Engineering Commons^™

State Estimation Of Glucose And Insulin Dynamics, Morgan Nicholas Miller

ETD Archive

Process simulation and state estimation have very important applications in chemical engineering as well as the biomedical field. Diabetes is a rapidly growing disease in the United States with 29 million people already diagnosed. The estimation of glucose and insulin concentration in patients is necessary in order to effectively treat diabetes. The Bergman Minimal Model is a popular process model that is used to simulate glucose and insulin dynamics. A simulation of this model was created based on estimated parameters for the model from historical data. This thesis investigated the estimation of glucose concentration, insulin concentration, and effect of active …

Field Observation Of Installation And Performance Of Repair Materials, Larisa Diana Susinskas

ETD Archive

The state of Ohio is in a region that commonly experiences drastic changes in weather. States with similar climates are susceptible to pavement cracking and failures due to the frequent or extreme freeze-thaw cycles. Freeze-thaw cycles, paired with de-icing chemicals that are frequently placed on roadways during the winter months will most likely lead to pavement cracks and failure. Ohio Department of Transportation (ODOT) routinely repairs and replaces sections of concrete roadways and bridge decks. Therefore, ODOT is seeking durable, cost-effective materials to repair smaller pavement failures.

The purpose of this study is to determine which high performance repair materials …

Specification Recommendation For Use Of High Performance Repair Material, Jennifer Woods

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The State of Ohio and the Ohio Department of Transportation (ODOT) have sought out ways to extend the life of the repair materials used by their construction crews, specifically, using high performance repair materials for the purposes of patching worn down or cracked sections of highways and bridge decks. Ohio is known for its frequent changes in weather, with freeze-thaw cycles occurring multiple times throughout the year. These cycles affect the lifespan of the repair material and create more maintenance for the DOT. Products that combat this problem were chosen, installed and examined over a year period to determine which …

Effects Of Digestate, Magnesium Sulfate, And Dipotassium Hydrogen Phosphate/Potassium Dihydrogen Phosphate On Microalga, Scenedesmus Dimorphus, Zhuohui Joe He

ETD Archive

Digestate (D), the remaining substance after anaerobic digestion of a biodegradable feedstock, is rich in inorganic contents, which makes it a good candidate for growing algae for biofuel production. Previous studies showed digestate at around 1.25% to 1.75% (v/v) dilution is suitable for algae growth. In this study, magnesium sulfate (MgSO4) and dipotassium hydrogen phosphate/potassium dihydrogen phosphate (K-P) were added to diluted digestate growth media. Two sets of experiments were conducted in batch reactor mode to identify the digestate (D), magnesium sulfate (MgSO4) and dipotassium hydrogen phosphate/potassium dihydrogen phosphate (K-P) concentrations that would optimize the algae growth. Algae growth parameters, …

The Response Of An Ellipsoidal Colloid Particle In An Ac Field, Cornelius Adebowale Obasanjo

ETD Archive

The quest for new smart materials with engineered properties and desired functionalities has driven scientists into the domain of nanotechnology over the past 30 years. Particles with anisotropic properties as a result of their geometry, chemical patterning or surface functionality have been envisioned as building blocks for advanced materials. By tuning the anisotropic interactions engendered by anisotropic particles, one potentially could manipulate the dynamic pathways for assembly.

The work described in this thesis considers the response of an ellipsoidal colloid particle to a nearby AC electrode polarized at ~0.1 – 4 kV/m and ~0.1 – 3 kHz. The ellipsoidal particle, …

The Behavior Of Simply Supported Plates Under Extreme Shear Loading, Mhd Ammar Hafez

ETD Archive

Steel plates are planar structural elements with one dimension significantly smaller than the others. These elements may fail due to either material yielding or buckling. Buckling is a sudden failure mode, which is not desirable in structural engineering applications. Buckling is called an “elastic buckling” when it happens before material yielding, and is termed as “plastic buckling” if it happens after material yielding. The focus of this thesis is on shear plates, which are plates that are primarily subjected to shear loads. Several studies were conducted to increase the elastic buckling capacity of plates by adding stiffeners to plates. However, …

A Simulation And Experimental Study Of Active Disturbance Rejection For Industrial Pressure Control, Xiaoxu Li

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The quality of control loop is very important in hydraulic machineries, where pressure must be accurately regulated in the presence of various disturbances. Proportional-Integral-Derivative (PID) control has dominated the industry for a long time and it is by far the most popular general purpose controller for pressure control. The purpose of this study is to conduct a simulation and experimental study comparing PID with an emerging new technology, namely active disturbance rejection control (ADRC). For the purpose of this study, an experimental testbed similar to those used in industry settings is used; its mathematic model is derived and used in …

