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Cleveland State University

2018

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Articles 31 - 60 of 72

Full-Text Articles in Engineering

The Effect Of Cognitive Limb Embodiment On Vascular Physiological Response, Hala Elsir Mustafa Osman Jan 2018

The Effect Of Cognitive Limb Embodiment On Vascular Physiological Response, Hala Elsir Mustafa Osman

ETD Archive

The rubber hand illusion (RHI) is a visual-tactile perceptual illusion commonly used to study body ownership. In this paradigm, a rubber hand is positioned in front of a participant, and the person’s real hand is hidden from sight behind a barrier. When the real hand and the rubber hand are stroked synchronously, individuals perceive the rubber hand as if it were their own; it becomes “embodied.” This illusory experience of body ownership is associated with multimodal integration of touch and vision. From these visual-tactile-cognitive mechanisms, we establish that our hands belong to us when what we see matches what we …


Drughelp.Care – A Web Application For The Discovery Of Drug Addiction Treatment Facilities, Sachin Hiriyanna Jan 2018

Drughelp.Care – A Web Application For The Discovery Of Drug Addiction Treatment Facilities, Sachin Hiriyanna

ETD Archive

One of the current and biggest problems in the system of emergency care for the drug overdose epidemic, is the failure of information delivery on nearby treatment facilities. Even though some initiatives on the internet tried to solve this issue, they either failed in delivering the information or in providing ease of usability. This thesis research aims to develop a web application which, 1. Delivers a highly accurate, easy-to-understand and targeted information in a timely manner for drug abusers and their well-wishers. 2. Provides an eco-system for the treatment facilities with an easy-to-use backend to constantly update their complex information …


Color Removal From Combined Dye And Fruit Nectar Wastewater Using Adsorption And Microfiltration, Oluwatobiloba A. Akinwande Jan 2018

Color Removal From Combined Dye And Fruit Nectar Wastewater Using Adsorption And Microfiltration, Oluwatobiloba A. Akinwande

ETD Archive

Pollution of the waterways is a great challenge of the 21st century. Textile effluents contain compounds which have the capacity to cause more harm when ingested. There are many dye removal technologies like coagulation, photo oxidation which help to remove color from dye wastewater. The use of adsorption to remove color from dye wastewater has been used for many centuries. Activated carbon can efficiently remove color from dye wastewater but it is very expensive and so different researches have been conducted to get the adsorption capacity of different forms of adsorbents. These adsorbents can be gotten from agricultural waste, biomass, …


Color Removal And Treatment Of Dye And Sugar Waste Water Using Low Cost Adsorbents, Saisantosh Vamshi Harsha Madiraju Jan 2018

Color Removal And Treatment Of Dye And Sugar Waste Water Using Low Cost Adsorbents, Saisantosh Vamshi Harsha Madiraju

ETD Archive

This study was undertaken to determine the treatment of wastewater from dye and sugar industry for removal of color. This specific treatment consists of adsorption using low cost adsorbents and micro filtration using whatman-41 micro filters. Considerations of this treatment process is to take the samples using batch adsorption and avoid coagulation with further dilution. Numerous runs were made with the ideal waste samples prepared in the laboratory. As a first step in the study different dyes were considered using different concentrations of sugar wastewater. Samples were treated with three different low-cost adsorbents. These treated samples using low cost adsorbents …


A Transformative Process Control Solution, Simone Castanho Nobrega De Almedia Soares Jan 2018

A Transformative Process Control Solution, Simone Castanho Nobrega De Almedia Soares

ETD Archive

Knowing that a technology invented almost hundred years ago (PID controller) is still dominating industrial process control, a historical review was done to understand how the control field evolved. Model dependency and high level of mathematics appear as the main reasons that prevent other technologies from penetrating the engineering practice. A relatively novel methodology introduced by J. Han in 1998 called Active Disturbance Rejection Control (ADRC) came with characteristics that matches process control needs and restrictions on model dependency. This study will present a transformative solution for process control based on that. The control algorithm is designed and discretized for …


High-Throughput Metabolism-Induced Toxicity Assays On A 384-Pillar Plate, Sooyeion Kang Jan 2018

