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Articles 1 - 30 of 2118

Full-Text Articles in Engineering

Thrombogenicity Of Biodegradable Metals, D. E.J. Anderson, H. H. Le, H. Vu, J. Johnson, J. E. Aslan, J. Goldman, M. T. Hinds Aug 2024

Thrombogenicity Of Biodegradable Metals, D. E.J. Anderson, H. H. Le, H. Vu, J. Johnson, J. E. Aslan, J. Goldman, M. T. Hinds

Michigan Tech Publications, Part 2

Biodegradable metals offer a promising means to ameliorate many of the long-term risks associated with vascular devices made of conventional biostable stent metals. While numerous biodegradable metal alloys have been developed and characterized in animal models, knowledge of their blood reactivity and thrombogenicity remains unknown. Metal hemocompatibility is particularly valuable because current generation drug-eluting stents pose a significant long-term thrombosis risk. In this study, four pure metals, widely used as degradable base materials (Fe, Zn, Mg, and Mo), and three alloys commonly used in cardiovascular devices [NiTi, CoCr, and stainless steel (SS)] were evaluated. This work examined how each of …


Magnetization And Age Of Ca. 544 Ma Syenite, Eastern Canada: Evidence For Renewal Of The Geodynamo, Tinghong Zhou, Mauricio Ibañez-Mejia, Richard K. Bono, Rory D. Cottrell, Wouter Bleeker, Kenneth P. Kodama, Wentao Huang, Eric G. Blackman, Francis Nimmo, Aleksey Smirnov, John A. Tarduno Aug 2024

Magnetization And Age Of Ca. 544 Ma Syenite, Eastern Canada: Evidence For Renewal Of The Geodynamo, Tinghong Zhou, Mauricio Ibañez-Mejia, Richard K. Bono, Rory D. Cottrell, Wouter Bleeker, Kenneth P. Kodama, Wentao Huang, Eric G. Blackman, Francis Nimmo, Aleksey Smirnov, John A. Tarduno

Michigan Tech Publications, Part 2

The ca. 565 Ma Ediacaran geodynamo was highly unusual, producing an ultralow field 10 times weaker than present-day value of 8 x 1022 A m2. A ∼5 times rise in field strength is seen in time-averaged single crystal paleointensity data of ca. 532 Ma Early Cambrian anorthosites of Oklahoma (USA). The field increase could record the onset of inner core nucleation predicted by thermal evolution and numerical dynamo models. Here, we examine the renewal of the geodynamo through zircon U-Pb geochronology and single crystal paleointensity studies of plagioclase from the Chatham-Grenville syenite intrusion in the Grenville Province (Canada). U-Pb data …


Laboratory Evaluation And Field Demonstration Of Cold In-Place Recycling Asphalt Mixture In Michigan Low-Volume Road, Dongzhao Jin, Lei Yin, Lance Malburg, Zhanping You Jul 2024

Laboratory Evaluation And Field Demonstration Of Cold In-Place Recycling Asphalt Mixture In Michigan Low-Volume Road, Dongzhao Jin, Lei Yin, Lance Malburg, Zhanping You

Michigan Tech Publications, Part 2

Cold-in place recycling (CIR) is a promising technology for the rehabilitation of asphalt pavements. However, the CIR asphalt pavement constructed in the field often has high air voids due to the presence of moisture during construction, and the moisture susceptibility of the pavement is crucial in determining its service life. Therefore, the objective of this research was to assess the laboratory performance of CIR asphalt mixes under freeze-thaw conditions (The mix prior to being subjected to freezing and thawing is labeled as "dry condition", while the mix that was placed in a refrigerator at –18 °C for 16 h and …


Aerobic Exercise Improves Depressive Symptoms In The Unilateral 6-Ohda-Lesioned Rat Model Of Parkinson's Disease, Hannah Loughlin, Jacob Jackson, Chloe Looman, Alayna Starll, Jeremy Goldman, Zhiying Shan, Chunxiu Yu Jun 2024

Aerobic Exercise Improves Depressive Symptoms In The Unilateral 6-Ohda-Lesioned Rat Model Of Parkinson's Disease, Hannah Loughlin, Jacob Jackson, Chloe Looman, Alayna Starll, Jeremy Goldman, Zhiying Shan, Chunxiu Yu

