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Full-Text Articles in Engineering

Modeling Of Transport In Anatomic Respiratory Airways: Applications In Targeted Drug Delivery And Airborne Pathogenic Transmissions, Mohammad Mehedi Hasan Akash Jan 2023

Modeling Of Transport In Anatomic Respiratory Airways: Applications In Targeted Drug Delivery And Airborne Pathogenic Transmissions, Mohammad Mehedi Hasan Akash

Electronic Theses and Dissertations

This thesis aims to explore the potential of improving the efficacy of drugs for treatment of viral infections by targeting the nasopharynx, which is commonly the first site of infection for many viral pathogens. Currently, intranasal sprays are used, but the standard protocol (“Current Use” or CU) results in suboptimal drug deposition at the nasopharynx. To address this issue, an “Improved Use” or, IU protocol has been proposed, which involves pointing the spray bottle at a shallower angle and aiming slightly towards the cheeks. The IU delivery is also robust to perturbations in spray direction, which highlights the practical utility …


Rational Design Of Advanced Functional Materials For Electrochemical Devices, Shun Lu Jan 2021

Rational Design Of Advanced Functional Materials For Electrochemical Devices, Shun Lu

Electronic Theses and Dissertations

In recent years, there has been a fast-growing trend in developing urea (CO(NH2)2) as a substitute H2 carrier in energy conversion due to its high energy density, nontoxicity, stability, and nonflammability. Urea, a byproduct in the metabolism of proteins and a frequent contaminant in wastewater, is an abundant compound that has demonstrated favorable characteristics as a hydrogen-rich fuel source with 6.7 wt % gravimetric hydrogen content. Also, there is 2-2.5 wt % urea from mammal urine; therefore, 0.5 million ton of additional fuels will be produced per year just from human urine (240 million ton each year). Electrochemical oxidation has …


Bio-Inspired Materials For Electrochemical Sensors, Matthew Joseph Hummel Jan 2021

Bio-Inspired Materials For Electrochemical Sensors, Matthew Joseph Hummel

Electronic Theses and Dissertations

Electrochemical biosensors are a rapidly growing research area that has greatly improved its specificity, accuracy, and precision in the detection of biomolecules in contemporary literature and industry alike. Typically, these systems exist in a three-electrode conformation with a working electrode functioning as the anode, a counter electrode functioning as the cathode, and a reference electrode allowing for the control of potential in the system. The method by which these sensors work is through the sharing of electrons via redox reactions with the target molecule and the working electrode or modifications on its surface. By exploiting the function of biomaterials that …


Development Of Cellulose Acetate-Based Scaffold For Bone Tissue Engineering Applications, Ruhit Sinha Jan 2020

Development Of Cellulose Acetate-Based Scaffold For Bone Tissue Engineering Applications, Ruhit Sinha

Electronic Theses and Dissertations

Cellulose Acetate (CA) based biomaterials are being used as substrates for bone ingrowth applications due to their nontoxic and nonirritant nature coupled with optimum morphology and stiffness. Electrospinning with additives and/or post-treatment has emerged as a viable protocol to further improve mechanical properties of CA and expand its utility. Herein, we highlight the role of potassium chloride (KCl) in association with airdrying to enhance the elastic modulus and tensile strengths of CA fibers. Salt aggregation in between fibers is observed through Scanning Electron Microscopy (SEM), however, Fourier-transform infrared (FTIR) analysis signifies the interactions between K+ ions and acetyl groups. The …


A Series-Elastic Robot For Back-Pain Rehabilitation, Elhussein Shata Jan 2020

A Series-Elastic Robot For Back-Pain Rehabilitation, Elhussein Shata

Electronic Theses and Dissertations

Robotics research has been broadly expanding into various fields during the past decades. It is widely spread and best known for solving many technical necessities in different fields. With the rise of the industrial revolution, it upgraded many factories to use industrial robots to prevent the human operator from dangerous and hazardous tasks. The rapid development of application fields and their complexity have inspired researchers in the robotics community to find innovative solutions to meet the new desired requirements of the field. Currently, the creation of new needs outside the traditional industrial robots are demanding robots to attend to the …


A Seed Dormancy Gene-Mediated Biotechnology To Mitigate Transgene Flow Into Weedy Rice, Luai Nahar Muhammad Jan 2019

A Seed Dormancy Gene-Mediated Biotechnology To Mitigate Transgene Flow Into Weedy Rice, Luai Nahar Muhammad

Electronic Theses and Dissertations

Transgene flows into wild/weedy relatives may cause ecological and economic problems. Seed dormancy is an adaptive trait that distributes germination over time and promotes persistence of weeds in agroecosystems. Silencing natural genes controlling seed dormancy (SD) could promote germination and reduce weed adaptability. The goal of this project was to develop a transgenic mitigation (TM) technology by linking to a primary transgene with an SD gene-silencing structure, as a tandem construct for transformation, to reduce the risk of gene flow into weed populations. In this research, the Bar (Bialaphos) gene for resistance to the glufosinate herbicide was used as a …


Modeling Runoff From Small Agricultural Watersheds In Eastern South Dakota, Bryce Siverling Jan 2019

Modeling Runoff From Small Agricultural Watersheds In Eastern South Dakota, Bryce Siverling

Electronic Theses and Dissertations

The capability to be able to consistently and accurately model any problem has potential time and money savings. The present study aimed to determine if the Natural Resources Conservation Service’s Curve Number (CN) model or the more detailed Soil and Water Assessment Tool (SWAT) Model can consistently and accurately model runoff events from small agricultural fields in Eastern South Dakota. The overall goal was to better understand models used to predict runoff and determine if they can produce accurate estimates of runoff from the watersheds being studied. Runoff measurements were collected from an agricultural field located south of Coleman, South …


Lcd 3d Printing Of A Photocurable Elastomer For Tissue Engineering, Beatriz Luiza De Souza Jan 2018

Lcd 3d Printing Of A Photocurable Elastomer For Tissue Engineering, Beatriz Luiza De Souza

Electronic Theses and Dissertations

Three-dimensional scaffolding is an emerging research area in biomedical and tissue engineering. Scaffolds provide the possibility of growing tissues in a controlled environment, with desired characteristics and properties towards a specific application. A new method to 3D print biodegradable and biocompatible material called Polyglycerol Sebacate Acrylate (PGSA) is demonstrated. PGSA is essentially an acrylated form of PGS using photoinitiator to become a photocurable resin suitable for liquid crystal display (LCD) 3D printing. PGSA was selected because its rheological and crosslinking behavior (and hence its mechanical properties) can be controlled by changes in curing time, temperature, and pressure. This material has …


Development Of Highly Sensitive And Selective Breathing Sensors Using Molecular Imprinted Filtering For Diabetic And Alcoholic Patients, Md. Saleh Akram Bhuiyan Jan 2017

Development Of Highly Sensitive And Selective Breathing Sensors Using Molecular Imprinted Filtering For Diabetic And Alcoholic Patients, Md. Saleh Akram Bhuiyan

Electronic Theses and Dissertations

Wellness sensor technology is an emerging diagnostic test research field, which mostly deal with the point of care of the patients in the recent days. Due to the lack of awareness from the patients, most diseases cannot be detected in due time. This led to worse conditions, such as diabetic and alcoholic syndrome. Therefore, many research groups have been working to develop portable sensor devices that can track serious diseases. These include diabetic and alcoholic biomarkers in breathing. These devices have very high selectivity and reliability. However, the major limitation of biomarkers is that it deals with the bio-molecular based …