Characterization Of Performance Of A 3d Printed Stirling Engine Through Analysis And Test, Julie Vodhanel

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This thesis involves the fusion of two technologies, Stirling engines and additive
manufacturing. The project began by building a Stirling engine primarily out of 3D printed parts. Methods to measure the power output were designed and built with a combination of 3D printed and off the shelf parts. The Stirling engine was tested to see if there was a correlation to analysis results, and a regenerator was installed to determine the effect on performance for this relatively low temperature engine. Finally, variations in test operation and the use of heat sinks were used to find a combination that will allow …

Design And Production Of A Hydrogel Forming Polypeptide: Engaging High School Students In Protein Design, James K. Deyling

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Bioinks are a class of hydrogel that have the potential to be the ink used in the creation of printed organs, connective tissue, and other important structures within the body. One class of material that may be a suitable bioink hydrogel is elastin-like polypeptides (ELPs), which are synthetic biopolymers inspired by the naturally existing connective tissue elastin. ELPs consist of a repeat pentapeptide sequence (GXGVP)n, where X is any of the 20 naturally existing amino acids other than proline. These biomolecules are capable of exhibiting environmental responsiveness when exposed to certain stimulus such as salt concentration, temperature, and pH, depending …

Evaluation Of The Performance Of A Downward Flow Inclined Gravity Settler For Algae Dewatering, Dustin D. Bowden

ETD Archive

With recent concerns over the environmental implications of burning fossil fuels coupled with the depletion of fossil fuel reserves an alternative source of energy isneeded. Algae derived biofuels may be an effective replacement for transportation fuels as they are carbon neutral and have a high area productivity. Algae is superior to terrestrial plants as a biofuel source due to its high oil productivity and efficiency along with the fact that it will not displace food production. Currently the largest obstacle to the implementation of commercial algae to biofuel processes is algae dewatering. The separation of algae from water is difficult …

Determining The Transport Enhancement Of Sodium Fluorescein In Mechanically-Loaded Canine Tibia, Andrew Joseph Zak

ETD Archive

Quantitative research concerning the impact of mechanical loading on the transport properties of bone has several critical applications. One such application is the effect of a microgravity environment, where the lack of mechanical forces on bone has been shown to negatively impact both growth and repair. A method has been developed in our lab that can potentially allow for the measurement of the effective permeability of large molecules (i.e., 300-15,000 Da in size) in bone tissue under both unloaded and mechanically loaded conditions. In proof-of-concept experiments, previous students have measured the effective diffusivity of the model solute, sodium fluorescein (376 …

Laboratory Testing Of High Performance Repair Materials For Pavements And Bridge Decks, Kamran Amini

ETD Archive

Because of numerous freezing and thawing cycles happening during the year in the state of Ohio, pavement partial-depth patching has become a common maintenance activity in this state. The Ohio Department of Transportation (ODOT) has a need for durable, more permanent high performing pavement and bridge deck materials that allow for a faster repair and for user safety. However, new or proprietary products are difficult to specify unless incorporated into a construction project for research purposes or procurement of the product complies with the ODOT's direct purchasing requirements.This research project was conducted in three main phases, literature review and selecting …

Time And Temperature Dependent Surface Tension Measurements Of Responsive Protein-Based Polymer Surfactant Solutions, Hakan Celik

ETD Archive

A three-armed star elastin-like polypeptide (ELP-foldon) has thermoreversible character which exhibits phase separation above a transition temperature (Tt) in physiologic salt concentrations. At lower salt concentration, the ELP-foldon behaves like a thermoresponsive surfactant, exhibiting micelle formation above its Tt. The purpose of this study is characterize the surfactant behavior of the ELP-foldon at air-liquid interface by measuring the surface tension. The surface tension is measured as a function of time for different ELP concentrations from 10 nM to 50 ℗æM and over range of temperatures from 25 to 35 ℗¿ using the axisymmetric drop shape analysis (ADSA). The ADSA is …

Solute Partitioning In Elastin-Like Polypeptides: A Foundation For Drug Delivery Applications, Eric Helm

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No abstract provided.