Michigan Tech Publications, Part 2

Aerobic exercise has been shown to have established benefits on motor function in Parkinson's disease (PD). However, the impact of exercise on depressive symptoms in PD remains unclear. This study aimed to investigate the effects of regular exercise, specifically using a forced running wheel, on both motor performance and the prevalence of depression in a unilateral 6-OHDA-lesioned rat model of PD. The behavioral outcomes of exercise were assessed through the rotarod test (RT), forelimb adjusting step test (FAST), sucrose consumption test (SCT), and novelty sucrose splash test (NSST). Our data revealed evident depressive symptoms in the PD animals, characterized by …


Me-Em Enewsbrief, Mar 2024, Department Of Mechanical Engineering-Engineering Mechanics, Michigan Technological University May 2024

Me-Em Enewsbrief, Mar 2024, Department Of Mechanical Engineering-Engineering Mechanics, Michigan Technological University

Department of Mechanical Engineering-Engineering Mechanics eNewsBrief

No abstract provided.


Near-Collapse Of The Geomagnetic Field May Have Contributed To Atmospheric Oxygenation And Animal Radiation In The Ediacaran Period, Wentao Huang, John A. Tarduno, Tinghong Zhou, Mauricio Ibañez-Mejia, Laércio Dal Olmo-Barbosa, Edinei Koester, Eric G. Blackman, Aleksey V. Smirnov, Gabriel Ahrendt, Rory D. Cottrell, Kenneth P. Kodama, Richard K. Bono, David G. Sibeck, Yong Xiang Li, Francis Nimmo, Shuhai Xiao, Michael K. Watkeys May 2024

Near-Collapse Of The Geomagnetic Field May Have Contributed To Atmospheric Oxygenation And Animal Radiation In The Ediacaran Period, Wentao Huang, John A. Tarduno, Tinghong Zhou, Mauricio Ibañez-Mejia, Laércio Dal Olmo-Barbosa, Edinei Koester, Eric G. Blackman, Aleksey V. Smirnov, Gabriel Ahrendt, Rory D. Cottrell, Kenneth P. Kodama, Richard K. Bono, David G. Sibeck, Yong Xiang Li, Francis Nimmo, Shuhai Xiao, Michael K. Watkeys

Michigan Tech Publications, Part 2

Earth’s magnetic field was in a highly unusual state when macroscopic animals of the Ediacara Fauna diversified and thrived. Any connection between these events is tantalizing but unclear. Here, we present single crystal paleointensity data from 2054 and 591 Ma pyroxenites and gabbros that define a dramatic intensity decline, from a strong Proterozoic field like that of today, to an Ediacaran value 30 times weaker. The latter is the weakest time-averaged value known to date and together with other robust paleointensity estimates indicate that Ediacaran ultra-low field strengths lasted for at least 26 million years. This interval of ultra-weak magnetic …


To What Extent Do Water Reuse Treatments Reduce Antibiotic Resistance Indicators? A Comparison Of Two Full-Scale Systems, Ishi Keenum, Jeanette Calarco, Haniyyah Majeed, E. Eldridge Hager-Soto, Charles Bott, Emily Garner, Valerie J. Harwood, Amy Pruden May 2024

To What Extent Do Water Reuse Treatments Reduce Antibiotic Resistance Indicators? A Comparison Of Two Full-Scale Systems, Ishi Keenum, Jeanette Calarco, Haniyyah Majeed, E. Eldridge Hager-Soto, Charles Bott, Emily Garner, Valerie J. Harwood, Amy Pruden

Michigan Tech Publications, Part 2

Water reuse is an essential strategy for reducing water demand from conventional sources, alleviating water stress, and promoting sustainability, but understanding the effectiveness of associated treatment processes as barriers to the spread of antibiotic resistance is an important consideration to protecting human health. We comprehensively evaluated the reduction of antibiotic resistance genes (ARGs) and antibiotic-resistant bacteria (ARB) in two field-operational water reuse systems with distinct treatment trains, one producing water for indirect potable reuse (ozone/biologically-active carbon/granular activated carbon) and the other for non-potable reuse (denitrification-filtration/chlorination) using metagenomic sequencing and culture. Relative abundances of total ARGs/clinically-relevant ARGs and cultured ARB were …