High-Throughput Metabolism-Induced Toxicity Assays On A 384-Pillar Plate, Sooyeion Kang

ETD Archive

The U.S Environmental Protection Agency (EPA) launched the Transform Tox Testing Challenge in 2016 with the goal of developing practical methods that can be integrated into conventional high-throughput screening (HTS) assays to better predict the toxicity of parent compounds and their metabolites in vivo. In response to this need and to retrofit existing HTS assays for assessing metabolism-induced toxicity of compounds, we have developed a 384-pillar plate that is complementary to traditional 384-well plates and ideally suited for culturing human cells in three dimensions (3D) at a microscale. Briefly, human embryonic kidney (HEK) 293 cells in a mixture of alginate …


Designing Novel Grooved Pallets For Industrial Application, Mirza Mohammed Abdullah Baig Jan 2018

Designing Novel Grooved Pallets For Industrial Application, Mirza Mohammed Abdullah Baig

ETD Archive

The purpose of this study was to model an improved pallet design which could overcome the drawbacks and failures of the pallets available in the market today. The new modeled pallets were designed to improve the capacity of the individual pallets and thereby increase the efficiency of the material handling process. The new modeled pallets were also designed with the aim to replace the racking system used for storage in the warehouse industry. The study was performed using two finite element analysis software, SOLIDWORKS and ANSYS, as analysis tools to study the behavior of the design under various real world …


Color Removal Of Dye And Milk Wastewater Using Peanut Hull By The Process Of Adsorption, Venkatesh Kummarakuntla Jan 2018

Color Removal Of Dye And Milk Wastewater Using Peanut Hull By The Process Of Adsorption, Venkatesh Kummarakuntla

ETD Archive

Dairy industry is one of the major industries from which organic wastewater is produced and released into the water bodies. Textile industries also generate considerable amount of dye wastewater that effect the water quality standards. Various treatment techniques are adopted to treat the wastewater. Adsorption is one of the low-cost treatment processes to treat the textile and milk wastewater. This thesis focuses on the treatment of combined dye and milk wastewater using the process of adsorption. The treatment process is carried out by using three different types of low cost adsorbents Peanut-hull, Banana peel and Activated carbon. The effectiveness of …


Treatment Of Dye Wastewater Using Dehydrated Peanut Hull, Nikitha Shamirpet Jan 2018

Treatment Of Dye Wastewater Using Dehydrated Peanut Hull, Nikitha Shamirpet

ETD Archive

The release of dye waste water into environment causes harm to aquatic life when they reach drains or other water sources. They pollute the soil and causes change in cycles of plant and animal life through bio-accumulation and nutrient cycle. Dyes which form residue or precipitate causes mutations or changes in the DNA of living organisms in and around the area of release of the dye into atmosphere. In this thesis, several runs were attempted to treat the synthetically prepared dye waste water using dehydrated peanut hull. The initial dye waste water samples were all collected and checked for absorbance, …


A Synthesis Platform For Temperature Responsive Star Polymers, Schmitt J. Richard Jr. Jan 2018

A Synthesis Platform For Temperature Responsive Star Polymers, Schmitt J. Richard Jr.

ETD Archive

Star polymers are a class of branched polymers comprised of several polymer chains extending from a central point. Star polymers have applications in biopharmaceuticals where they have been proposed to be suitable drug delivery vehicles. Star polymers have traditionally been synthesized through chemical synthesis with added functionality provided by grafting on the arms. This complex synthesis can be simplified by using a biosynthetic approach which enables precise control of molecular weight and composition. This approach is demonstrated using star polymers with arms composed of a temperature responsive protein-based polymer termed elastin-like polypeptide (ELP). Star polymers are characterized based on the …


Predictive Simulations Of Gait And Their Application In Prosthesis Design, Anne D. Koelewijin Jan 2018

Predictive Simulations Of Gait And Their Application In Prosthesis Design, Anne D. Koelewijin

