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Method And Device For Removal Of Cryoprotectant From Cryopreserved Biological Cells And Tissues, Dayong Gao, Xiangdong Cui
Method And Device For Removal Of Cryoprotectant From Cryopreserved Biological Cells And Tissues, Dayong Gao, Xiangdong Cui
Biomedical Engineering Faculty Patents
Novel methods and devices for removing cryoprotectant from cryoprotectant-containing liquids, and from cells residing therein, are disclosed. In one aspect, the method comprises passing the cryoprotectant-containing liquid through at least one semipermeable hollow fiber membrane contained in a hollow module in a first direction, while passing a liquid which is substantially free of cryoprotectant through the hollow module in a second direction to remove cryoprotectant across a diffusion gradient. In another aspect, a device is described for removing cryoprotectant from a liquid, comprising a hollow module with at least one semipermeable hollow fiber membrane therein for accomplishing such counter-current diffusion …
Method For Improving Consolidation Of Powder Resin, David A. Pienkowski, Eric A. Grulke, Robert J. Jacob
Method For Improving Consolidation Of Powder Resin, David A. Pienkowski, Eric A. Grulke, Robert J. Jacob
Biomedical Engineering Faculty Patents
A method for improving consolidation of powder resin is provided. The method broadly includes the steps of: (1) sorting particles of the powder resin according to their diameter; (2) combining the sorted particles having a first diameter D1 with the sorted particles having a second diameter D2 so as to form a particle mixture; (3) applying a vibration to the particle mixture; (4) heating the particle mixture; and (5) delivering the particle mixture through a nozzle or into a mold. The particle diameters D1 and D2 are chosen so that once combined there is optimal close packing of the three-dimensional …
Method For Reducing The Generation Of Wear Particulates From An Implant, David A. Pienkowski, Kwon-Yong Lee
Method For Reducing The Generation Of Wear Particulates From An Implant, David A. Pienkowski, Kwon-Yong Lee
Biomedical Engineering Faculty Patents
A method is provided for reducing the amount of wear particulates generated by a total joint orthopaedic implant. The implant consists of two matched articulating components wherein at least one of the components is made of polymer or other material with similar physical properties. The method includes the steps of placing the total joint orthopaedic implant in a fluid bath and articulating the implant in the fluid bath for at least 1,000 cycles. The articulation may be performed in three stages. In the first, the implant is articulated under a load of substantially 0.1-500 Newtons with sliding speeds of substantially …
Method For Reducing The Generation Of Wear Particulates From An Implant, David A. Pienkowski
Method For Reducing The Generation Of Wear Particulates From An Implant, David A. Pienkowski
Biomedical Engineering Faculty Patents
A method is provided for reducing the amount of wear particulates generated by a total joint orthopaedic implant. The implant consists of two matched articulating components. The method includes the steps of placing the total joint orthopaedic implant in a fluid bath and articulating the implant in the fluid bath for at least 1,000 cycles. The articulation may be performed in three stages. In the first, the implant is articulated under a load of substantially 0.1-500 Newtons with sliding speeds of substantially 0.01-0.5 meters per second. During a second stage the articulation takes place under a load of substantially 200-2,500 …