Optimal Molecular Dynamics System Size For Increased Precision And Efficiency For Epoxy Materials, Khatereh Kashmari, Sagar Patil, Josh Kemppainen, Shankara Gowtham, Gregory Odegard Apr 2024

Optimal Molecular Dynamics System Size For Increased Precision And Efficiency For Epoxy Materials, Khatereh Kashmari, Sagar Patil, Josh Kemppainen, Shankara Gowtham, Gregory Odegard

Michigan Tech Publications, Part 2

Molecular dynamics (MD) simulation is an important tool for predicting thermo-mechanical properties of polymer resins at the nanometer length scale, which is particularly important for efficient computationally driven design of advanced composite materials and structures. Because of the statistical nature of modeling amorphous materials on the nanometer length scale, multiple MD models (replicates) are typically built and simulated for statistical sampling of predicted properties. Larger replicates generally provide higher precision in the predictions but result in higher simulation times. Unfortunately, there is insufficient information in the literature to establish guidelines between MD model size and the resulting precision in predicted …


Data Set: The Analysis Of Lava Flow Path Using Remote Sensing Techniques And Geomorphological Techniques: The Case Of Volcano Eruptions In Afar Region Of Ethiopia, Oluwatosin Ayo, Jae Sung Kim Apr 2024

Data Set: The Analysis Of Lava Flow Path Using Remote Sensing Techniques And Geomorphological Techniques: The Case Of Volcano Eruptions In Afar Region Of Ethiopia, Oluwatosin Ayo, Jae Sung Kim

Michigan Tech Research Data

Natural disasters pose significant threats to the environment and make land unsuitable for man. The lava from volcanic eruptions rapidly moves on the Earth surface and affects both natural and man-made features on the Earth. Remote sensing is relevant in extracting information about the areas affected by lava flows without physically visiting such areas. The objective of this study is to develop a workflow for determining the optimal ground sample distance of a digital elevation model to delineate the lava flow paths using object-based image analysis and geomorphologic analysis. For the experiment, the satellite images and digital elevation model of …


Soil Stabilization With Gypsum: A Review, Yasaman Abdolvand, Mohammadhossein Sadeghiamirshahidi Apr 2024

Soil Stabilization With Gypsum: A Review, Yasaman Abdolvand, Mohammadhossein Sadeghiamirshahidi

Michigan Tech Publications, Part 2

The demand for sustainable ground improvement methods is rising as urban development expands into areas with challenging soil conditions. Traditional approaches, mostly reliant on cement and lime, contribute significantly to anthropogenic greenhouse gas emissions. Researchers, therefore, are constantly searching for new environmentally friendly stabilization methods to improve the engineering properties of soils. One alternative material used for this purpose is gypsum in its hydrated and dehydrated (hemihydrate/anhydrate) states. Not only can natural gypsum be used for ground improvement but also industrial waste and by-products (e.g. used or waste plasterboard, phosphogypsum, flue gas desulfurization gypsum, titanium dioxide production gypsum by-product) can …


Synergy Between Ca2+ And High Ionic Field-Strength Cations During The Corrosion Of Alkali Aluminoborosilicate Glasses In Hyper-Alkaline Media, Qianhui Qin, Nicholas Stone-Weiss, Nian Shi, Pinaki Mukherjee, Jinjun Ren, Ashutosh Goel Apr 2024

Synergy Between Ca2+ And High Ionic Field-Strength Cations During The Corrosion Of Alkali Aluminoborosilicate Glasses In Hyper-Alkaline Media, Qianhui Qin, Nicholas Stone-Weiss, Nian Shi, Pinaki Mukherjee, Jinjun Ren, Ashutosh Goel

Michigan Tech Publications, Part 2

One major factor impeding the design of nuclear waste glasses with enhanced waste loadings is our insufficient understanding of their composition–structure–durability relationships, specifically in the environments the waste form is expected to encounter in a geological repository. In particular, the high field-strength cations (HFSCs) are an integral component of most waste streams. However, their impact on the long-term performance of the glassy waste form remains mostly undeciphered. In this context, the present study aims to understand the impact of some HFSCs (i.e., Nb5+, Zr4+, Ti4+, and La3+) on the dissolution behavior of alkali/alkaline-earth aluminoborosilicate-based model nuclear waste glasses in hyper-alkaline …


