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Experiment, Thermal Simulation, And Characterizations On Transmission Laser Coating Of Hydroxyapatite On Metal Implant, Gary Cheng, Chang Ye
Experiment, Thermal Simulation, And Characterizations On Transmission Laser Coating Of Hydroxyapatite On Metal Implant, Gary Cheng, Chang Ye
Dr. Chang Ye
Coating of bioceramic material, Hydroxyapatite (HAp), on metal implant has attracted many attentions in biomedical industry recently because its combination of good mechanical property and biocompatibility. However, most of current HAp coatings lack coating/substrate interfacial strength, and/or biocompatibility. The cell-tissue attachment is affected by the degraded biocompatibility due to decomposition of HAp during high temperature processing. In this article, an innovative method, transmission laser coating (TLC), is investigated to coat HAp on Ti substrate with low temperature processing. This process enhances the HAp/Metal interfacial property of current coatings, while maintaining good biocompatibility. Experiments are conducted using a continuous neodymium-doped yttrium …
Effect Of Osteonectin-Derived Peptide On The Viscoelasticity Of Hydrogel/Apatite Nanocomposite Scaffolds, Alireza Sarvestani, Xuezhong He, Esmaiel Jabbari
Effect Of Osteonectin-Derived Peptide On The Viscoelasticity Of Hydrogel/Apatite Nanocomposite Scaffolds, Alireza Sarvestani, Xuezhong He, Esmaiel Jabbari
Esmaiel Jabbari
No abstract provided.
Quantification Of The Binding Affinity Of A Specific Hydroxyapatite Binding Peptide, Michael Weiger, Jung Park, Marc Roy, Christopher Stafford, Alamgir Karim, Matthew Becker
Quantification Of The Binding Affinity Of A Specific Hydroxyapatite Binding Peptide, Michael Weiger, Jung Park, Marc Roy, Christopher Stafford, Alamgir Karim, Matthew Becker
Alamgir Karim
The genesis of bone and teeth involves highly coordinated processes, which involve multiple cell types and proteins that direct the nucleation and crystallization of inorganic hydroxyapatite (HA). Recent studies have shown that peptides mediate the nucleation process, control HA microstructure or even inhibit HA mineralization. Using phage display technology, a short peptide was identified that binds to crystalline HA and to HA-containing domains of human teeth with chemical and morphological specificity. However, the binding affinity and specific amino acids that significantly contribute to this interaction require further investigation. In this study, we employ a microfluidic chip based surface plasmon resonance …