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Chemical Engineering

University of Massachusetts Amherst

2017

Chitosan

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Synthesis Of Biopolymer Materials Tailored For Biological Applications, Nathan P. Birch Mar 2017

Synthesis Of Biopolymer Materials Tailored For Biological Applications, Nathan P. Birch

Doctoral Dissertations

Biopolymers are able to address a wide variety of medical concerns from chronic wounds to stem cell cultivation to antibacterial and antifouling applications. They are non-toxic, biodegradable, and biocompatible, making them ideal candidates for creating green materials for biological applications. In this thesis, we cover the synthesis of two novel materials from the biopolymers, chitosan and pectin. Chitosan is a biocompatible antibacterial polycation and pectin is an anti-inflammatory polyanion with a strong propensity for hydrogen-bonding. The two chitosan:pectin materials, particles and hydrogels, explore some of the structures that can be created by tuning the electrostatic interactions between chitosan and pectin. …