Deciphering The Controlling Factors For Phase Transitions In Zeolitic Imidazolate Frameworks, Tao Du, Shanwu Li, Sudheer Ganisetti, Mathieu Bauchy, Yuanzheng Yue, Morten M. Smedskjaer Apr 2024

Deciphering The Controlling Factors For Phase Transitions In Zeolitic Imidazolate Frameworks, Tao Du, Shanwu Li, Sudheer Ganisetti, Mathieu Bauchy, Yuanzheng Yue, Morten M. Smedskjaer

Michigan Tech Publications, Part 2

Zeolitic imidazolate frameworks (ZIFs) feature complex phase transitions, including polymorphism, melting, vitrification, and polyamorphism. Experimentally probing their structural evolution during transitions involving amorphous phases is a significant challenge, especially at the medium-range length scale. To overcome this challenge, here we first train a deep learning-based force field to identify the structural characteristics of both crystalline and non-crystalline ZIF phases. This allows us to reproduce the structural evolution trend during the melting of crystals and formation of ZIF glasses at various length scales with an accuracy comparable to that of ab initio molecular dynamics, yet at a much lower computational cost. …


Characterization Of Oscillatory Response Of Light-Weight Wind Turbine Rotors Under Controlled Gust Pulses, Fernando Ponta, Alayna Farrell, Apurva Baruah, North Yates Mar 2024

Characterization Of Oscillatory Response Of Light-Weight Wind Turbine Rotors Under Controlled Gust Pulses, Fernando Ponta, Alayna Farrell, Apurva Baruah, North Yates

Michigan Tech Publications, Part 2

Given the industry-wide trend of continual increases in the size of utility-scale wind turbines, a point will come where reductions will need to be made in terms of the weight of the turbine’s blades to ensure they can be as long as needed without sacrificing structural stability. One such technique that may be considered is to decrease the material used for the shell and spar cap. While this will solve the weight issue, it creates a new one entirely—less material for the shell and spar cap will in turn create blades that are more flexible than what is currently used. …


Sanitation In Urban Areas May Limit The Spread Of Antimicrobial Resistance Via Flies, Drew Capone, Oliver Cumming, Abeoseh Flemister, Victor Ilevbare, Seth R. Irish, Ishi Keenum, Jackie Knee, Rassul Nala, Joe Brown Mar 2024

Sanitation In Urban Areas May Limit The Spread Of Antimicrobial Resistance Via Flies, Drew Capone, Oliver Cumming, Abeoseh Flemister, Victor Ilevbare, Seth R. Irish, Ishi Keenum, Jackie Knee, Rassul Nala, Joe Brown

Michigan Tech Publications, Part 2

Synanthropic filth flies are common where sanitation is poor and fecal wastes are accessible to them. These flies have been proposed as mechanical vectors for the localized transport of fecal microbes including antimicrobial resistant (AMR) organisms and associated antimicrobial resistance genes (ARGs), increasing exposure risks. We evaluated whether an onsite sanitation intervention in Maputo, Mozambique reduced the concentration of enteric bacteria and the frequency of detection of ARGs carried by flies collected in household compounds of low-income neighborhoods. Additionally, we assessed the phenotypic resistance profile of Enterobacteriaceae isolates recovered from flies during the pre-intervention phase. After fly enumeration at study …


Increasing The Dissolution Rate Of Polystyrene Waste In Solvent-Based Recycling, Rita Kol, Ruben Denolf, Gwendoline Bernaert, Dave Manhaeghe, Ezra Bar Ziv, George W. Huber, Norbert Niessner, Michiel Verswyvel, Angeliki Lemonidou, Dimitris S. Achilias, Steven De Meester Mar 2024

Increasing The Dissolution Rate Of Polystyrene Waste In Solvent-Based Recycling, Rita Kol, Ruben Denolf, Gwendoline Bernaert, Dave Manhaeghe, Ezra Bar Ziv, George W. Huber, Norbert Niessner, Michiel Verswyvel, Angeliki Lemonidou, Dimitris S. Achilias, Steven De Meester