ETD Archive

Predictive simulations predict human gait by solving a trajectory optimization problem by minimizing energy expenditure. These simulations could predict the effect of a prosthesis on gait before its use. This dissertation has four aims, to show the application of predictive simulations in prosthesis design and to improve the quality of predictive simulations. Aim 1 was to explain joint moment asymmetry in the knee and hip in gait of persons with a transtibial amputation (TTA gait). Predictive simulations showed that an asymmetric gait required less effort. However, a small effort increase yielded a gait with increased joint moment symmetry and reduced …


School Logo Cleveland State University Logo Title Evolutionary Optimization For Safe Navigation Of An Autonomous Robot In Cluttered Dynamic Unknown Environments, Arash Roshanineshat Jan 2018

School Logo Cleveland State University Logo Title Evolutionary Optimization For Safe Navigation Of An Autonomous Robot In Cluttered Dynamic Unknown Environments, Arash Roshanineshat

ETD Archive

We present a path planning approach based on probabilistic methods for a robot to navigate in a cluttered, dynamic, unknown environment. There are dynamic obstacles moving around and static obstacles located in the map. The robot does not have any prior information about them but should be able to navigate through the map beginning from a known starting point and safely ending at a known target point. The only information the robot has is the location of the starting point and the target point and it uses sensory information to collect information about its surroundings. Our method is compared to …


Real-Time Assessment And Visual Feedback For Patient Rehabilitation Using Inertial Sensors, Deepa Adinarayanan Jan 2018

Real-Time Assessment And Visual Feedback For Patient Rehabilitation Using Inertial Sensors, Deepa Adinarayanan

ETD Archive

Rehabilitation exercises needs have been continuously increasing and have been projected to increase in future as well based on its demand for aging population, recovering from surgery, injury and illness and the living and working lifestyle of the people. This research aims to tackle one of the most critical issues faced by the exercise administers-Adherence or Non-Adherence to Home Exercise problems especially has been a significant issue resulting in extensive research on the psychological analysis of people involved. In this research, a solution is provided to increase the adherence of such programs through an automated real-time assessment with constant visual …


Evolutionary Optimization For Safe Navigation Of An Autonomous Robot In Cluttered Dynamic Unknown Environments, Arash Roshanineshat Jan 2018

Evolutionary Optimization For Safe Navigation Of An Autonomous Robot In Cluttered Dynamic Unknown Environments, Arash Roshanineshat

ETD Archive

We present a path planning approach based on probabilistic methods for a robot to navigate in a cluttered, dynamic, unknown environment. There are dynamic obstacles moving around and static obstacles located in the map. The robot does not have any prior information about them but should be able to navigate through the map beginning from a known starting point and safely ending at a known target point. The only information the robot has is the location of the starting point and the target point and it uses sensory information to collect information about its surroundings. Our method is compared to …


Effect Of History On The Binary Adsorption Equilibria Of Aluminium Terephthalate (Mil-53(Al)), Ufuoma Israel Kara Jan 2018

Effect Of History On The Binary Adsorption Equilibria Of Aluminium Terephthalate (Mil-53(Al)), Ufuoma Israel Kara

ETD Archive

Metal organic frameworks (MOFs) are highly porous solids with potential applications in a wide range of fields including gas separations and catalysis. Most of porous solids used in these applications such as zeolites and activated carbon usually have rigid structures. In contrast, a number of metal-organic frameworks (MOFs) exhibit structural transformation in response to external stimuli. Such materials show promise for applications such as sensors, actuators and adsorptive separations. Several thermodynamic formalisms were proposed in literature to explain this phenomenon, often known as gate-opening or “breathing” of the MOF material. In this study, the adsorptive behavior of MIL-53(Al), a MOF …


Continuous Human Activity Tracking Over A Large Area With Multiple Kinect Sensors, Akshat C. Hans Jan 2018

Continuous Human Activity Tracking Over A Large Area With Multiple Kinect Sensors, Akshat C. Hans

ETD Archive

In recent years, researchers had been inquisitive about the use of technology to enhance the healthcare and wellness of patients with dementia. Dementia symptoms are associated with the decline in thinking skills and memory severe enough to reduce a person’s ability to pay attention and perform daily activities. Progression of dementia can be assessed by monitoring the daily activities of the patients. This thesis encompasses continuous localization and behavioral analysis of patient’s motion pattern over a wide area indoor living space using multiple calibrated Kinect sensors connected over the network. The skeleton data from all the sensor is transferred to …


