Open Access. Powered by Scholars. Published by Universities.®

Engineering Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 4 of 4

Full-Text Articles in Engineering

Near-Infrared Surface-Enhanced Fluorescence Using Silver Nanoparticles In Solution, Michael D. Furtaw Dec 2013

Near-Infrared Surface-Enhanced Fluorescence Using Silver Nanoparticles In Solution, Michael D. Furtaw

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

Fluorescence spectroscopy is a widely used detection technology in many research and clinical assays. Further improvement to assay sensitivity may enable earlier diagnosis of disease, novel biomarker discovery, and ultimately, improved outcomes of clinical care along with reduction in costs. Near-infrared, surface-enhanced fluorescence (NIR-SEF) is a promising approach to improve assay sensitivity via simultaneous increase in signal with a reduction in background. This dissertation describes research conducted with the overall goal to determine the extent to which fluorescence in solution may be enhanced by altering specific variables involved in the formation of plasmonactive nanostructures of dye-labeled protein and silver nanoparticles …


An Aggregation Procedure For Simulating Manufacturing Flow Line Models, Paul Savory, Gerald Mackulak Jan 1997

An Aggregation Procedure For Simulating Manufacturing Flow Line Models, Paul Savory, Gerald Mackulak

Department of Industrial and Management Systems Engineering: Faculty Publications

We develop a formal method for specifying an aggregate discrete-event simulation model of a production flow line manufacturing system. The methodology operates by aggregating production stations or resources of a flow line. Determining the specifications for representing the aggregated resources in a simulation model is the focus of our presentation. We test the methodology for a set of flow lines with exponentially distributed arrival and service times. Comparisons between analytical and simulation results indicate the aggregation approach is quite accurate for estimating average part cycle time.


A Robust Aggregation Approach To Simplification Of Manufacturing Flow Line Models, Paul Savory Nov 1993

A Robust Aggregation Approach To Simplification Of Manufacturing Flow Line Models, Paul Savory

Department of Industrial and Management Systems Engineering: Faculty Publications

One of the more difficult tasks facing a modeler in developing a simulation model of a discrete part manufacturing system is deciding at what level of abstraction to represent the resources of the system. For example, questions about plant capacity can be modeled with a simple model, whereas questions regarding the efficiency of different part scheduling rules can only be answered with a more detailed model. In developing a simulation model, most of the actual features of the system under study must be ignored and an abstraction must be developed. If done correctly, this idealization provides a useful approximation of …


A Robust Aggregation Approach To Simplification Of Manufacturing Flow Line Models, Paul Savory Nov 1993

A Robust Aggregation Approach To Simplification Of Manufacturing Flow Line Models, Paul Savory

Industrial and Management Systems Engineering: Presentations

One of the more difficult tasks facing a modeler in developing a simulation model of a discrete part manufacturing system is deciding at what level of abstraction to represent the resources of the system. For example, questions about plant capacity can be modeled with a simple model, whereas questions regarding the efficiency of different part scheduling rules can only be answered with a more detailed model. In developing a simulation model, most of the actual features of the system under study must be ignored and an abstraction must be developed. If done correctly, this idealization provides a useful approximation of …