Michigan Tech Publications, Part 2

Solvent-based recycling of plastic waste is a promising approach for cleaning polymer chains without breaking them. However, the time required to actually dissolve the polymer in a lab environment can take hours. Different factors play a role in polymer dissolution, including temperature, turbulence, and solvent properties. This work provides insights into bottlenecks and opportunities to increase the dissolution rate of polystyrene in solvents. The paper starts with a broad solvent screening in which the dissolution times are compared. Based on the experimental results, a multiple regression model is constructed, which shows that within several solvent properties, the viscosity of the …


Experimental Investigation Of Long-Term Performance Of Fiber-Reinforced Epoxy And Polyurethane Polymer Composites, Abdel Hamid I. Mourad, Amir Hussain Idrisi, Asima Zahoor, Muhammad M. Sherif, Beckry M. Abdel-Magid Mar 2024

Experimental Investigation Of Long-Term Performance Of Fiber-Reinforced Epoxy And Polyurethane Polymer Composites, Abdel Hamid I. Mourad, Amir Hussain Idrisi, Asima Zahoor, Muhammad M. Sherif, Beckry M. Abdel-Magid

Michigan Tech Publications, Part 2

The primary challenge encountered by polymers and their composites when exposed to saline water is their inadequate ability to withstand wear and tear over time. With a potential to replace conventional materials the long-term performance of FRP composites is still a novice area. This manuscript thus, reports an experimental investigation and prediction of the durability of fiber-reinforced polymer composites exposed to seawater at different temperatures. E-glass/epoxy and E-glass/polyurethane samples were exposed to 23 °C, 45 °C and 65 °C seawater for up to 2700 days (90 months). Tensile tests evaluated the mechanical performance of the composite as a function of …


Simulation Of The Multi-Wake Evolution Of Two Sandia National Labs/National Rotor Testbed Turbines Operating In A Tandem Layout, Apurva Baruah, Fernando L. Ponta, Alayna Farrell Feb 2024

Simulation Of The Multi-Wake Evolution Of Two Sandia National Labs/National Rotor Testbed Turbines Operating In A Tandem Layout, Apurva Baruah, Fernando L. Ponta, Alayna Farrell

Michigan Tech Publications, Part 2

The future of wind power systems deployment is in the form of wind farms comprised of scores of such large turbines, most likely at offshore locations. Individual turbines have grown in span from a few tens of meters to today’s large turbines with rotor diameters that dwarf even the largest commercial aircraft. These massive dynamical systems present unique challenges at scales unparalleled in prior applications of wind science research. Fundamental to this effort is the understanding of the wind turbine wake and its evolution. Furthermore, the optimization of the entire wind farm depends on the evolution of the wakes of …


Association Of Bovine Arch Anatomy With Incident Stroke After Transcatheter Aortic Valve Replacement, Gerardo V. Lo Russo, Hasan S. Alarouri, Abdulah Al-Abcha, Brennan Vogl, Abdulah Mahayni, Agata Sularz, Hoda Hatoum, Jeremy Collins, Juan A. Crestanello, Mohamad Alkhouli Feb 2024

Association Of Bovine Arch Anatomy With Incident Stroke After Transcatheter Aortic Valve Replacement, Gerardo V. Lo Russo, Hasan S. Alarouri, Abdulah Al-Abcha, Brennan Vogl, Abdulah Mahayni, Agata Sularz, Hoda Hatoum, Jeremy Collins, Juan A. Crestanello, Mohamad Alkhouli

Michigan Tech Publications, Part 2

BACKGROUND: Acute ischemic stroke complicates 2 % to 3 % of transcatheter aortic valve replacements (TAVRs). This study aimed to identify the aortic anatomic correlates in patients after TAVR stroke. METHODS AND RESULTS: This is a single-center, retrospective study of patients who underwent TAVR at the Mayo Clinic between 2012 and 2022. The aortic arch morphology was determined via a manual review of the pre-TAVR computed tomography images. An "a priori" approach was used to select the covariates for the following: (1) the logistic regression model assessing the association between a bovine arch and periprocedural stroke (defined as stroke within …


Progress In Energy: Usa–Canada Special Issue On Energy, Yun Hang Hu Feb 2024

Progress In Energy: Usa–Canada Special Issue On Energy, Yun Hang Hu

Michigan Tech Publications, Part 2

No abstract provided.