Characterization Of Highly Concentrated Elastin-Like Polypeptide Solutions: Rheometric Properties And Phase Separation Analysis, Kevin Michael Otto

ETD Archive

Elastin-like polypeptides (ELPs) are environmentally responsive biopolymers. These protein based polymers are specific in that they exhibit phase separation in response to a number of stimuli. Some of these stimuli include temperature, light, and pH. There are a large number of factors to consider when designing ELP constructs that allow for control of the transitioning behavior, some of which include amino acid sequences, protein concentration, salt concentration, and the polymer chain length. Elastin-like polypeptides are soluble in water at low temperatures, however, upon an increase in temperature, the proteins become insoluble in water and phase separate. This point of temperature …

Analytical And Numerical Validation Of Nozzle Spray Measurement Data Obtained From A Newly Developed Production System, Iddrisu Seidu

ETD Archive

A newly developed production test stand for measuring the spray angle of a pressure swirl atomizer was constructed and used to measure a product line of these pressure swirl atomizers -- the macrospray atomizer. This new test stand, utilizing constant temperature hot wire anemometers, captures the spray angle data based on the voltage drop the hot wire probes see as they traverse the spray cone of the atomizer and as fluid droplets impinge upon the wire. Datasets acquired from the experiments are compared and correlated with computational fluid dynamics (CFD) simulation data. In addition, angles obtained from another type of …

Comparison Of Criteria Used By State Transportation Agencies To Evaluate Proposed Lane Closures In Planned Work Zones, Sudheer Penimicha

ETD Archive

The purpose of this thesis was to compare the specific performance measures used by various state transportation agencies across the United States to evaluate the impact of proposed lane closures on the interstate system and decide whether the impact is acceptable or not, and thus whether or not to approve the proposed lane closure. Information about the policies, processes, and procedures for approving lane closures was obtained through a combination of searching the webpages of individual state departments of transportation, downloading pertinent materials, emailing requests for information, and contacting agency personnel by telephone. The collected documents and notes taken during …

Skill Retention For Driving Simulation Experiments, Nikhil Ravindra Sarwate

ETD Archive

Whether driving a car in the real world or a simulator vehicle in a computer generated world, the procedural aspects of driving are very similar. The steering wheel is used to control the direction of the vehicle while the accelerator and brake pedals are used to control the speed. This similarity means that people who already possess the skill of driving in the real world are expected to transfer those existing skills to drive a simulator vehicle. Recognizing the need for skill transference, the typical protocol for conducting driving simulation experiments includes a practice drive, which affords participants the opportunity …

Dynamic Model Of A Non-Linear Pneumatic Pressure Modulating Valve Using Bond Graphs, Christopher L. Brubaker

ETD Archive

This research develops a mathematical model of the dynamic pressure response to a variable travel input of a pneumatic pressure modulating valve intended for use in a vehicle air brake system. Generically, the valve is a multi-domain system consisting of a mechanical portion and a pneumatic portion. Included in the mechanical portion of the model are compliance of the springs, inertia of the components, and resistance of the sliding components. The pneumatic portion of the model includes capacitance due to the compressibility of the gas, flow resistance through connected plumbing, and flow resistance through the valve control orifices. The development …

Optimal Design And Control Of A Lower-Limb Prosthesis With Energy Regeneration, Holly E. Warner

ETD Archive

The majority of amputations are of the lower limbs. This correlates to a particular need for lower-limb prostheses. Many common prosthesis designs are passive in nature, making them inefficient compared to the natural body. Recently as technology has progressed, interest in powered prostheses has expanded, seeking improved kinematics and kinetics for amputees. The current state of this art is described in this thesis, noting that most powered prosthesis designs do not consider integrating the knee and the ankle or energy exchange between these two joints. An energy regenerative, motorized prosthesis is proposed here to address this gap. After preliminary data …

A Generalized Control Method For Constant Switching Frequency Three Phase Pwm Boost Rectifier Under Extreme Unbalanced Operation Condition, Abhishek Kumar Upadhyay

ETD Archive

This thesis presents a generalized control method for constant switching frequency PWM Boost Type Rectifier under extremely unbalanced operating conditions in the power system. The proposed analytical method is verified by using MATLAB/ Simulink model developed under severe unbalanced conditions of input source voltages and input impedances. The closed loop control method for controlling the output DC voltage is also presented and verified by using MATLAB/Simulink model. An experimental model is built to prove the feasibility of the proposed constant switching frequency operation of the PWM Boost Type Rectifier under extreme unbalanced operation conditions by using DSPACE RT1104 digital control …

High Speed Clock Glitching, Santosh Desiraju

ETD Archive

In recent times, hardware security has drawn a lot of interest in the research community. With physical proximity to the target devices, various fault injection hardware attack methods have been proposed and tested to alter their functionality and trigger behavior not intended by the design. There are various types of faults that can be injected depending on the parameters being used and the level at which the device is tampered with. The literature describes various fault models to inject faults in clock of the target but there are no publications on overclocking circuits for fault injection. The proposed method bridges …

The Design And Implementation Of A Kinect-Based Rehabilitation Exercise Monitoring And Guidance System, Hai Feng

