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Design And Synthesis Of Polymer - Magnetic Nanoparticle Composites For Use In Biomedical Applications, Roland Stone
Design And Synthesis Of Polymer - Magnetic Nanoparticle Composites For Use In Biomedical Applications, Roland Stone
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The future of diagnostics and therapeutic drugs in biomedicine is nanoparticles. These nanoparticles come in many different shapes, sizes, and combination of materials. Magnetic nanoparticles have been studied for many years for use in biomedicine, not only for their high surface area, but also because of its unique magnetic properties. They can magnetically interact with their environment, be guided to a specific location, and manipulated to release energy in the form of heat. To ensure that these magnetic nanoparticles survive in the circulatory system, they must be modified with materials to make them colloidally stable in water and shield them …
Aqueous Suspensions Of Polymer Coated Magnetite Nanoparticles: Colloidal Stability, Specific Absorption Rate, And Transverse Relaxivity, Steven Saville
Aqueous Suspensions Of Polymer Coated Magnetite Nanoparticles: Colloidal Stability, Specific Absorption Rate, And Transverse Relaxivity, Steven Saville
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The design, functionalization, characterization, and applications of magnetic nanoparticles have garnered significant interest over the past several decades. While this area has garnered increasing attention, several questions remain unanswered about the stability of these systems and it's influence on their biomedical applications. To help answer these questions about the stability of these, a novel tri(nitroDOPA) terminated polymer based ligand has been developed for the stabilization of magnetite nanoparticles. The synthesis involves a process in which ethylene oxide is polymerized using a trivinyl initiator, modified with carboxylic acid using a free radical addition of mercaptoundecanoic acid, and then functionalized with nitroDOPA …