High Temperatures And Low Soil Moisture Synergistically Reduce Switchgrass Yields From Marginal Field Sites And Inhibit Fermentation, Sarvada Chipkar, Kevin Kahmark, Sven Bohm, Mir Zaman Hussain, Leela Joshi, Karleigh M. Krieg, Jacob Aguado, Jasmine Cassidy, Pablo Lozano, Kevin Garland, Andrea Senyk, Derek J. Debrauske, Elizabeth Whelan, Morgan Davies, Paul Urban, G. Philip Robertson, Trey K. Sato, Stephen K. Hamilton, Kurt D. Thelen, Rebecca Ong Feb 2024

High Temperatures And Low Soil Moisture Synergistically Reduce Switchgrass Yields From Marginal Field Sites And Inhibit Fermentation, Sarvada Chipkar, Kevin Kahmark, Sven Bohm, Mir Zaman Hussain, Leela Joshi, Karleigh M. Krieg, Jacob Aguado, Jasmine Cassidy, Pablo Lozano, Kevin Garland, Andrea Senyk, Derek J. Debrauske, Elizabeth Whelan, Morgan Davies, Paul Urban, G. Philip Robertson, Trey K. Sato, Stephen K. Hamilton, Kurt D. Thelen, Rebecca Ong

Michigan Tech Publications, Part 2

‘Marginal lands’ are low productivity sites abandoned from agriculture for reasons such as low or high soil water content, challenging topography, or nutrient deficiency. To avoid competition with crop production, cellulosic bioenergy crops have been proposed for cultivation on marginal lands, however on these sites they may be more strongly affected by environmental stresses such as low soil water content. In this study we used rainout shelters to induce low soil moisture on marginal lands and determine the effect of soil water stress on switchgrass growth and the subsequent production of bioethanol. Five marginal land sites that span a latitudinal …


Analysis Of Wind Turbine Wake Dynamics By A Gaussian-Core Vortex Lattice Technique, Apurva Baruah, Fernando L. Ponta Feb 2024

Analysis Of Wind Turbine Wake Dynamics By A Gaussian-Core Vortex Lattice Technique, Apurva Baruah, Fernando L. Ponta

Michigan Tech Publications, Part 2

The development and deployment of the next generation of wind energy systems calls for simulation tools that model the entire wind farm while balancing accuracy and computational cost. A full-system wind farm simulation must consider the atmospheric inflow, the wakes and consequent response of the multiple turbines, and the implementation of the appropriate farm-collective control strategies that optimize the entire wind farm’s output. In this article, we present a novel vortex lattice model that enables the effective representation of the complex vortex wake dynamics of the turbines in a farm subject to transient inflow conditions. This work extends the capabilities …


Low Shear In Short-Term Impacts Endothelial Cell Traction And Alignment In Long-Term, Mohanish K. Chandurkar, Nikhil Mittal, Shaina P. Royer-Weeden, Steven D. Lehmann, Yeonwoo Rho, Sangyoon J. Han Feb 2024

Low Shear In Short-Term Impacts Endothelial Cell Traction And Alignment In Long-Term, Mohanish K. Chandurkar, Nikhil Mittal, Shaina P. Royer-Weeden, Steven D. Lehmann, Yeonwoo Rho, Sangyoon J. Han

Michigan Tech Publications, Part 2

Within the vascular system, endothelial cells (ECs) are exposed to fluid shear stress (FSS), a mechanical force exerted by blood flow that is critical for regulating cellular tension and maintaining vascular homeostasis. The way ECs react to FSS varies significantly; while high, laminar FSS supports vasodilation and suppresses inflammation, low or disturbed FSS can lead to endothelial dysfunction and increase the risk of cardiovascular diseases. Yet, the adaptation of ECs to dynamically varying FSS remains poorly understood. This study focuses on the dynamic responses of ECs to brief periods of low FSS, examining its impact on endothelial traction—a measure of …


Low Shear In Short-Term Impacts Endothelial Cell Traction And Alignment In Long-Term, Mohanish Chandurkar, Nikhil Mittal, Shaina P. Royer-Weeden, Steven D. Lehmann, Yeonwoo Rho, Sangyoon J. Han Feb 2024

Low Shear In Short-Term Impacts Endothelial Cell Traction And Alignment In Long-Term, Mohanish Chandurkar, Nikhil Mittal, Shaina P. Royer-Weeden, Steven D. Lehmann, Yeonwoo Rho, Sangyoon J. Han

