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Full-Text Articles in Engineering
The Study Of Photo-Reduction Of Cerium Oxide Nanoparticles In Presence Of Dextran: An Attempt In Understanding The Functionality Of The System, Swetha Barkam
Electronic Theses and Dissertations
Malignant melanoma cancer is the sixth common cancer diagnosed in the United States. Surgery, chemotherapy and radiation are some of the successful techniques in killing tumor cells. However, in these techniques, it is not easy to distinguish tumor cells from the healthy once which inadvertently get exposed to chemical agent/radiation. Therefore it is required to develop an anticancer agent which selectively kills the cancer cells, while still protecting the normal tissues. In our preliminary work, we have shown that Dextran (1000Da) coated Cerium oxide nanoparticles (Dex-CNPs) selectively kills the cancer cells (50% killing at a concentration of 150μM) without inducing …
Tailoring The Properties Of Polyelectrolyte Coated Cerium Oxide Nanoparticles As A Function Of Molecular Weight, Shashank Saraf
Tailoring The Properties Of Polyelectrolyte Coated Cerium Oxide Nanoparticles As A Function Of Molecular Weight, Shashank Saraf
Electronic Theses and Dissertations
The application of Cerium oxide nanoparticles (CNPs) for therapeutic purposes requires a stable dispersion of nanoparticles in biological environment. The objective of this study is to tailor the properties of polyelectrolyte coated CNPs as a function of molecular weight to achieve a stable and catalytic active dispersion. This was achieved by coating CNPs with polyacrylic acid (PAA) which increased the dispersion stability of CNPs and enhanced the catalytic ability. The stability of PAA coating was analysed using the change in the Gibbs free energy computed by Langmuir adsorption model. The adsorption isotherms were determined using soft particle electrokinetics which overcomes …