Poly(Isobutyl Vinyl Ether) Interfaces, Esmaiel Jabbari, Nikolaos Peppas Jan 2015

Comparison Of Interdiffusion At Polystyrene–Poly(Vinyl Methyl Ether) And Polystyrene–Poly(Isobutyl Vinyl Ether) Interfaces, Esmaiel Jabbari, Nikolaos Peppas

Esmaiel Jabbari

No abstract provided.


Effect Of Surface Polarity On Wettability And Friction Coefficient Of Silicone Rubber/Poly(Acrylic Acid) Hydrogel Composite, Saeid Kheirandish, Esmaiel Jabbari Jan 2015

Effect Of Surface Polarity On Wettability And Friction Coefficient Of Silicone Rubber/Poly(Acrylic Acid) Hydrogel Composite, Saeid Kheirandish, Esmaiel Jabbari

Esmaiel Jabbari

No abstract provided.


Effects Of Dynamic Fluid Pressure On Chondrocytes Cultured In Biodegradable Poly(Glycolic Acid) Fibrous Scaffolds, Lichun Lu, Xun Zhu, Larry G. Pederson, Esmaiel Jabbari, Bradford Currier, Shawn O'Driscoll, Michael Yaszemski Jan 2015

Effects Of Dynamic Fluid Pressure On Chondrocytes Cultured In Biodegradable Poly(Glycolic Acid) Fibrous Scaffolds, Lichun Lu, Xun Zhu, Larry G. Pederson, Esmaiel Jabbari, Bradford Currier, Shawn O'Driscoll, Michael Yaszemski

Esmaiel Jabbari

No abstract provided.


In Vitro Osteogenic Differentiation Of Marrow Stromal Cells Encapsulated In Biodegradable Hydrogels, Johnna Temenoff, Hansoo Park, Esmaiel Jabbari, Tiffany Sheffield, Richard Lebaron, Catherine Ambrose, Antonios Mikos Jan 2015

In Vitro Osteogenic Differentiation Of Marrow Stromal Cells Encapsulated In Biodegradable Hydrogels, Johnna Temenoff, Hansoo Park, Esmaiel Jabbari, Tiffany Sheffield, Richard Lebaron, Catherine Ambrose, Antonios Mikos

Esmaiel Jabbari

No abstract provided.


Swelling Behavior Of Acrylic Acid Hydrogels Prepared By Γ-Radiation Crosslinking Of Polyacrylic Acid In Aqueous Solution, Esmaiel Jabbari, Samyra Nozari Jan 2015

Swelling Behavior Of Acrylic Acid Hydrogels Prepared By Γ-Radiation Crosslinking Of Polyacrylic Acid In Aqueous Solution, Esmaiel Jabbari, Samyra Nozari

Esmaiel Jabbari

No abstract provided.


Morphology And Structure Of Microcapsules Prepared By Interfacial Polycondensation Of Methylene Bis(Phenyl Isocyanate) With Hexamethylene Diamine, Esmaiel Jabbari Jan 2015

Morphology And Structure Of Microcapsules Prepared By Interfacial Polycondensation Of Methylene Bis(Phenyl Isocyanate) With Hexamethylene Diamine, Esmaiel Jabbari

Esmaiel Jabbari

No abstract provided.


Gelation And Degradation Characteristics Of In Situ Photo-Crosslinked Poly(L-Lactide-Co-Ethylene Oxide-Co-Fumarate) Hydrogels, Alireza Sarvestani, Weijie Xu, Xuezhong He, Esmaiel Jabbari Jan 2015

Gelation And Degradation Characteristics Of In Situ Photo-Crosslinked Poly(L-Lactide-Co-Ethylene Oxide-Co-Fumarate) Hydrogels, Alireza Sarvestani, Weijie Xu, Xuezhong He, Esmaiel Jabbari

Esmaiel Jabbari

No abstract provided.


Effect Of Cd44 Binding Peptide Conjugated To An Engineered Inert Matrix On Maintenance Of Breast Cancer Stem Cells And Tumorsphere Formation, Xiaoming Yang, Samaneh Kamali Sarvestani, Seyedsina Moeinzadeh, Xuezhong He, Esmaiel Jabbari Jan 2015

Effect Of Cd44 Binding Peptide Conjugated To An Engineered Inert Matrix On Maintenance Of Breast Cancer Stem Cells And Tumorsphere Formation, Xiaoming Yang, Samaneh Kamali Sarvestani, Seyedsina Moeinzadeh, Xuezhong He, Esmaiel Jabbari

Esmaiel Jabbari

As cancer cells are affected by many factors in their microenvironment, a major challenge is to isolate the effect of a specific factor on cancer stem cells (CSCs) while keeping other factors unchanged. We have developed a synthetic inert 3D polyethylene glycol diacrylate (PEGDA) gel culture system as a unique tool to study the effect of microenvironmental factors on CSCs response. We have reported that CSCs formed in the inert PEGDA gel by encapsulation of breast cancer cells maintain their stemness within a certain range of gel stiffness. The objective was to investigate the effect of CD44 binding peptide (CD44BP) …


Nanostructure Formation And Transition From Surface To Bulk Degradation In Polyethylene Glycol Gels Chain-Extended With Short Hydroxy Acid Segments, Seyedsina Moeinzadeh, Danial Barati, Samaneh Kamali Sarvestani, Ozan Karaman, Esmaiel Jabbari Jan 2015

Nanostructure Formation And Transition From Surface To Bulk Degradation In Polyethylene Glycol Gels Chain-Extended With Short Hydroxy Acid Segments, Seyedsina Moeinzadeh, Danial Barati, Samaneh Kamali Sarvestani, Ozan Karaman, Esmaiel Jabbari

Esmaiel Jabbari

No abstract provided.


Development Of Biodegradable Poly(Propylene Fumarate)/Poly(Lactic-Co-Glycolic Acid) Blend Microspheres. Ii. Controlled Drug Release And Microsphere Degradation, Diederik Kempen, Lichun Lu, Xun Zhu, Choll Kim, Esmaiel Jabbari, Wouter Dhert, Bradford Currier, Michael Yaszemski Jan 2015

Development Of Biodegradable Poly(Propylene Fumarate)/Poly(Lactic-Co-Glycolic Acid) Blend Microspheres. Ii. Controlled Drug Release And Microsphere Degradation, Diederik Kempen, Lichun Lu, Xun Zhu, Choll Kim, Esmaiel Jabbari, Wouter Dhert, Bradford Currier, Michael Yaszemski

Esmaiel Jabbari

No abstract provided.