Michigan Tech Publications, Part 2

Within the vascular system, endothelial cells (ECs) are exposed to fluid shear stress (FSS), a mechanical force exerted by blood flow that is critical for regulating cellular tension and maintaining vascular homeostasis. The way ECs react to FSS varies significantly; while high, laminar FSS supports vasodilation and suppresses inflammation, low or disturbed FSS can lead to endothelial dysfunction and increase the risk of cardiovascular diseases. Yet, the adaptation of ECs to dynamically varying FSS remains poorly understood. This study focuses on the dynamic responses of ECs to brief periods of low FSS, examining its impact on endothelial traction-a measure of …


Is Geology Accreditation Needed? It Is Already Here!, Laurie C. Anderson, John S. Gierke, Jeffrey B. Connelly Feb 2024

Is Geology Accreditation Needed? It Is Already Here!, Laurie C. Anderson, John S. Gierke, Jeffrey B. Connelly

Michigan Tech Publications, Part 2

No abstract provided.


Research And Comparison Of Pavement Performance Prediction Based On Neural Networks And Fusion Transformer Architecture, Hui Yao, Ke Han, Yanhao Liu, Dawei Wang, Zhanping You Jan 2024

Research And Comparison Of Pavement Performance Prediction Based On Neural Networks And Fusion Transformer Architecture, Hui Yao, Ke Han, Yanhao Liu, Dawei Wang, Zhanping You

Michigan Tech Publications, Part 2

The decision-making process for pavement maintenance from a scientific perspective is based on accurate predictions of pavement performance. To improve the rationality of pavement performance indicators, comprehensive consideration of various influencing factors is necessary. To this end, four typical pavement performance indicators (i.e., Rutting Depth, International Roughness Index, Longitudinal Cracking, and Alligator Cracking) were predicted using the Long Term Pavement Performance (LTPP) database. Two types of data, i.e., local input variables and global input variables, were selected, and S-ANN and L-ANN models were constructed using a fully connected neural network. A comparative analysis of the predictive outcomes reveals the superior …


Polymerizing Actin Regulates Myosin-Independent Mechanosensing By Modulating Actin Elasticity And Flow Fluctuation, Nikhil Mittal, Etienne Michels, Kathleen Pakenas, Shaina P. Royer-Weeden, Sangyoon J. Han Jan 2024

Polymerizing Actin Regulates Myosin-Independent Mechanosensing By Modulating Actin Elasticity And Flow Fluctuation, Nikhil Mittal, Etienne Michels, Kathleen Pakenas, Shaina P. Royer-Weeden, Sangyoon J. Han

Michigan Tech Publications, Part 2

The stiffness of the extracellular matrix induces differential tension within integrin-based adhesions. However, it has been unclear if the stiffness-dependent differential tension is induced solely by myosin activity. Here, we report that in the absence of myosin contractility, 3T3 fibroblasts still transmit stiffness-dependent differential levels of traction. This myosin-independent differential traction is regulated by polymerizing actin assisted by actin nucleators Arp2/3 and formin where formin has stronger contribution than Arp2/3. Interestingly, we report a four-fold reduction in traction of cells when both Arp2/3 and myosin were inhibited, compared to cells with only myosin inhibition, while there was only a slight …


Heterologous Expression Of Arabidopsis Laccase2, Laccase4 And Peroxidase52 Driven Under Developing Xylem Specific Promoter Dx15 Improves Saccharification In Populus, Yogesh Ahlawat, Ajaya K. Biswal, Sarahani Harun, Anne E. Harman-Ware, Crissa Doeppke, Nisha Sharma, Chandrashekhar P. Joshi, Bertrand B. Hankoua Jan 2024

Heterologous Expression Of Arabidopsis Laccase2, Laccase4 And Peroxidase52 Driven Under Developing Xylem Specific Promoter Dx15 Improves Saccharification In Populus, Yogesh Ahlawat, Ajaya K. Biswal, Sarahani Harun, Anne E. Harman-Ware, Crissa Doeppke, Nisha Sharma, Chandrashekhar P. Joshi, Bertrand B. Hankoua