Stabilization Of Hypoxia Inducible Factor By Cobalt Chloride Can Alter Renal Transepithelial, Subhra Sankar Nag Jan 2018

Stabilization Of Hypoxia Inducible Factor By Cobalt Chloride Can Alter Renal Transepithelial, Subhra Sankar Nag

ETD Archive

Kidney cyst expansion, stagnant fluid accumulation, and insufficient vascular supply can result in localized chronic ischemia-hypoxia in kidney cysts, as well as in normal renal epithelia adjacent to a cyst. We hypothesize that in normal epithelia near a cyst, the stabilization of Hypoxia Inducible Factor 1a (HIF1a), a major regulator of cellular response to hypoxia, can cause altered paracellular and transcellular transport, transforming a normal absorptive phenotype to a secretory and paracellularly leaky phenotype, leading to cyst expansion. Using 100 µmol/L cobalt chloride (CoCl2), HIF1a was stabilized in cellular nucleus of a mouse cortical collecting duct cell line (mCCD 1296 …


From Blockchain To Internet-Based Voting, Elham Akbari Jan 2018

From Blockchain To Internet-Based Voting, Elham Akbari

ETD Archive

Blockchain has been one of the hottest topics among the state-of-the-art technologies. As the enabling technology for Bitcoin, the pioneering cryptocurrency, blockchain is an append-only distributed ledger that is virtually impossible to attack. Hence, blockchain holds great promises as the fundamental technology to enable Internet-based electronic voting. However, Internet-based voting has additional requirements than what monetary transactions such as Bitcoin have to offer. In this thesis, we discuss the key differences of a blockchain-based voting system with digital currencies. In this context we also highlight the requirements, review existing proposed solutions, and outline possible improvements. Specifically, we propose several schemes …


Determination Of Growth Kinetics, Yield Coefficients And Biodiesel Properties For The Green Microalgae Scenedesmus Dimorphus In Freshwater And Saline Medias, Morgan L. Cohara Jan 2018

Determination Of Growth Kinetics, Yield Coefficients And Biodiesel Properties For The Green Microalgae Scenedesmus Dimorphus In Freshwater And Saline Medias, Morgan L. Cohara

ETD Archive

Of the many alternative resources capable of generating biofuel, microalgal oil serves as a promising feedstock. Unfortunately, biodiesel production from microalgae is currently hindered by high operational costs. One primary causes for these high costs is the large quantity of freshwater required for cultivation. This experiment was designed to assess the feasibility of growing the green, freshwater microalgae Scenedesmus dimorphus in an increasingly saline environment. Both average yield coefficients and growth rates were monitored with increasing salt concentration. Determination of average yield coefficients allows for process scale-up and the optimization of production costs by minimizing raw material waste. Salinity was …


Kinetics And Ensemble Dynamics Of Colloidal Ellipsoids Near An Ac Electrode, Jiarui Yan Jan 2018

Kinetics And Ensemble Dynamics Of Colloidal Ellipsoids Near An Ac Electrode, Jiarui Yan

ETD Archive

The manipulation of colloidal particles via applying electric fields has been studied over the past 30 years due to the unique properties associated with the fabricated colloidal crystals. Most works in this field focused on utilizing an alternating current (AC) electric field with spherical particles. However, utilizing spherical colloidal particles as building blocks for complex microstructures has been challenging. Consequently, more recent work has shifted to employing complex colloids (anisotropic in nature) as building blocks for advanced materials. In our work, the phase diagram and the kinetics of assembling colloidal polystyrene ellipsoids under an AC electric field at low frequencies …


Influence Of Natural Convection During Dendritic Array Growth Of Metal Alloys (Gradient Freeze Directional Solidification), Suyog N. Mahajan Jan 2018

Influence Of Natural Convection During Dendritic Array Growth Of Metal Alloys (Gradient Freeze Directional Solidification), Suyog N. Mahajan

