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Fabricating Electrodes For Amperometric Detection In Hybrid Paper/Polymer Lab-On-A-Chip Devices, Neus Godino, Robert Gorkin Iii, Ken Bourke, Jens Ducree
Fabricating Electrodes For Amperometric Detection In Hybrid Paper/Polymer Lab-On-A-Chip Devices, Neus Godino, Robert Gorkin Iii, Ken Bourke, Jens Ducree
Robert Gorkin III
We present a novel, low-resource fabrication and assembly method for creating disposable amperometric detectors in hybrid paper-polymer devices. Currently, mere paper-based microfluidics is far from being able to achieve the same level of process control and integration as state-of-the-art microfluidic devices made of polymers. To overcome this limitation, in this work both substrate types are synergistically combined through a hybrid, multi-component/multi-material system assembly. Using established inkjet wax printing, we transform the paper into a profoundly hydrophobic substrate in order to create carbon electrodes which are simply patterned from carbon inks via custom made adhesive stencils. By virtue of the compressibility …
Centrifugal Automation Of A Triglyceride Bioassay On A Low-Cost Hybrid Paper-Polymer Device, Neus Godino, Elizaveta Vereshchagina, Robert Gorkin Iii, Jens Ducree
Centrifugal Automation Of A Triglyceride Bioassay On A Low-Cost Hybrid Paper-Polymer Device, Neus Godino, Elizaveta Vereshchagina, Robert Gorkin Iii, Jens Ducree
Robert Gorkin III
We present a novel paper-polymer hybrid construct for the simple automation of fundamental microfluidic operations in a lab-on-a-disc platform. The novel design, we term a paper siphon, consists of chromatographic paper strips embedded along a siphon microchannel. The paper siphon relies on two main interplaying forces to create unique valving and liquid-sampling methods in centrifugal microfluidics. At sufficiently low speeds, the inherent wicking of the paper overcomes the rotationally induced centrifugal force to drive liquids towards inwards positions of the disc. At elevated speeds, the dominant centrifugal force will extract liquid from the siphon paper strip towards the edge of …