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Full-Text Articles in Engineering

The Evaluation Of A 2d Diode Array In "Magic Phantom" For Use In High Dose Rate Brachytherapy Pretreatment Quality Assurance, Anthony A. Espinoza, Marco Petasecca, Iolanda Fuduli, Andrew Howie, Joseph A. Bucci, Stephanie Corde, Michael Jackson, Michael L. F Lerch, Anatoly B. Rosenfeld Aug 2015

The Evaluation Of A 2d Diode Array In "Magic Phantom" For Use In High Dose Rate Brachytherapy Pretreatment Quality Assurance, Anthony A. Espinoza, Marco Petasecca, Iolanda Fuduli, Andrew Howie, Joseph A. Bucci, Stephanie Corde, Michael Jackson, Michael L. F Lerch, Anatoly B. Rosenfeld

Stéphanie Corde

Purpose: High dose rate (HDR) brachytherapy is a treatment method that is used increasingly worldwide. The development of a sound quality assurance program for the verification of treatment deliveries can be challenging due to the high source activity utilized and the need for precise measurements of dwell positions and times. This paper describes the application of a novel phantom, based on a 2D 11 x 11 diode array detection system, named "magic phantom" (MPh), to accurately measure plan dwell positions and times, compare them directly to the treatment plan, determine errors in treatment delivery, and calculate absorbed dose. Methods: The …


Optimal Energy For Cell Radiosensitivity Enhancement By Gold Nanoparticles Using Synchrotron-Based Monoenergetic Photon Beams, Wan Nordiana Rahman, Stephanie Corde, Naoto Yagi, Siti Aishah Abdul Aziz, Nathan Annabell, Moshi Geso Jan 2015

Optimal Energy For Cell Radiosensitivity Enhancement By Gold Nanoparticles Using Synchrotron-Based Monoenergetic Photon Beams, Wan Nordiana Rahman, Stephanie Corde, Naoto Yagi, Siti Aishah Abdul Aziz, Nathan Annabell, Moshi Geso

Stéphanie Corde

Gold nanoparticles have been shown to enhance radiation doses delivered to biological targets due to the high absorption coefficient of gold atoms, stemming from their high atomic number (Z) and physical density. These properties significantly increase the likelihood of photoelectric effects and Compton scattering interactions. Gold nanoparticles are a novel radiosensitizing agent that can potentially be used to increase the effectiveness of current radiation therapy techniques and improve the diagnosis and treatment of cancer. However, the optimum radiosensitization effect of gold nanoparticles is strongly dependent on photon energy, which theoretically is predicted to occur in the kilovoltage range of energy. …