ETD Archive

Purpose of this study was to examine the microstructural evolution of primary dendrites during Gradient Freeze Directional Solidification process in cylindrical Pb-5.8% Sb alloy samples to generate the ground- based research data to support a future microgravity experiment on the Space Station in a convection free environment. Pb-5.8Sb was selected for this study because of its ease of processing and availability of physical property data which will be required for predicting the dendrite morphology parameters, such as, primary dendrite spacing and dendrite trunk diameter. This alloy is also susceptible to thermosolutal convection caused by density inversion of the met in …


Modeling Liver Diseases Using Hepatic Cell Microarrays, Alexander David Roth Jan 2018

Modeling Liver Diseases Using Hepatic Cell Microarrays, Alexander David Roth

ETD Archive

Hepatocellular carcinoma (HCC) is an invasive and aggressive cancer of the liver that arises due to chronic cirrhosis. Research into understanding HCC has focused on two-dimensional (2D) and three-dimensional (3D) technologies to simulate the liver microenvironment and use animal models to model how HCC affects the rest of the body. 3D hydrogel models are desired because they can mimic the transport behavior observed in vivo by structurally mimicking the extracellular matrix (ECM) without the ethical concerns of animal models. However, hydrogels can be toxic to cells and require optimal procedures for appropriate handling. In this study, we created 3D models …


Advanced Manufacturing Of Titanium Alloys For Biomedical Applications, Nicholas C. Mavros Jan 2018

Advanced Manufacturing Of Titanium Alloys For Biomedical Applications, Nicholas C. Mavros

ETD Archive

In metallurgy, Titanium has been a staple for biomedical purposes. Its low toxicity and alloying versatility make it an attractive choice for medical applications. However, studies have shown the difference in elastic modulus between Titanium alloys (116 GPa) and human bone (40-60 GPa) contribute to long term issues with loose hardware fixation. Additionally, long term studies have shown elements such as Vanadium and Aluminum, which are commonly used in Ti-6Al-4V biomedical alloys, have been linked to neurodegenerative diseases like Alzheimers and Parkinsons. Alternative metals known to be less toxic are being explored as replacements for alloying elements in Titanium alloys. …


Factors Affecting Minimum Dissolved Oxygen Concentration In Streams, Chistopher Robert Huhnke Jan 2018

Factors Affecting Minimum Dissolved Oxygen Concentration In Streams, Chistopher Robert Huhnke

ETD Archive

Modeling water quality has been shown to be a useful tool in strategizing water quality management. Dissolved oxygen (DO) has one of the largest impacts on water quality compared to other parameters. The purpose of the dissertation research is to generate a regression equation model, using the US EPA QUAL2K model as the base, to determine different factors affecting minimum dissolved oxygen concentrations in streams, to determine the critical distance for the minimum dissolved oxygen concentration, and the magnitude of impact of each parameter. Based on regression analysis, the factors affecting minimum DO in river water are effluent biochemical oxygen …


Adsorption And Microfiltration Processes To Treat Dye And Coffee Wastewater., Abhiram Siva Prasad Pamula Jan 2018

Adsorption And Microfiltration Processes To Treat Dye And Coffee Wastewater., Abhiram Siva Prasad Pamula

ETD Archive

Wastewater from coffee processing industry creates high biological and chemical oxygen demand in the surface water. In addition to coffee wastewater from coffee industry, dyes from textile industry enter surface water affecting water quality in terms of transmissivity of light. Adsorption is an economical wastewater treatment process to remove color from dye and coffee wastewater. In the current thesis, adsorption using low-cost adsorbents like peanut hull and onion peel are used to treat combined dye and coffee wastewater. Three representative dyes including acid black 48, disperse yellow 3, crystal violet certified with processed coffee is used in preparing batch adsorption …


An Anisotropic Constitutive Model For Nuclear Grade Graphite, James Christopher Jan 2018

