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Selected Works

Philip A Allen

2015

Articles 1 - 2 of 2

Full-Text Articles in Engineering

Where Do We Stand On The Relationship Between Tau Biomarkers And Mild Cognitive Impairment?, Bryn Martin, Philip Allen Oct 2015

Where Do We Stand On The Relationship Between Tau Biomarkers And Mild Cognitive Impairment?, Bryn Martin, Philip Allen

Philip A Allen

We present an editorial on a recent publication by Amlien et al. [2013] in which diffusion tensor imaging (DTI) was used to quantify longitudinal decreases in fractional anisotropy (FA) and increased radial diffusivity (DR) in patients with mild cognitive impairment (MCI). These longitudinal alterations were found to be greater in MCI patients with high cerebrospinal fluid (CSF) tau levels at baseline and greater than healthy controls. Amlien et al. concluded that tau levels were an important early biomarker for predicting rate of disease progression and outcome. The results of this study are an interesting finding for possible predictive …


Task-Specific And General Cognitive Effects In Chiari Malformation Type I, Philip Allen, James Houston, Joshua Pollock, Christopher Buzzelli, Xuan Li, A. Harrington, Bryn Martin, Francis Loth, Mei-Ching Lien, Jahangir Maleki, Mark Luciano Oct 2015

Task-Specific And General Cognitive Effects In Chiari Malformation Type I, Philip Allen, James Houston, Joshua Pollock, Christopher Buzzelli, Xuan Li, A. Harrington, Bryn Martin, Francis Loth, Mei-Ching Lien, Jahangir Maleki, Mark Luciano

Philip A Allen

Our objective was to use episodic memory and executive function tests to determine whether or not Chiari Malformation Type I (CM) patients experience cognitive dysfunction.