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ENGS 88 Honors Thesis (AB Students)

2019

Biosensors

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Shape Effects Of Gold Coated Silica Nanoparticles For Localized Plasmonic Resonance Based Biosensing, Russell Beckerman Jun 2019

Shape Effects Of Gold Coated Silica Nanoparticles For Localized Plasmonic Resonance Based Biosensing, Russell Beckerman

ENGS 88 Honors Thesis (AB Students)

Gold coated silica (Au@SiO2) nanoparticles are promising optical transducers for biosensors due to localized surface plasmonic resonance (LSPR) sensitivity to changes in refractive index. This study investigates the effects of shape, size, and structure on LSPR sensitivity of Au@SiO2 nanoparticles of spherical, rod, and ellipsoid geometries. Finite-difference time domain simulations in CST were used to examine these key parameters of interest and guided particle synthesis. Simulation and experiments show rod-shaped Au@SiO2 nanoparticles had maximum sensitivity of 969nm/RIU, an improvement over most particles in current literature. This study examines a method for enhanced LSPR-biosensors that leverages advances …