ETD Archive

In preventive and rehabilitative healthcare, physical exercise is a powerful intervention. However, a program may require in the range of thousands of practice repetitions, and many people do not adhere to the program or perform their home exercises incorrectly, making the exercise ineffective, or even dangerous. This thesis research aims to develop a Kinect-based system for rehabilitation exercises monitoring and guidance. In the first step, a feasibility study was carried out on using Kinect for realtime monitoring of rehabilitation exercises while a multi-camera motion tracking system was used to establish the ground truth. In the second step, a Unity-based system …

Analysis Of Smartphone Traffic, Nicholas Luke Ruffing

ETD Archive

Smartphone reconnaissance, the first step to launch security attacks on a target smartphone, enables an adversary to tailor attacks by exploiting the known vulnerabilities of the target system. We investigate smartphone OS identification with encrypted traffic in this paper. Four identification algorithms based on the spectralanalysis of the encrypted traffic are proposed. The identification algorithms are designed for high identification accuracy by removing noise frequency components and for high efficiency in terms of computation complexity. We evaluate the identification algorithms with smartphone traffic collected over three months. The experimental results show that the algorithms can identify the smartphone OS accurately. …

Application Aware For Byzantine Fault Tolerance, Hua Chai

ETD Archive

Driven by the need for higher reliability of many distributed systems, various replication-based fault tolerance technologies have been widely studied. A prominent technology is Byzantine fault tolerance (BFT). BFT can help achieve high availability and trustworthiness by ensuring replica consistency despite the presence of hardware failures and malicious faults on a small portion of the replicas. However, most state-of-the-art BFT algorithms are designed for generic stateful applications that require the total ordering of all incoming requests and the sequential execution of such requests. In this dissertation research, we recognize that a straightforward application of existing BFT algorithms is often inappropriate …

Potential Optimal Gait Performance Of Mauch S-N-S Prosthetic Knee Configurations As Predicted By Dynamic Modeling, Chih-Hao Chien

ETD Archive

Patients with prosthetic legs routinely suffer from abnormal gait patterns which can cause health issues and eventually lower the quality of their lives. Despite the half-century advance in the technology of prosthetic knees, from the purely mechanical to microprocessor controlled systems, patient testing suggests that very little progress has been made in the quality of the kinetics and kinematics of amputee gait. Moreover, the cost of microprocessor controlled prosthetic knees may be 10 times more than the purely mechanical knees. While prosthetic knees have become more complex and expensive, it is not proven that the prosthetic knee is a central …

Biogeography-Based Optimization For Combinatorial Problems And Complex Systems, Dawei Du

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Biogeography-based optimization (BBO) is a heuristic evolutionary algorithm that has shown good performance on many problems. In this dissertation, three problem1s 1 are researched for BBO: convergence speed and optimal solution convergence of BBO,1 1BBO application to combinatorial problems, and BBO application to complex systems. The first problem is to analyze BBO from two perspectives: how the components of BBO affect its convergence speed and the reason that BBO converges to the optimal solution. For the first perspective, which is convergence speed, we analyze the two essential components of BBO -- population construction and information sharing. For the second perspective, …

Oppositional Biogeography-Based Optimization, Mehmet Ergezer

ETD Archive

This dissertation outlines a novel variation of biogeography-based optimization (BBO), which is an evolutionary algorithm (EA) developed for global optimization. The new algorithm employs opposition-based learning (OBL) alongside BBO migration to create oppositional BBO (OB BO). Additionally, a new opposition method named quasi-reflection is introduced. Quasireflection is based on opposite numbers theory and we mathematically prove that it has the highest expected probability of being closer to the problem solution among all OBL methods that we explore. Performance of quasi-opposition is validated by mathematical analysis for a single-dimensional problem and by simulations for higher dimensions. Experiments are performed on benchmark …

Development Of Chatter Attenuation Robust Control For An Amb Machine Spindle, Alexander Hans Pesch

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No abstract provided.

A Probabilistic Based Failure Model For Components Fabricated From Anisotropic Graphite, Chengfeng Xiao

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The nuclear moderator for high temperature nuclear reactors are fabricated from graphite. During reactor operations graphite components are subjected to complex stress states arising from structural loads, thermal gradients, neutron irradiation damage, and seismic events. Graphite is a quasi-brittle material. Two aspects of nuclear gradegraphite, i.e., material anisotropy and different behavior in tension and compression, are explicitly accounted for in this effort. Fracture mechanic methods are useful for metal alloys, but they are problematic for anisotropic materials with a microstructure that makes it difficult to identify a "critical" flaw. In fact cracking in a graphite core component does not necessarily …