Michigan Tech Publications, Part 2

Background: Secondary cell wall holds considerable potential as it has gained immense momentum to replace the lignocellulosic feedstock into fuels. Lignin one of the components of secondary cell wall tightly holds the polysaccharides thereby enhancing the recalcitrance and complexity in the biomass. Laccases (LAC) and peroxidases (PRX) are the major phenyl-oxidases playing key functions during the polymerization of monolignols into lignin. Yet, the functions of laccase and peroxidases gene families remained largely unknown. Hence, the objective of this conducted study is to understand the role of specific LAC and PRX in Populus wood formation and to further investigate how the …


Myosin-Independent Stiffness Sensing By Fibroblasts Is Regulated By The Viscoelasticity Of Flowing Actin, Nikhil Mittal, Etienne B. Michels, Andrew E. Massey, Yunxiu Qiu, Shaina P. Royer-Weeden, Bryan R. Smith, Alexander X. Cartagena-Rivera, Sangyoon J. Han Jan 2024

Myosin-Independent Stiffness Sensing By Fibroblasts Is Regulated By The Viscoelasticity Of Flowing Actin, Nikhil Mittal, Etienne B. Michels, Andrew E. Massey, Yunxiu Qiu, Shaina P. Royer-Weeden, Bryan R. Smith, Alexander X. Cartagena-Rivera, Sangyoon J. Han

Michigan Tech Publications, Part 2

The stiffness of the extracellular matrix induces differential tension within integrin-based adhesions, triggering differential mechanoresponses. However, it has been unclear if the stiffness-dependent differential tension is induced solely by myosin activity. Here, we report that in the absence of myosin contractility, 3T3 fibroblasts still transmit stiffness-dependent differential levels of traction. This myosin-independent differential traction is regulated by polymerizing actin assisted by actin nucleators Arp2/3 and formin where formin has a stronger contribution than Arp2/3 to both traction and actin flow. Intriguingly, despite only slight changes in F-actin flow speed observed in cells with the combined inhibition of Arp2/3 and myosin …


Suitability Of The Height Above Nearest Drainage (Hand) Model For Flood Inundation Mapping In Data-Scarce Regions: A Comparative Analysis With Hydrodynamic Models, Navin Tony Thalakkottukara, Jobin Thomas, Melanie Watkins, Benjamin C. Holland, Thomas Oommen, Himanshu Grover Jan 2024

Suitability Of The Height Above Nearest Drainage (Hand) Model For Flood Inundation Mapping In Data-Scarce Regions: A Comparative Analysis With Hydrodynamic Models, Navin Tony Thalakkottukara, Jobin Thomas, Melanie Watkins, Benjamin C. Holland, Thomas Oommen, Himanshu Grover

Michigan Tech Publications, Part 2

Unprecedented floods from extreme rainfall events worldwide emphasize the need for flood inundation mapping for floodplain management and risk reduction. Access to flood inundation maps and risk evaluation tools remains challenging in most parts of the world, particularly in rural regions, leading to decreased flood resilience. The use of hydraulic and hydrodynamic models in rural areas has been hindered by excessive data and computational requirements. In this study, we mapped the flood inundation in Huron Creek watershed, Michigan, USA for an extreme rainfall event (1000-year return period) that occurred in 2018 (Father’s Day Flood) using the Height Above Nearest Drainage …


Thermo-Photo Catalytic Anode Process For Carbonate-Superstructured Solid Fuel Cells, Hanrui Su, Yun Hang Hu Jan 2024

Thermo-Photo Catalytic Anode Process For Carbonate-Superstructured Solid Fuel Cells, Hanrui Su, Yun Hang Hu

Michigan Tech Publications, Part 2

Converting hydrocarbons and greenhouse gases (i.e., carbon dioxide, CO2) directly into electricity through fuel cells at intermediate temperatures (450 to 550 °C) remains a significant challenge, primarily due to the sluggish activation of C-H and C=O bonds. Here, we demonstrated a unique strategy to address this issue, in which light illumination was introduced into the thermal catalytic CO2reforming of ethane in the anode as a unique thermo-photo anode process for carbonate-superstructured solid fuel cells. The light-enhanced fuel activation led to excellent cell performance with a record-high peak power density of 168 mW cm-2at an intermediate temperature of 550 °C. Furthermore, …