An Anisotropic Constitutive Model For Nuclear Grade Graphite, James Christopher

ETD Archive

Graphite material is used extensively in nuclear reactors however the material has a limited strain range for elastic behavior. This provides the motivation to derive a constitutive model that captures the inelastic deformations exhibited by this material. This dissertation first presents details of an isotropic constitutive model derived using continuum principles of engineering mechanics that accounts for different inelastic behavior in tension and compression. An inelastic dissipation function was developed using an integrity basis proposed by Green and Mkrtichian (1977) for the isotropic version of the model. This isotropic model was then extended to capture anisotropic stress-strain behavior using directional …


The Role Of Synthesis Solvent In Particle Size Of Metal Organic Frameworks, Jonathan Krisak Jan 2018

The Role Of Synthesis Solvent In Particle Size Of Metal Organic Frameworks, Jonathan Krisak

Undergraduate Research Posters 2018

Metal organic frameworks are a class of nanoporous materials with pore sizes ranging from 0.5 to 3 nm and high surface areas (500-6000 m2/g). These materials have potential applications in industrial catalysis, separation and purification, bio-mimetics, drug delivery, semiconductors, sensors and other electronics. The aim of this study is to understand the role of solvent in control of the particle size of the final MOF product. CuBTC MOF has been used as a model MOF in this study to understand this effect. Altering the dielectric constant of solvents is a potential method of controlling the particle size. The data obtained …


Methodology Development For The Implementation Ofmicrofluidic Mixers, Tahir Butt, Gautam Mahajan Jan 2018

Methodology Development For The Implementation Ofmicrofluidic Mixers, Tahir Butt, Gautam Mahajan

Undergraduate Research Posters 2018

Microfluidic platforms have been widely regarded as defining technologies for the development of chemical and biological synthesis and analysis systems, due to benefits associated with reduced reactant consumption, increases by orders of magnitude of the surface-to-volume ratios, and greatly enhanced control over reactions variables such as temperature and pressure. However, one of the bottlenecks for their wide application is the difficulty in achieving mixing, given the typical laminar flows in these systems. In this work we implement experimentally, various strategies using geometrical features to control the fluid motion and induce stirring flows. The mixers are fabricated using soft-lithography in PDMS …


Implementation Of A Reverse Staggered-Herringbone Microfluidic Mixer For High-Throughput Polymeric Nanoparticles Synthesis, Alexa Roberts Jan 2018

Implementation Of A Reverse Staggered-Herringbone Microfluidic Mixer For High-Throughput Polymeric Nanoparticles Synthesis, Alexa Roberts

Undergraduate Research Posters 2018

The goal of this research is to implement and optimize the operating conditions of a microfluidic mixer to synthesize polymeric nanoparticles (NPs) in a high-throughput fashion. Using a reverse staggered-herringbone microfluidic mixer that we recently designed, the effects of experimental conditions such as flowrate and reactant composition on NP characteristics were investigated and optimized. The device design allowed for physical contact between two streams of fluids – one containing poly(lactic-co-glycolic acid; PLGA) in acetonitrile and the other deionized water, to allow for efficient mixing and NP precipitation to occur. The resulting NPs were characterized using dynamic light scattering (DLS) and …


Prediction Of Metabolism-Induced Neurotoxicity On A 384pillarplate, Rushabh Patel, Pranav Joshi, Soo-Yeon Kang, Stephen Hong, Parnian Bigdelou Jan 2018

Prediction Of Metabolism-Induced Neurotoxicity On A 384pillarplate, Rushabh Patel, Pranav Joshi, Soo-Yeon Kang, Stephen Hong, Parnian Bigdelou

Undergraduate Research Posters 2018

Metabolism of compounds including neurotoxins primarily occurs in the liver by a variety of drug-metabolizing enzymes (DMEs) followed by a series of downstream responses. Unmodified (or parent) neurotoxins are transported into human hepatocytes through several influx transporters or via passive diffusion and undergo Phase I and Phase II biotransformation by DMEs before they are cleared. Neurotoxins and their metabolites generated from human hepatocytes could potentially lead to the toxic effects on neural stem cells (NSCs) as the reactive metabolites have potential for producing reactive oxygen species (ROS), which can lead to irreversible oxidative damage to NSCs via lipid peroxidation, DNA, …