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Nanozyme-Based Sensing Of Dopamine Using Cobalt-Doped Hydroxyapatite Nanocomposite From Waste Bones, Umar Nishan, Nighat Jabeen, Amir Badshah, Nawshad Muhammad, Mohibullah Shah, Irfan Ullah, Saifullah Afridi, Jibran Iqbal, Muhammad Asad, Riaz Ullah, Essam A. Ali, Sarfraz Ahmed, Suvash Chandra Ojha

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Dopamine is one of the most important neurotransmitters and plays a crucial role in various neurological, renal, and cardiovascular systems. However, the abnormal levels of dopamine mainly point to Parkinson’s, Alzheimer’s, cardiovascular diseases, etc. Hydroxyapatite (HAp), owing to its catalytic nature, nanoporous structure, easy synthesis, and biocompatibility, is a promising matrix material. These characteristics make HAp a material of choice for doping metals such as cobalt. The synthesized cobalt-doped hydroxyapatite (Co-HAp) was used as a colorimetric sensing platform for dopamine. The successful synthesis of the platform was confirmed by characterization with FTIR, SEM, EDX, XRD, TGA, etc. The platform demonstrated …